4-NITRO-ISATOIC ANHYDRIDE

Product Name: 4-NITRO-ISATOIC ANHYDRIDE
CAS No.: 63480-10-4
Chemical Name: 4-NITRO-ISATOIC ANHYDRIDE
Synonyms: NSC 135175;4-NITRO-ISATOIC ANHYDRIDE;4-Nitroisatoicanhydride97%;4-Nitroisatoic anhydride 97%;7-nitro-1H-3,1-benzoxazine-2,4-dion;7-nitro-1H-3,1-benzoxazine-2,4-dione;7-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione;7-NITRO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE;2H-3,1-Benzoxazine-2,4(1H)-dione, 7-nitro-;7-nitro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione
CBNumber: CB2744890
Molecular Formula: C8H4N2O5
Formula Weight: 208.13
MOL File: 63480-10-4.mol

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4-NITRO-ISATOIC ANHYDRIDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: wooly crystalline powder
color: Lemon
CAS DataBase Reference: 63480-10-4(CAS DataBase Reference)

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N515280
Product name: 4-NitroisatoicAnhydride
Packaging: 1g
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: OR400019
Product name: 4-Nitroisatoicanhydride
Purity: 95%
Packaging: 1g
Price: $19
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-1-59
Product name: 4-Nitroisatoic anhydride
Packaging: 1g
Price: $32
Updated: 2021/12/16

AK Scientific

Product number: W7542
Product name: 4-Nitroisatoicanhydride
Packaging: 1g
Price: $34
Updated: 2021/12/16

Apolloscientific

Product number: OR400019
Product name: 4-Nitroisatoicanhydride
Purity: 95%
Packaging: 5g
Price: $58
Updated: 2021/12/16

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4-NITRO-ISATOIC ANHYDRIDE Chemical Properties,Usage,Production

Synthesis

32315-10-9

619-17-0

63480-10-4

The general procedure for the synthesis of 7-nitro-1H-benzo[d][1,3]oxazine-2,4-dione from tritiated gas and 2-amino-4-nitrobenzoic acid was as follows: to a 500 mL single-necked round-bottomed flask equipped with a soccer ball shaped PTFE stirring bar (16 mm × 37 mm) was added 2-amino-4-nitrobenzoic acid (10.0 g, 46.3 mmol, 1.0 eq. ), followed by tetrahydrofuran (230 mL, 0.2 M) and solid triphosgene (13.7 g, 46.3 mmol, 1.0 eq.) to form a suspension. The reaction flask was placed in a device equipped with a metal heating jacket with a 24/40 Liebig condenser attached to the neck of the flask. The suspension was stirred at 500 rpm and the temperature of the heating jacket was set to 70°C. After about 30 minutes, the suspension became homogeneous and subsequently precipitated a white solid. The non-homogeneous reaction mixture was allowed to stand for 12 hours and then cooled to room temperature (25°C). The reaction slurry was poured into a 600 mL beaker equipped with an overhead mechanical stirrer (PTFE 75 mm paddle) and 250 mL of deionized water was added. Under vigorous stirring, the mixture first became homogeneous and then precipitated as a pale white solid. The solids were collected by vacuum filtration through a Brinell funnel (7.6 cm diameter, lined with Whatman 1 filter paper, 70 mm) and purged with air for 5 min. The resulting solids were transferred to a 250 mL conical flask, 50 mL of methanol was added, and the slurry was stirred using a cylindrical rod for 10 min, after which the solids were again collected by vacuum filtration. The filter cake was dried under vacuum (0.1 mmHg, 25 °C) for 12 h. The final product was 7-nitro-1H-benzo[d][1,3]oxazine-2,4-dione as a white powder in 90% yield.

References

[1] Beilstein Journal of Organic Chemistry, 2018, vol. 14, p. 2529 - 2536
[2] European Journal of Medicinal Chemistry, 1994, vol. 29, # 12, p. 925 - 940
[3] Patent: EP1719771, 2006, A1. Location in patent: Page/Page column 51
[4] Journal of Agricultural and Food Chemistry, 2015, vol. 63, # 31, p. 6883 - 6889

4-NITRO-ISATOIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-NITRO-ISATOIC ANHYDRIDE Suppliers

China 73 Europe 2 France 1 Germany 2 India 2 Switzerland 1 United Kingdom 6 United States 17 Global 104

Alchem Pharmtech,Inc.

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View Lastest Price from 4-NITRO-ISATOIC ANHYDRIDE manufacturers

Career Henan Chemical Co

Product: 4-NITRO-ISATOIC ANHYDRIDE 63480-10-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-07

63480-10-4, 4-NITRO-ISATOIC ANHYDRIDERelated Search:

Trimellitic Anhydride 2-Amino-4-nitrobenzoic acid 4-NITRO-ISATOIC ANHYDRIDE 1,4-dihydro-2H-3,1-benzoxazin-2-one 2-AMINO-4-NITROBENZENEMETHANOL Isatoic Anhydride 2,4-Diaminobenzoic acid 4-AMINOISATOIC ANHYDRIDE

7-NITRO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE

4-NITRO-ISATOIC ANHYDRIDE

4-Nitroisatoic anhydride 97%

7-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione, 7-Nitro-1H-benzo[d][1,3]oxazine-2,4-dione

NSC 135175

7-nitro-1H-3,1-benzoxazine-2,4-dion

4-Nitroisatoicanhydride97%

2H-3,1-Benzoxazine-2,4(1H)-dione, 7-nitro-

7-nitro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione

7-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione

7-nitro-1H-3,1-benzoxazine-2,4-dione

63480-10-4

63480-10-1

C8H4N2O5