ChemicalBook > CAS DataBase List > 5-CHLORO-2-METHYLINDOLE

5-CHLORO-2-METHYLINDOLE

Product Name: 5-CHLORO-2-METHYLINDOLE
CAS No.: 1075-35-0
Chemical Name: 5-CHLORO-2-METHYLINDOLE
Synonyms: RARECHEM AH BS 0087;TIMTEC-BB SBB003903;2-METHYL-5-CHLOROINDOLE;5-CHLORO-2-METHYLINDOLE;5-Chloro-2-methylindole >5-Chloro-2-methyl-1H-indole;5-Chloro-2-methylindole,95%;2-Methyl-5-chloro-1H-indole;5-CHLORO-2-METHYLINDOLE 97%;1H-Indole, 5-chloro-2-methyl-
CBNumber: CB2755678
Molecular Formula: C9H8ClN
Formula Weight: 165.62
MOL File: 1075-35-0.mol

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5-CHLORO-2-METHYLINDOLE Property

Melting point:: 112-118 °C
Boiling point:: 140 °C / 0.1mmHg
Density: 1.1705 (rough estimate)
refractive index: 1.5390 (estimate)
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 16.66±0.30(Predicted)
color: White to Gray to Brown
InChIKey: WUVWAXJXPRYUME-UHFFFAOYSA-N
CAS DataBase Reference: 1075-35-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 24/25-36-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C52802
Product name: 5-Chloro-2-methylindole
Purity: 97%
Packaging: 1g
Price: $124
Updated: 2022/05/15

Sigma-Aldrich

Product number: C52802
Product name: 5-Chloro-2-methylindole
Purity: 97%
Packaging: 10g
Price: $744
Updated: 2022/05/15

TCI Chemical

Product number: C1761
Product name: 5-Chloro-2-methylindole
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $67
Updated: 2025/07/31

TCI Chemical

Product number: C1761
Product name: 5-Chloro-2-methylindole
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $197
Updated: 2025/07/31

TRC

Product number: M294840
Product name: 2-Methyl-5-chloroindole
Packaging: 2.5g
Price: $140
Updated: 2021/12/16

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5-CHLORO-2-METHYLINDOLE Chemical Properties,Usage,Production

Chemical Properties

light pink to beige-pale brown crystalline powder

Uses

2-Methyl-5-chloroindole has been shown to depress brainstem and telencephalon serotonin for 3 days after 24 hours of being administered intraventricularly.Dyes and metabolites.

Synthesis Reference(s)

Journal of the American Chemical Society, 96, p. 5495, 1974 DOI: 10.1021/ja00824a028

Synthesis

81327-26-6

1075-35-0

In a 100 mL stainless steel autoclave, 1.09 g (5.1 mmol) of 5-chloro-2-nitrophenylacetone and 72 mg (4 mol%) of cyclopentadienyl ferric dicarbonyl (dimer) were added as a catalyst and 40 g of toluene as a solvent, and the system was protected by nitrogen. After displacing the atmosphere in the reactor three times (10 kgf/cm2 nitrogen each time), carbon monoxide gas was injected to a pressure of 30 kgf/cm2. The reaction mixture was stirred at 120 °C for 5 h. The reaction was completed by cooling to room temperature. Upon completion of the reaction, it was cooled to room temperature and the complete conversion of 5-chloro-2-nitrophenylacetone was confirmed by liquid chromatography analysis. Subsequently, the reaction mixture was post-treated and purified by silica gel column chromatographic separation to afford 0.79 g (94.0% yield) of the target product 5-chloro-2-methylindole.

References

[1] Patent: US2007/83053, 2007, A1. Location in patent: Page/Page column 7

5-CHLORO-2-METHYLINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-2-METHYLINDOLE Suppliers

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View Lastest Price from 5-CHLORO-2-METHYLINDOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-CHLORO-2-METHYLINDOLE 1075-35-0
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-07-07

Career Henan Chemical Co

Product: 5-CHLORO-2-METHYLINDOLE 1075-35-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-23

1075-35-0, 5-CHLORO-2-METHYLINDOLERelated Search:

Ethyl 5-chloro-2-indolecarboxylate Dorastine 5-CHLORO-2-METHYLINDOLE 5-Chloroindole-2-carboxylic acid 7-Chloro-4-methylindole 4,6-DICHLORO-2-METHYLINDOLE 5-Chloroindole ETHYL 5-CHLORO-3-PHENYL-1H-INDOLE-2-CARBOXYLATE 1H-INDOLE, 5-CHLORO-2-PHENYL- 4,5-dichloro-2-methyl-1h-indole 2-CHLORO-5,6,7,8,9,10-HEXAHYDROCYCLOHEPTA[B]INDOLE-6-CARBOXAMIDE 5-CHLORO-3-PHENYL-1H-INDOLE-2-CARBOXYLIC ACID 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE 5-CHLORO-2,3-DIMETHYL-1H-INDOLE 6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one 5-CHLORO-2-METHYLINDOLE-3-ACETIC ACID 6-CHLORO-1 2 3 4-TETRAHYDROCARBAZOLE 9& ETHYL 5-CHLORO-3-METHYL-1H-INDOLE-2-CARBOXYLATE

5-CHLORO-2-METHYLINDOLE

2-METHYL-5-CHLOROINDOLE

TIMTEC-BB SBB003903

RARECHEM AH BS 0087

5-CHLORO-2-METHYLINDOLE 97%

2-Methyl-5-chloro-1H-indole

5-Chloro-2-methylindole,95%

1H-Indole, 5-chloro-2-methyl-

5-Chloro-2-methyl-1H-indole

5-Chloro-2-Methylindole, 98.0%(GC&T

5-Chloro-2-methylindole &gt

1075-35-0

Simple Indoles

HALIDE

Indoles

Simple Indoles

Stains and Dyes

Stains&Dyes, A to