ChemicalBook > CAS DataBase List > 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.
70641-51-9
Chemical Name
1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
EDELFOSINE;ET-18-OCH3;ET-18-OCH?;Ro 14-5243;NSC 343649;NSC 324368;SN-ET-18-OCH3;18:0-1:0 DIETHER PC;2-O-METHYL PAF C-18;innersalt,4-oxide,(+-)-hydroxide
CBNumber
CB2768197
Molecular Formula
C27H58NO6P
Formula Weight
523.74
MOL File
70641-51-9.mol
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1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

storage temp. 
-20°C
solubility 
ethanol: 15 mg/mL at 45 °C, soluble
form 
waxy solid
color 
white
Water Solubility 
Soluble to 20 mM in water
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
YK0718000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0332
Product name
Edelfosine
Purity
≥95% (HPLC)
Packaging
5mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
341207
Product name
ET-18-OCH?
Packaging
5mg
Price
$144
Updated
2024/03/01
Sigma-Aldrich
Product number
O9262
Product name
1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine
Purity
≥99% (TLC), waxy solid
Packaging
5mg
Price
$141
Updated
2022/05/15
Sigma-Aldrich
Product number
SML0332
Product name
Edelfosine
Purity
≥95% (HPLC)
Packaging
25mg
Price
$568
Updated
2024/03/01
Usbiological
Product number
448513
Product name
ET-18-OCH3
Packaging
5mg
Price
$305
Updated
2021/12/16
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1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Uses

Edelfosine has been used to treat human lung carcinoma A549 cells and study its effects on tuftelin 1 (TUFT1) expression. It is also used to evaluate the cell growth of MCF-7/M cells.

Definition

ChEBI: 1-octadecyl-2-methylglycero-3-phosphocholine is a glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.

General Description

Edelfosine has anti-inflammatory, anti-autoimmune, antiparasitic and anti-viral properties. It stimulates eryptosis by cell shrinkage and cell membrane scrambling.

Biochem/physiol Actions

Edelfosine is a synthetic alkyl-lisophospholipid with anti-tumor activity. The compound induces apoptosis in a variety of cancer cells. Edelfosine accumulates in the cell membrane, where it alters lipid composition and induces the co-clustering of lipid rafts and Fas/CD95 death receptor.

storage

Store at -20°C

1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

China 6 Germany 1 Japan 1 Switzerland 3 The Netherlands 1 United Kingdom 2 United States 10 Global 24
Fluorochem Ltd
Tel
--
Fax
--
Email
vernam@fluorochem.co.uk
Country
United Kingdom
ProdList
6375
Advantage
65
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74

70641-51-9, 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:

1,2-DISTEAROYL-D70-3-SN-GLYCEROPHOSPHATIDYLCHOLINE 1-OCTADECANOYL-2-[(CIS,CIS,CIS,CIS)-5,8,11,14-EICOSATETRAENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-STEAROYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DINONADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE EDELFOSINE,1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-O-DIOCTADECYL-RAC-GLYCERO-3-PHOSPHOCHOLINE 1-stearoyl-2-linoleoylphosphatidylcholine 3-O-OCTADECYL-2-O-ACETYL-SN-GLYCERO-1-PHOSPHOCHOLINE 1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE PAF (C18) 1,2-DISTEAROYL-RAC-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-O-DIOCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine 1-O-OCTADECYL-2-PROPIONYL-SN-GLYCERO-3-PHOSPHOCHOLINE

  • 4-Hydroxy-7-methoxy-N,N,N-trimethyl-3,5,9-Trioxa-4-phosphaheptacosan-1-aminium 4-oxide
  • NSC 324368
  • NSC 343649
  • Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine
  • Ro 14-5243
  • ET-18-OCH?
  • ET-18-OCH3
  • EDELFOSINE
  • 18:0-1:0 DIETHER PC
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • ET-18-OCH - CAS 70641-51-9 - Calbiochem
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • 2-O-METHYL PAF C-18
  • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide
  • SN-ET-18-OCH3
  • 3,5,9-trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-7-methoxy-n,n,n-trimethyl
  • innersalt,4-oxide,(+-)-hydroxide
  • rac-1-octadecyl-2-methoxyglycero-3-phosphocholine
  • (2-methoxy-3-octadecoxy-propyl) 2-(trimethylazaniumyl)ethyl phosphate
  • (2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
  • (2-methoxy-3-stearyloxy-propyl) 2-(trimethylammonio)ethyl phosphate
  • Edelfosine, ALP, Ro 14-5243, ET-18-OMe, ET 18-OCH3, NSC 324368, NSC 343649
  • 1-Octadecyl-2-methylglycero-3-phosphorylcholine
  • 70641-51-9
  • C27H58NO6P