Methanesulfonamide

Product Name: Methanesulfonamide
CAS No.: 3144-09-0
Chemical Name: Methanesulfonamide
Synonyms: METHANSULFONAMIDE;Mesyl amide;METHYL SULFONAMIDE;METHANESULPHONAMIDE;Methanesulfonic amide;A sulfonaMide;METHYLSULFAMIDE;Methylsulfonamid;Methanesulfomide;Methansulfonamid
CBNumber: CB2776813
Molecular Formula: CH5NO2S
Formula Weight: 95.12
MOL File: 3144-09-0.mol

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Methanesulfonamide Property

Melting point:: 85-89 °C(lit.)
Boiling point:: 208.2±23.0 °C(Predicted)
Density: 1.229 (estimate)
refractive index: 1.5130 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Slightly soluble in DMSO and methanol.
pka: 10.87±0.60(Predicted)
form: Crystals, Powder or Flakes
color: White to yellow
BRN: 1740835
InChI: InChI=1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4)
InChIKey: HNQIVZYLYMDVSB-UHFFFAOYSA-N
SMILES: CS(N)(=O)=O
CAS DataBase Reference: 3144-09-0(CAS DataBase Reference)
NIST Chemistry Reference: Methane sulfonamide(3144-09-0)
EPA Substance Registry System: Methanesulfonamide (3144-09-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
TSCA: T
HazardClass: IRRITANT
HS Code: 29350090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 64275
Product name: Methanesulfonamide
Purity: ≥97.0% (CHN)
Packaging: 10g
Price: $93.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: 64275
Product name: Methanesulfonamide
Purity: ≥97.0% (CHN)
Packaging: 50g
Price: $151
Updated: 2025/07/31

TCI Chemical

Product number: M0915
Product name: Methanesulfonamide
Purity: >98.0%(N)
Packaging: 25g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: M0915
Product name: Methanesulfonamide
Purity: >98.0%(N)
Packaging: 100g
Price: $123
Updated: 2025/07/31

TCI Chemical

Product number: M0915
Product name: Methanesulfonamide
Purity: >98.0%(N)
Packaging: 500g
Price: $494
Updated: 2025/07/31

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Methanesulfonamide Chemical Properties,Usage,Production

Chemical Properties

White to yellow crystals, powder or flakes

Uses

Methanesulfonamide will react with thionyl chloride, cyanates, carbon disulfide and ketones and aldehydes to prepare pharmaceuticals, brightening agent and other target molecules. It is also used in biological studies to predict binding affinity and binding mode of protein ligand complexes.

Uses

Methanesulfonamide is used in the synthesis of important organic reagents such as N-(2-methylthio-1-p-toluenesufonyl)methanesulfonamide and tert-butyl ((2-(trimethylsilyl)ethyl)sulfonyl)carbamate.
It can be used as a source of nitrogen in the conversion of carboxylic acids to corresponding nitriles.
It is widely used as a reagent in the synthesis of medicinally important compounds such as derivatives of indole-N-acetamide, methanesulfonamide pyrimidine-substituted 3,5-dihydroxy-6-heptenoates and repertaxin.

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 4096, 1968 DOI: 10.1021/ja01017a032
The Journal of Organic Chemistry, 60, p. 7682, 1995 DOI: 10.1021/jo00128a048
Tetrahedron Letters, 35, p. 7201, 1994 DOI: 10.1016/0040-4039(94)85360-6

Toxics Screening Level

The initial threshold screening level (ITSL) for methanesulfonamide is 44 μg/m3 (annual averaging time).

Methanesulfonamide Preparation Products And Raw materials

Raw materials

Methanesulfonyl chloride

Preparation Products

Amsacrine N-(-Bromovaleryl)methanesulfonamide Fomesafen

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Methanesulfonamide Suppliers

Americas 1 Belgium 4 China 359 Europe 5 France 1 Germany 8 India 29 Japan 4 Malaysia 2 Romania 1 Russia 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 13 United States 38 Global 470

Cenik Chemicals

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Contract Chemicals Limited

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Manchester Organics

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Biosynth Carbosynth

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Apollo Scientific Ltd.

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Leancare Ltd.

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MOLEKULA Ltd.

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Eurolabs Limited

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Fluorochem Ltd

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Fluorochem Ltd.

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VWR International

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MDA Chemicals Ltd.

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Contract Chemicals, Ltd.

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View Lastest Price from Methanesulfonamide manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Methanesulfonamide 3144-09-0
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-06

Langfang Hawk Techology & Development Co, Ltd.

Product: Methanesulfonamide 3144-09-0
Price: US $0.00-0.00/Kg/Drum
Min. Order: 100g
Purity: ＞98.5%
Supply Ability: 20tons
Release date: 2019-07-05

Langfang Hawk Techology & Development Co, Ltd.

Product: Methanesulfonamide 3144-09-0
Price: US $0.00-0.00/Kg/Drum
Min. Order: 100g
Purity: ＞98.5%
Supply Ability: 20tons
Release date: 2019-07-05

3144-09-0, MethanesulfonamideRelated Search:

3-Aminobenzenesulfonamide Cyclopropanesulfonamide TRIFLUOROMETHANESULFONYL FLUORIDE Trifluoromethanesulfonamide Sulfamide Dimethyl sulfone Sodium carboxymethyl cellulose N,N-Dimethylformamide Sulfanilamide Benzenesulfonamide p-Toluenesulfonamide Ethanesulfonamide DANSYL HYDRAZINE N-Phenyl-bis(trifluoromethanesulfonimide) ACID VIOLET 5 TPCK 4-AMINOSULFONYL-1-HYDROXY-2-NAPHTHOIC ACID, 97 p-Toluenesulfonyl Isocyanate

Methylsulfonamid

METHYL SULFONYLAMINE

METHYL SULFONAMIDE

LABOTEST-BB LT00153664

Methanesulfonamide, 98+%

Methanesulphonamide,98+%

Mesyl amide

Methanesulfonyl amide

MethanesulfonaMid

Methanesulfomide

METHANSULFONAMIDE

METHANESULPHANAMIDE

METHANESULPHONAMIDE

METHANESULFONAMIDE

METHYLSULFAMIDE

Methanesulfonic amide

Methanesulphonamide 97%

A sulfonaMide

MethanesulfonaMide, 98% 25GR

Methanesulfonamide >=97.0% (CHN)

Methanesulfonamide&gt

Methanesulfonamide, 98%, for synthesis

Methansulfonamid

Methanesulfonamide (6CI, 7CI, 8CI, 9CI, ACI)

2-Phenoxy-phenyl methane sulphonamide

Selexipag Impurity 21

Metane Sulfoamide

3144-09-0

3I44-09-0

CH5NO2S

CH3SO2NH2

CH5O2NS

Building Blocks

Organic Building Blocks

Sulfur Compounds

Sulfonamides/Sulfinamides

Pharmaceutical Intermediates