ChemicalBook > CAS DataBase List > Dalbavancin hydrochloride

Dalbavancin hydrochloride

Product Name
Dalbavancin hydrochloride
CAS No.
2227366-51-8
Chemical Name
Dalbavancin hydrochloride
Synonyms
BI-397 hydrochloride;MDL-63397 hydrochloride;Dalbavancin Hydrochloride(Mixture)
CBNumber
CB28029346
Molecular Formula
C88H101Cl3N10O28
Formula Weight
1853.17
MOL File
2227366-51-8.mol
More
Less

Dalbavancin hydrochloride Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO: ≥ 24 mg/mL (12.95 mM)
form 
Solid
color 
White to light yellow
Water Solubility 
Water: 50 mg/mL (26.98 mM)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-3579
Product name
Dalbavancinhydrochloride
Purity
99.48%
Packaging
1mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-3579
Product name
Dalbavancinhydrochloride
Purity
99.48%
Packaging
5mg
Price
$180
Updated
2021/12/16
ChemScene
Product number
CS-3579
Product name
Dalbavancinhydrochloride
Purity
99.48%
Packaging
10mg
Price
$288
Updated
2021/12/16
ChemScene
Product number
CS-3579
Product name
Dalbavancinhydrochloride
Purity
99.48%
Packaging
25mg
Price
$528
Updated
2021/12/16
ChemScene
Product number
CS-3579
Product name
Dalbavancinhydrochloride
Purity
99.48%
Packaging
50mg
Price
$720
Updated
2021/12/16
More
Less

Dalbavancin hydrochloride Chemical Properties,Usage,Production

Biological Activity

Dalbavancin hydrochloride(MDL-63397 hydrochloride) is a semi-synthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits Staphylococcus aureus and Bacillus anthracis with MIC90 of 0.06 μg/mL and 0.25 μg/mL, respectively.

in vitro

Dalbavancin is a parenterally administered semisynthetic lipoglycopeptide developed to combat infections caused by resistant gram-positive pathogens. Dalbavancin exhibits potent in vitro bactericidal activity against gram-positive pathogens including S. aureus (MRSA ), VISA, and non-VanA strains of VRE. Dalbavancin is developed for the treatment of complicated skin and skin structure infections (cSSSIs), predominantly those caused by MRSA and β-hemolytic streptococci , organisms against which it has shown greater potency than existing glycopeptide therapeutic agents.

in vivo

Dalbavancin (15-240 mg/kg; intraperitoneal injection; every 36 h or 72 h; for 14 days; female BALB/c mice) treatment has a survival rate of 80% to 100% of mice with all dose regimens.

Animal Model: Female BALB/c mice (6-8 weeks) challenged with Ames strain of B . anthracis
Dosage: 15 mg/kg, 30 mg/kg, 60 mg/kg, 120 mg/kg, 240 mg/kg
Administration: Intraperitoneal injection ; every 36 h or 72 h; for 14 days
Result: The efficacy was 80 to 100%, as determined by the rate of survival at 42 days, when treatment was initiated 24 h postchallenge with regimens of 15 to 120 mg/kg every 36 h or 30 to 240 mg/kg every 72 h.

Dalbavancin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Dalbavancin hydrochloride Suppliers

China 43 United States 4 Global 47
Tel
027-61907345 13397111514
Fax
3443707954
Email
w13397111514@163.com
Country
China
ProdList
1010
Advantage
58
Tel
021-021-52919136 17315815539
Email
2804155403@qq.com
Country
China
ProdList
205
Advantage
58
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Tel
18622939839
Fax
QQ:343281693
Email
tjby921@163.com
Country
China
ProdList
510
Advantage
55
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
10270
Advantage
58
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Tel
027-83778895 18602735115
Fax
027-51119224
Email
18602735115@163.com
Country
China
ProdList
1993
Advantage
64
Tel
021-54285032 18116461626
Fax
021-54285032
Email
25493162@qq.com
Country
China
ProdList
142
Advantage
58
Tel
650-6922368
Email
sales@achemblock.com
Country
China
ProdList
2992
Advantage
58
Tel
027-027-52344656 15871722230
Fax
2796190295
Email
15871722230@163.com
Country
China
ProdList
4855
Advantage
58
Tel
400-880-2824 18107960669
Fax
18140514863
Email
79046690@qq.com
Country
China
ProdList
1267
Advantage
58
Tel
027-59207852 13308628970
Fax
QQ:2779667926
Email
buy@fortunachem.com
Country
China
ProdList
2793
Advantage
58
Tel
18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
3056
Advantage
58
Tel
400-880-2824; 13184580281
Fax
400-880-2824
Email
hj@ruiweier.cn
Country
China
ProdList
2737
Advantage
58
Tel
18502762009
Email
721846333@qq.com
Country
China
ProdList
2448
Advantage
58
Tel
027-81302411 15377658509
Email
zs@dkybpc.com
Country
China
ProdList
2196
Advantage
58
Tel
027-59102966 18717199209
Fax
027-59379337
Email
2853877583@qq.com
Country
China
ProdList
3522
Advantage
58
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62163
Advantage
58
Tel
400-880-2824 15608648206
Email
1987516016@qq.com
Country
China
ProdList
2811
Advantage
58
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Tel
4001650900 13817534909
Email
3003940895@qq.com
Country
China
ProdList
10720
Advantage
58
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29794
Advantage
58
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Tel
13003551299 13003551299
Email
2369399482@qq.com
Country
China
ProdList
7566
Advantage
58
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
Tel
4001-009266 17349750668
Email
product@sci-e.com
Country
China
ProdList
2808
Advantage
58
Tel
0512-65974739-0 15151475053
Email
mengqi_biopole@163.com
Country
China
ProdList
45
Advantage
58
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
Tel
19359985961 19359985961
Email
2430503320@qq.com
Country
China
ProdList
1469
Advantage
58
Tel
17721492509
Email
643638326@qq.com
Country
China
ProdList
5345
Advantage
58
Tel
19526384105
Email
3671394075@qq.com
Country
China
ProdList
2864
Advantage
58
Tel
027-59102966 18717199209
Email
2853877583@QQ.com
Country
China
ProdList
7850
Advantage
58
Tel
027-02759101766 13125137661
Email
2853877621@qq.com
Country
China
ProdList
5421
Advantage
58
Tel
18024082417
Email
market@ubiochem.com
Country
China
ProdList
9272
Advantage
58
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32957
Advantage
60
Tel
+86-020-81960175-617 +8615602392859
Email
Intermediate@cato-chem.com
Country
China
ProdList
8056
Advantage
58
Tel
+86-0512-83500002 +8615195660023
Email
sales@senfeida.com
Country
China
ProdList
23046
Advantage
58
Tel
+86-852-30606658
Email
market18@leapchem.com
Country
China
ProdList
43340
Advantage
58
Tel
+undefined18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
3135
Advantage
58
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6650
Advantage
58

2227366-51-8, Dalbavancin hydrochlorideRelated Search:

Antibiotic A 40926 DesvancosaMinyl VancoMycin Teicoplanin A2-4 Teicoplanin A2-5 A 40926 coMplex

  • BI-397 hydrochloride
  • MDL-63397 hydrochloride
  • Dalbavancin Hydrochloride(Mixture)
  • 2227366-51-8