Tucotuzumab Celmoleukin

Product Name: Tucotuzumab Celmoleukin
CAS No.: 339986-90-2
Chemical Name: Tucotuzumab Celmoleukin
Synonyms: Tucotuzumab;Tucotuzumab Celmoleukin;Tucotuzumab (anti-EpCAM);Research Grade Tucotuzumab;Research Grade Tucotuzumab (DHD17404)
CBNumber: CB28080785
Formula Weight: 0
MOL File: Mol file

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Tucotuzumab Celmoleukin Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Tucotuzumab Celmoleukin Chemical Properties,Usage,Production

Uses

Tucotuzumab (Anti-EPCAM Recombinant Antibody) is an antigen-specific IgG1 monoclonal antibody that targets human epithelial cell adhesion molecule (EpCAM). Tucotuzumab links two IL-2 molecules and is an immunosuppressant and anti-tumor active molecule[1].

in vivo

Tucotuzumab (75 μg; intratumoral injection; 5 daily of 15 μg (total dose of 75 μg), each in 50 μL PBS; on days 10 and 14) results in significantly greater tumor growth suppression and enhances survival^[1].

Animal Model:	Female Balb/c mice bearing CT26-KS colon adenocarcinoma^[1]
Dosage:	75 μg
Administration:	Intratumoral injection; 5 daily of 15 μg (total dose of 75 μg), each in 50 μL PBS; on days 10 and 14
Result:	Resulted in significantly greater tumor growth suppression and enhanced survival.

References

[1] Erik E Johnson, et al. Radiofrequency ablation combined with KS-IL2 immunocytokine (EMD 273066) results in an enhanced antitumor effect against murine colon adenocarcinoma. Clin Cancer Res. 2009 Aug 1;15(15):4875-84. DOI:10.1158/1078-0432.CCR-09-0110

Tucotuzumab Celmoleukin Preparation Products And Raw materials

Raw materials

Preparation Products

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Tucotuzumab Celmoleukin Suppliers

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339986-90-2, Tucotuzumab CelmoleukinRelated Search:

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Tucotuzumab Celmoleukin

Research Grade Tucotuzumab (DHD17404)

Tucotuzumab

Research Grade Tucotuzumab

Tucotuzumab (anti-EpCAM)

339986-90-2