5-METHOXY-PYRIDIN-2-YLAMINE
- Product Name
- 5-METHOXY-PYRIDIN-2-YLAMINE
- CAS No.
- 10167-97-2
- Chemical Name
- 5-METHOXY-PYRIDIN-2-YLAMINE
- Synonyms
- 5-METHOXYPYRIDIN-2-AMINE;2-Amino-5-methoxypyridine;5-methoxy-2-Pyridinamine;5-Methoxy-2-aMinopyridine;2-PyridinaMine,5-Methoxy-;2-Amine-5-methoxy-pyridine;5-METHOXY-PYRIDIN-2-YLAMINE;5-Methoxypyridin-2-aMine-HCl;Pyridine, 2-amino-5-methoxy-;2-Amino-5-methoxypyridine, >=97%
- CBNumber
- CB2839295
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 10167-97-2.mol
5-METHOXY-PYRIDIN-2-YLAMINE Property
- Melting point:
- 36-38 °C
- Boiling point:
- 128-1300C/10Torr
- Density
- 1.139±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Chloroform, Dichloromethane
- form
- Oil
- pka
- 3.57±0.10(Predicted)
- color
- Dark Red
- InChI
- InChI=1S/C6H8N2O/c1-9-5-2-3-6(7)8-4-5/h2-4H,1H3,(H2,7,8)
- InChIKey
- XJKJHILCYUUVSJ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=C(OC)C=C1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- CDS022493
- Product name
- 2-Amino-5-methoxypyridine
- Packaging
- 50 mg
- Price
- $107
- Updated
- 2025/07/31
- Product number
- A3168
- Product name
- 2-Amino-5-methoxypyridine
- Packaging
- 1G
- Price
- $114
- Updated
- 2025/07/31
- Product number
- A611959
- Product name
- 2-Amino-5-methoxypyridine
- Packaging
- 2g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- A611959
- Product name
- 2-Amino-5-methoxypyridine
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- A611959
- Product name
- 2-Amino-5-methoxypyridine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
5-METHOXY-PYRIDIN-2-YLAMINE Chemical Properties,Usage,Production
Chemical Properties
Dark Red Oil
Synthesis
76066-07-4
10167-97-2
General procedure for the synthesis of 2-amino-5-methoxypyridine from 2-bromo-3-methoxy-6-nitropyridine: 2-bromo-3-methoxy-6-nitropyridine (1.20 g, 5.15 mmol), hydrazine hydrate (6 mL), Pd/C (10%, 400 mg), and ethanol (40 mL) were mixed and heated to reflux for 45 minutes. Upon completion of the reaction, the mixture was allowed to cool and filtered through Celite. The filtrate was concentrated, water (20 mL) and saturated ammonia (10 mL) were added and extracted with chloroform (2 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated to give 2-amino-5-methoxypyridine as a colorless solid with a low melting point. Yield: 615 mg (96%).1H NMR (DMSO-d6, 400MHz) δ 7.64 (dd, 1H), 7.10 (dd, 1H), 6.42 (dd, 1H), 5.43 (br.s, 2H), 3.68 (s, 3H).
References
[1] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 57
[2] Patent: WO2007/51982, 2007, A1. Location in patent: Page/Page column 49
[3] Pharmazie, 2000, vol. 55, # 12, p. 907 - 912
[4] Journal of Medicinal Chemistry, 2009, vol. 52, # 3, p. 637 - 645
[5] Australian Journal of Chemistry, 1981, vol. 34, # 4, p. 927 - 932
5-METHOXY-PYRIDIN-2-YLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-METHOXY-PYRIDIN-2-YLAMINE manufacturers
- Product
- 5-METHOXY-PYRIDIN-2-YLAMINE 10167-97-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-25
- Product
- 5-METHOXY-PYRIDIN-2-YLAMINE 10167-97-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11