6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

Uses

Product Name: 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
CAS No.: 89466-18-2
Chemical Name: 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
Synonyms: 6-BROMO-2-METHOXYPYRIDIN-3-AMINE;EOS-60782;3-Amino-6-bromo-2-methoxypyridine;6-Bromo-2-methoxy-3-aminopyridine;3-Amino-2-Methoxy-6-Bromopyridine;3-Pyridinamine, 6-bromo-2-methoxy-;6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE;2-Bromo-6-methoxy-pyridin-3-ylamine;5,6-dibromo-2-methoxypyridin-3-amine;6-bromo-2-methoxy –pyridine -3-ylamine
CBNumber: CB3431801
Molecular Formula: C6H7BrN2O
Formula Weight: 203.04
MOL File: 89466-18-2.mol

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6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Property

Melting point:: 78-79 °C (sublm)
Boiling point:: 277.6±35.0 °C(Predicted)
Density: 1.622±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 1.81±0.10(Predicted)
Appearance: Light brown to brown Solid
InChI: InChI=1S/C6H7BrN2O/c1-10-6-4(8)2-3-5(7)9-6/h2-3H,8H2,1H3
InChIKey: HSVYYOLSYNEVSP-UHFFFAOYSA-N
SMILES: C1(OC)=NC(Br)=CC=C1N
CAS DataBase Reference: 89466-18-2

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Safety

Risk Statements: 20/21/22-37/38-48
Safety Statements: 22-26-7/8-36/37/39-45
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: A594540
Product name: 3-Amino-6-bromo-2-methoxypyridine
Packaging: 500mg
Price: $95
Updated: 2021/12/16

Apolloscientific

Product number: OR18103
Product name: 3-Amino-6-bromo-2-methoxypyridine
Packaging: 250mg
Price: $19
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: Y14769
Product name: 3-Amino-6-bromo-2-methoxypyridine
Packaging: 1g
Price: $25
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-9-Q1
Product name: 3-Amino-6-bromo-2-methoxypyridine
Packaging: 250mg
Price: $28
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA38696
Product name: 3-Amino-6-bromo-2-methoxypyridine
Packaging: 1g
Price: $50
Updated: 2021/12/16

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6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Chemical Properties,Usage,Production

Uses

3-Amino-2-methoxy-6-bromopyridine is an organic heterocyclic compound that can be used as a pharmaceutical intermediate.

Chemical Properties

Brown powder

Synthesis

20265-38-7

89466-18-2

2-Methoxypyridin-3-amine (39.4 g) was dissolved in N,N-dimethylformamide (200 mL) and the solution was cooled to -30 °C. A solution of N,N-dimethylformamide (100 mL) of N-bromosuccinimide (62.1 g) was slowly added dropwise with stirring. After the dropwise addition, the reaction was continued with stirring for 30 minutes. Subsequently, the reaction mixture was poured into water and extracted with chloroform. The organic layers were combined and washed sequentially with saturated sodium sulfite solution, water and brine. The organic layer was dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent ratio: hexane:ethyl acetate=9:1→4:1) to afford 6-bromo-2-methoxypyridin-3-amine as a yellow powder (51.9 g, 80% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3) and mass spectrometry: 1H NMR δppm 3.64-3.84 (m, 2H), 3.98 (s, 3H), 6.78 (dd, J=7.9,1.0 Hz, 1H), 6.87 (d, J=7.9 Hz, 1H); MS (+): 203 [M+H]+.

References

[1] Patent: US2011/237791, 2011, A1. Location in patent: Page/Page column 64
[2] Patent: WO2018/30550, 2018, A1. Location in patent: Paragraph 0648

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide Sodium chloride Sodium 3-Aminopyridine Carbon tetrachloride 1,4-Dioxane Diethyl ether Ammonium chloride Ethyl acetate Methanol Magnesium sulfate PETROLEUM ETHER

Preparation Products

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6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Suppliers

China 153 Germany 2 India 5 United Kingdom 2 United States 17 Global 179

Heze Bona Medical Technology Co., LTD

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Chiba Pharmaceutical Science and technology Co, Ltd.

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View Lastest Price from 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromo-2-methoxy-3-pyridinamine 89466-18-2
Price: US $2.00-6.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons
Release date: 2025-07-29

Shaanxi Dideu Medichem Co. Ltd

Product: 3-AMino-6-broMo-2-Methoxypyridine 89466-18-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2019-12-25

Dideu Industries Group Limited

Product: 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 89466-18-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-18

89466-18-2, 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINERelated Search:

2-Methoxypyridin-3-amine 5-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 5-Bromo-6-methoxy-pyridin-3-ylamine 3-AMINO-2-BROMO-6-METHOXYPYRIDINE 6-BROMO-5-METHOXY-PYRIDIN-2-YLAMINE 2-Bromo-6-hydroxypyridine 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 6-BROMO-2-METHOXY-3-NITRO-PYRIDINE 2-Bromo-6-methoxypyridine 3-AMINO-6-BROMO-PYRIDIN-2-OL

6-BROMO-2-METHOXYPYRIDIN-3-AMINE

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

6-Bromo-2-methoxy-3-aminopyridine

3-Amino-6-bromo-2-methoxypyridine

6-Bromo-2-methoxy-pyridin-3-ylamine ,97%

6-bromo-2-methoxy –pyridine -3-ylamine

2-Bromo-6-methoxy-pyridin-3-ylamine

3-PYRIDINE AMINE-6-BROMO-2-METHOXY (LR)

EOS-60782

3-Pyridinamine, 6-bromo-2-methoxy-

89466-18-2 3-AMino-6-broMo-2-Methoxypyridine

5,6-dibromo-2-methoxypyridin-3-amine

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE ISO 9001：2015 REACH

3-Amino-2-Methoxy-6-Bromopyridine

89466-18-2

189466-18-2