2-Bromo-6-hydroxypyridine
- Product Name
- 2-Bromo-6-hydroxypyridine
- CAS No.
- 27992-32-1
- Chemical Name
- 2-Bromo-6-hydroxypyridine
- Synonyms
- 6-Bromo-2-pyridone;2-Bromo-6-pyridinol;6-BROMOPYRIDIN-2-OL;6-Bromo-2-pyridinol;6-Bromopyridine-2-ol;Furfural Impurity 11;6-bromo-1H-pyridin-2-one;6-Bromopyridin-2(1H)-one;6-Bromo-2(1H)-pyridinone;2-BROMO-6-HYDROXYPYRIDINE
- CBNumber
- CB1291670
- Molecular Formula
- C5H4BrNO
- Formula Weight
- 174
- MOL File
- 27992-32-1.mol
2-Bromo-6-hydroxypyridine Property
- Melting point:
- 121.0 to 125.0 °C
- Boiling point:
- 336.6±42.0 °C(Predicted)
- Density
- 1.776±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 7.33±0.10(Predicted)
- color
- White to Light yellow to Purple
- InChI
- InChI=1S/C5H4BrNO/c6-4-2-1-3-5(8)7-4/h1-3H,(H,7,8)
- InChIKey
- VOMMPWVMVDGZEM-UHFFFAOYSA-N
- SMILES
- C1(=O)NC(Br)=CC=C1
- CAS DataBase Reference
- 27992-32-1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B4408
- Product name
- 6-Bromo-2-hydroxypyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- B4408
- Product name
- 6-Bromo-2-hydroxypyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $152
- Updated
- 2025/07/31
- Product number
- B698853
- Product name
- 6-Bromopyridin-2-ol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 076485
- Product name
- 2-Bromo-6-hydroxypyridine
- Purity
- 95+%
- Packaging
- 25g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- FB140276
- Product name
- 6-Bromopyridin-2-ol
- Packaging
- 10g
- Price
- $323.8
- Updated
- 2021/12/16
2-Bromo-6-hydroxypyridine Chemical Properties,Usage,Production
Synthesis Reference(s)
Synthesis, p. 707, 1974 DOI: 10.1055/s-1974-23407
Synthesis
626-05-1
27992-32-1
General procedure for the synthesis of 2-bromo-6-hydroxypyridine from 2,6-dibromopyridine: 2,6-dibromopyridine (4 g, 17 mmol), potassium tert-butoxide (20 g, 0.27 mol), and redistilled tert-butanol (100 mL) were mixed and reacted at reflux overnight. After completion of the reaction, the mixture was cooled and the solvent was removed under vacuum. Subsequently, the ice-water mixture was carefully added and the aqueous layer was extracted with chloroform (100 mL x 2) to remove unreacted starting material. Next, the aqueous layer was acidified with 3N hydrochloric acid and again extracted with chloroform (100 mL x 2). The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated to give pure 2-bromo-6-hydroxypyridine (2.5 g, 85% yield) as a white solid.
References
[1] Patent: US2009/318455, 2009, A1. Location in patent: Page/Page column 82
[2] Synlett, 2015, vol. 26, # 11, p. 1557 - 1562
[3] Patent: WO2014/57103, 2014, A1. Location in patent: Page/Page column 174
[4] Tetrahedron, 1996, vol. 52, # 35, p. 11385 - 11404
[5] Tetrahedron, 1996, vol. 52, # 35, p. 11385 - 11404
2-Bromo-6-hydroxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-6-hydroxypyridine manufacturers
- Product
- 2-Bromo-6-hydroxypyridine 27992-32-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-12
- Product
- 2-Bromo-6-hydroxypyridine 27992-32-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-24
- Product
- 2-Bromo-6-hydroxypyridine 27992-32-1
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 MT
- Release date
- 2020-07-28