ChemicalBook > CAS DataBase List > 2-Bromo-6-hydroxypyridine

2-Bromo-6-hydroxypyridine

Product Name
2-Bromo-6-hydroxypyridine
CAS No.
27992-32-1
Chemical Name
2-Bromo-6-hydroxypyridine
Synonyms
6-Bromo-2-pyridone;2-Bromo-6-pyridinol;6-BROMOPYRIDIN-2-OL;6-Bromo-2-pyridinol;6-Bromopyridine-2-ol;Furfural Impurity 11;6-bromo-1H-pyridin-2-one;6-Bromopyridin-2(1H)-one;6-Bromo-2(1H)-pyridinone;2-BROMO-6-HYDROXYPYRIDINE
CBNumber
CB1291670
Molecular Formula
C5H4BrNO
Formula Weight
174
MOL File
27992-32-1.mol
More
Less

2-Bromo-6-hydroxypyridine Property

Melting point:
121.0 to 125.0 °C
Boiling point:
336.6±42.0 °C(Predicted)
Density 
1.776±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
7.33±0.10(Predicted)
color 
White to Light yellow to Purple
InChI
InChI=1S/C5H4BrNO/c6-4-2-1-3-5(8)7-4/h1-3H,(H,7,8)
InChIKey
VOMMPWVMVDGZEM-UHFFFAOYSA-N
SMILES
C1(=O)NC(Br)=CC=C1
CAS DataBase Reference
27992-32-1
More
Less

Safety

HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B4408
Product name
6-Bromo-2-hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$39
Updated
2025/07/31
TCI Chemical
Product number
B4408
Product name
6-Bromo-2-hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$152
Updated
2025/07/31
TRC
Product number
B698853
Product name
6-Bromopyridin-2-ol
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
076485
Product name
2-Bromo-6-hydroxypyridine
Purity
95+%
Packaging
1g
Price
$24
Updated
2021/12/16
AK Scientific
Product number
W5092
Product name
2-Bromo-6-hydroxypyridine
Packaging
1g
Price
$34
Updated
2021/12/16
More
Less

2-Bromo-6-hydroxypyridine Chemical Properties,Usage,Production

Synthesis Reference(s)

Synthesis, p. 707, 1974 DOI: 10.1055/s-1974-23407

Synthesis

626-05-1

27992-32-1

General procedure for the synthesis of 2-bromo-6-hydroxypyridine from 2,6-dibromopyridine: 2,6-dibromopyridine (4 g, 17 mmol), potassium tert-butoxide (20 g, 0.27 mol), and redistilled tert-butanol (100 mL) were mixed and reacted at reflux overnight. After completion of the reaction, the mixture was cooled and the solvent was removed under vacuum. Subsequently, the ice-water mixture was carefully added and the aqueous layer was extracted with chloroform (100 mL x 2) to remove unreacted starting material. Next, the aqueous layer was acidified with 3N hydrochloric acid and again extracted with chloroform (100 mL x 2). The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate and concentrated to give pure 2-bromo-6-hydroxypyridine (2.5 g, 85% yield) as a white solid.

References

[1] Patent: US2009/318455, 2009, A1. Location in patent: Page/Page column 82
[2] Synlett, 2015, vol. 26, # 11, p. 1557 - 1562
[3] Patent: WO2014/57103, 2014, A1. Location in patent: Page/Page column 174
[4] Tetrahedron, 1996, vol. 52, # 35, p. 11385 - 11404
[5] Tetrahedron, 1996, vol. 52, # 35, p. 11385 - 11404

2-Bromo-6-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Bromo-6-hydroxypyridine Suppliers

Americas 1 China 155 Europe 1 France 1 Germany 1 India 6 Japan 1 The Netherlands 1 United Kingdom 1 United States 18 Global 186
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
More
Less

View Lastest Price from 2-Bromo-6-hydroxypyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Bromo-6-hydroxypyridine 27992-32-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-12
Dideu Industries Group Limited
Product
2-Bromo-6-hydroxypyridine 27992-32-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-24
Shaanxi Dideu Medichem Co. Ltd
Product
2-Bromo-6-hydroxypyridine 27992-32-1
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
100 MT
Release date
2020-07-28

27992-32-1, 2-Bromo-6-hydroxypyridineRelated Search:

Chromium picolinate 2-Chloro-3-cyanopyridine 1-Hexadecylpyridinium bromide 3-Bromoanisole 3-Hydroxypyridine 2-BROMO-6-CHLOROPYRIDINE 2,6-Lutidine 2-Bromo-4-Hydroxypyridine 2-Bromo-6-methoxypyridine 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 2-BROMO-3-HYDROXYPYRIDINE,2-BROMO-3-HYDROXYPYRIDINE 97%,2-Bromo-3-pyridinol(2-Bromo-3-hydroxypyridine),2-BROMO-3-HYDROXYPYRIDINE (2-BROMO-3-PYRIDINOL) 2-BROMO-5-HYDROXYPYRIDINE ,98%,6-BROMO-3-HYDROXYPYRIDINE,2-BROMO-5-HYDROXYPYRIDINE 6-BROMO-2-METHOXY-3-NITRO-PYRIDINE 2-Bromo-6-tert-butylOXY-pyridine 3-AMINO-6-BROMO-PYRIDIN-2-OL 3-AMINO-2-BROMO-6-METHOXYPYRIDINE Bromine 2-Bromo-6-propoxypyridine

  • 2-BROMO-6-HYDROXYPYRIDINE
  • 6-BROMOPYRIDIN-2-OL
  • 2-Bromo-6-pyridinol
  • 6-BROMOPYRIDINE-2-OL, 98+%
  • 6-Bromo-2-hydroxypyridine
  • 6-Bromopyridin-2(1H)-one
  • 6-Bromopyridine-2-ol
  • 6-Bromo-2-pyridone
  • 6-bromo-1H-pyridin-2-one
  • 6-Bromopyridin-2(1H)-One(WX637131)
  • 6-Hydroxy-2-bromopyridine
  • 6-Bromo-2(1H)-pyridinone
  • 6-bromo-1,2-dihydropyridin-2-one
  • 6-Bromo-2-hydroxypyridine &gt
  • 2(1H)-Pyridinone, 6-bromo-
  • 6-Bromo-2-pyridinol
  • 2-Bromo-6-hydroxypyridine ISO 9001：2015 REACH
  • Furfural Impurity 11
  • 27992-32-1
  • Heterocycle-Pyridine series
  • alcohol|alkyl bromide
  • Pyridine Series
  • Pyridine