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Epinastine hydrobromide

Application
Product Name
Epinastine hydrobromide
CAS No.
127786-29-2
Chemical Name
Epinastine hydrobromide
Synonyms
EPINASTIN HBR;Epinastine HBr;Epinastine-13C-d3 HBr;Epinastin hydrobromide;epinastine hydrobromide;9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrobromide;9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine monohydrobromide;(+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide;6-Aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine (E)-2-butenedioate Epinastine hydrobromide
CBNumber
CB2854847
Molecular Formula
C16H16BrN3
Formula Weight
330.22234
MOL File
127786-29-2.mol
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Epinastine hydrobromide Property

Melting point:
284-286°
storage temp. 
Sealed in dry,Room Temperature
InChI
InChI=1S/C16H15N3.BrH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H
InChIKey
ADPMHRDERZTFIN-UHFFFAOYSA-N
SMILES
N12C(N)=NCC1C1C=CC=CC=1CC1C=CC=CC2=1.Br
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E589593
Product name
EpinastinHbr
Packaging
50mg
Price
$75
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0025691
Product name
EPINASTINE HYDROBROMIDE
Purity
95.00%
Packaging
5MG
Price
$505.47
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0025691
Product name
EPINASTINE HYDROBROMIDE
Purity
95.00%
Packaging
1G
Price
$1274.7
Updated
2021/12/16
Alichem
Product number
127786292
Product name
9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-aminehydrobromide
Packaging
1g
Price
$568
Updated
2021/12/16
Crysdot
Product number
CD31004008
Product name
9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-aminehydrobromide
Purity
95+%
Packaging
1g
Price
$705
Updated
2021/12/16
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Epinastine hydrobromide Chemical Properties,Usage,Production

Application

Clinical studies have shown that, at the same dosage, epinastine hydrochloride is significantly more effective than other second-generation histamine H1 receptor antagonists such as terfenadine, astamiva, and ketotifen, and also has a lower incidence of central sedation and cardiotoxicity. Therefore, the market demand for epinastine hydrochloride is substantial, making its synthesis necessary. Literature searches reveal that publicly available patents and literature use 6-aminomethyl-6,11-dihydro-5H-dibenzo[b,e]azapyridine (Ⅳ) as a key intermediate in epinastine synthesis, which is cyclized with cyanogen bromide to yield epinastine. Epinastine hydrobromide is also a synthetic intermediate for epinastine.

Epinastine hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Epinastine hydrobromide manufacturers

Career Henan Chemical Co
Product
Epinastine hydrobromide 127786-29-2
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100g , 1kg, 5kg , 50kg
Release date
2020-01-07

127786-29-2, Epinastine hydrobromideRelated Search:


  • Epinastine-13C-d3 HBr
  • (+/-)-3-amino-9,13b-dihydro-1h-dibenz[c,f]imidazo[1,5-a]azepine hydrobromide
  • EPINASTIN HBR
  • Epinastine HBr
  • 9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrobromide
  • epinastine hydrobromide
  • Epinastin hydrobromide
  • 6-Aminomethyl-6,11-dihydro-5H-dibenz[b,e]azepine (E)-2-butenedioate Epinastine hydrobromide
  • 9,13b-dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3-amine monohydrobromide
  • 127786-29-2
  • C16H15N3HBr