Iothalamate meglumine

Product Name: Iothalamate meglumine
CAS No.: 13087-53-1
Chemical Name: Iothalamate meglumine
Synonyms: Cysto-Conray;EINECS 235-998-9;Meglumine conray;Meglumine iotalamate;Iothalamate Meglumine;N-Methylglucamine salt;Iotalamic acid meglumine;Iothalamic acid·meglumine;Methylglucamine iotalamate;Iotalamic acid meglumine salt
CBNumber: CB2921013
Molecular Formula: C11H9I3N2O4.C7H17NO5
Formula Weight: 809.115
MOL File: 13087-53-1.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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Iothalamate meglumine Chemical Properties,Usage,Production

Originator

Conray,Mallinckrodt Inc.,US,1962

Uses

Diagnostic aid (radiopaque medium).

Definition

ChEBI: Iothalamate meglumine is an amidobenzoic acid.

Manufacturing Process

Crude 5-amino-2,4,6-triiodo-N-methylisophthalamic acid (21.0 g) was dissolved in warm dimethylacetamide (40 ml) and acetic anhydride (30 ml) and concentrated sulfuric acid (2 drops) were added. This solution was heated on the steam bath for 2 hours, then heated at 110°C for 5 minutes, then cooled. Water and ammonium hydroxide were added to destroy the excess acetic anhydride, after which the mixture was evaporated to a volume of 50 ml. The cooled solution was acidified with concentrated hydrochloric acid and a tan solid was collected. The crude product was dissolved in 100 ml of water containing a slight excess of sodium hydroxide. The pH was adjusted to 4.5 with acetic acid, and the solution was treated with charcoal. The colorless solution was acidified with concentrated hydrochloric acid and cooled, and the precipitate was filtered off and dried under reduced pressure. The resulting 5- acetamido-2,4,6-triiodo-N-methylisophthalamic acid decomposes about 285°C and does not melt below 300°C.
5-acetamido-2,4,6-triiodo-N-methylisophthalamic acid was slurried in water and dissolved by the addition of an equivalent quantity of N-methylglucamine. The solution was evaporated to dryness to yield the meglumate salt of 5- acetamido-2,4,6-triiodo-N-methylisophthalamic acid.

brand name

Conray(Mallinckrodt).

Therapeutic Function

Diagnostic aid (radiopaque medium)

General Description

Iothalamate meglumineis a high-osmolar, ionic monomer with 47% boundiodine content. Conray is indicated for use in angiography,excretory urography, arthrography, cholangiography, endoscopicretrograde cholangiopancreatography, and variousCT procedures.

Iothalamate meglumine Preparation Products And Raw materials

Raw materials

Preparation Products

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Iothalamate meglumine Suppliers

China 8 Germany 1 United States 3 Global 12

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15352
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-89586680 +86-18192503167
Fax: +86-29-88380327
Email: 1026@dideu.com
Country: China
ProdList: 7724
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 31121
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11974
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 19704
Advantage: 58

Tel: 4008-099-669
Email: 23419001name@qq.com
Country: CHINA
ProdList: 73043
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TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

13087-53-1, Iothalamate meglumineRelated Search:

Closantel Glucosamine Cyclic adenosine monophosphate Meglumine Iotalamic acid 5-AMINO-N-METHYLISOPHTHALAMIC ACID 2-IODO-5-METHYLBENZOIC ACID 2-IODO-3-METHYLBENZOIC ACID D-Glucammonium, N-(3-acetamido-5-(methylcarbamoyl)-2,4,6-triiodobenzyl )-N-(2,3-dihydroxypropyl)-N-methyl-, (3-acetamido-5-methylcarbamoyl-2, 4,6-triiodo)-, benzoate 4-IODO-3-METHYLBENZOIC ACID 5-Amino-2,4,6-triiodo-N-methylisophthalamic Acid Iothalamate meglumine

Iothalamate Meglumine

D-Glucitol, 1-deoxy-1-(methylamino)-, 3-(acetylamino)-2,4,6-triiodo- 5-[(methylamino)carbonyl]benzoate (salt)

1-deoxy-1-(methylamino)-D-glucitol 3-(acetylamino)-2,4,6-triiodo-5-[(methylamino)carbonyl]benzoate

N-Methylglucamine salt

iothalamic acid meglumine salt

Iothalamic acid·meglumine

Meglumine iotalamate

Meglumine iothalamate injection

Iotalamic acid meglumine salt

Iothalamate meglumine USP/EP/BP

Iotalamic acid meglumine

Cysto-Conray

EINECS 235-998-9

Meglumine conray

Methylglucamine iotalamate

13087-53-1

Organics