Davercin
- Product Name
- Davercin
- CAS No.
- 55224-05-0
- Chemical Name
- Davercin
- Synonyms
- erythromycin A cyclic 11,12-carbonate;CWE;DAVERCIN;Dravercin;Davercin USP/EP/BP;Erythromycin cycloester;Eritromicina A carbonato;Erythromycin Impurity 10;Erythromycin Impurity 50;Erythromycin Cyclocarbonate
- CBNumber
- CB2966540
- Molecular Formula
- C38H65NO14
- Formula Weight
- 759.93
- MOL File
- 55224-05-0.mol
Davercin Property
- Melting point:
- >135°C (dec.)
- Boiling point:
- 859.8±65.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- pka
- 13.49±0.70(Predicted)
- form
- Solid
- color
- White
Safety
- Toxicity
- LD50 oral in rat: 5800mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 21348
- Product name
- Davercin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $67
- Updated
- 2024/03/01
- Product number
- 21348
- Product name
- Davercin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $199
- Updated
- 2024/03/01
- Product number
- 21348
- Product name
- Davercin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $332
- Updated
- 2024/03/01
- Product number
- 21348
- Product name
- Davercin
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $746
- Updated
- 2024/03/01
- Product number
- E650045
- Product name
- ErythromycinCyclocarbonate
- Packaging
- 2.5mg
- Price
- $110
- Updated
- 2021/12/16
Davercin Chemical Properties,Usage,Production
Description
Davercin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It has broad-spectrum activity against various Gram-positive and Gram-negative bacteria (MICs = 0.02-50 μg/ml). Davercin is non-toxic to mice and rats (LD50s = 4.05 and 5.9 g/kg, respectively). Formulations containing davercin have been used to treat a variety of urogenital bacterial infections.
Uses
Davercin (erythromycin A cyclic 11,12-carbonate) is a first generation semi-synthetic erythromycin. Davercin is prepared by coupling the 11- and 12-OH groups to form a cyclic carbonate. This simple modification improves the stability and hydrophobicity of the macrocyclic structure. Davercin shows comparable or better in vitro potency, low host toxicity and improved pharmacokinetics compared with erythromycin.
Uses
Erythromycin Cyclocarbonate is a derivative of Erythromycin (E649950), an antibcterial agent working on the 50S ribosomal subunit.
Definition
ChEBI: Davercin is an aminoglycoside.
Davercin Preparation Products And Raw materials
Raw materials
Preparation Products
Davercin Suppliers
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- 400-6009262 16621234537
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- 021-64823266
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- Country
- China
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- 14113
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- 1-631-485-4226; 16314854226
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- United States
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- 010-56205725
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- 010-65763397
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- China
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- 025-66099280 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
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- China
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- 19918
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- 55
- Tel
- +1 (866) 930-6790
- Fax
- +1 (866) 333-9607
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- United States
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- 021-33632979 15002134094
- Fax
- 021-33632979
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- +86-13439059536 +86-15201677815
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- 0755-0755-66853366 13670046396
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- 0755-28363542
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- China
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- 021-61350663 13052117465
- Fax
- 021-61350662
- sales@zehanbiopharma.com
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- China
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- 990
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- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
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View Lastest Price from Davercin manufacturers
- Product
- Davercin 55224-05-0
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-07
- Product
- Davercin 55224-05-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-22
- Product
- Davercin 55224-05-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 784
- Release date
- 2019-09-02