4-Morpholineethanesulfonic acid

ChemicalBook > CAS DataBase List > 4-Morpholineethanesulfonic acid

4-Morpholineethanesulfonic acid

Application

Product Name: 4-Morpholineethanesulfonic acid
CAS No.: 4432-31-9
Chemical Name: 4-Morpholineethanesulfonic acid
Synonyms: MES;2-(N-MORPHOLINO)ETHANESULFONIC ACID;2-MORPHOLINOETHANESULFONIC ACID;MES 2-Morpholinoethanesulfonic acid;ME1;TIMTEC-BB;2-(N-Morpholino)ethanesulfonic;4-MORPHOLINOETHANESULFONIC ACID;MKS1;BBS13
CBNumber: CB3100297
Molecular Formula: C6H13NO4S
Formula Weight: 195.24
MOL File: 4432-31-9.mol

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4-Morpholineethanesulfonic acid Property

Melting point:: >300 °C(lit.)
Boiling point:: 102°C
Density: 1.208 (estimate)
refractive index: 1.5500 (estimate)
storage temp.: 2-8°C
solubility: H₂O: 0.5 M at 20 °C, clear
form: Powder
pka: pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011
color: White
PH: 2.5-4.0 (25℃ in neat)
PH Range: 5.5 - 6.7
Water Solubility: 185.2g/L at 20℃
λmax: λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 13,5929
BRN: 6350956
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: SXGZJKUKBWWHRA-UHFFFAOYSA-N
LogP: -2.2 at 20℃
CAS DataBase Reference: 4432-31-9(CAS DataBase Reference)
EPA Substance Registry System: 4-Morpholineethanesulfonic acid (4432-31-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25-22
WGK Germany: 1
RTECS: QE9104530
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 76039
Product name: MES solution
Purity: BioUltra, for molecular biology, 0.5?M in H2O
Packaging: 100ML
Price: $206
Updated: 2024/03/01

Sigma-Aldrich

Product number: 475893
Product name: MES, Free Acid, ULTROL® Grade
Purity: A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
Packaging: 100G
Price: $115
Updated: 2024/03/01

Sigma-Aldrich

Product number: 76039
Product name: MES solution
Purity: BioUltra, for molecular biology, 0.5?M in H2O
Packaging: 500ML
Price: $818
Updated: 2024/03/01

Sigma-Aldrich

Product number: 475893
Product name: MES, Free Acid, ULTROL® Grade
Purity: A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
Packaging: 500G
Price: $561
Updated: 2024/03/01

Sigma-Aldrich

Product number: 475893
Product name: MES, Free Acid, ULTROL® Grade
Purity: A zwitterionic buffer useful in the pH range of 5.5-6.5. Has a pKa of 6.10 at 25°C. Absorbance (1.0 M, H2O, 260 nm):0.05.
Packaging: 1KG
Price: $787
Updated: 2024/03/01

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4-Morpholineethanesulfonic acid Chemical Properties,Usage,Production

Application

4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.

Chemical Properties

White/clear crystalline powder

Uses

MES solution has been used to activate microspheres. It has also been used as a component of activating solution to activate carboxyl groups of poly lactic-co-glycolic acid (PLGA).

Uses

Biological buffer.

Definition

ChEBI: 2-(N-morpholino)ethanesulfonic acid is a Good's buffer substance, pKa = 6.15 at 20 ℃. It is an organosulfonic acid and a MES. It is a conjugate acid of a 2-(N-morpholino)ethanesulfonate. It is a tautomer of a 2-(N-morpholiniumyl)ethanesulfonate.

General Description

MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.

Flammability and Explosibility

Not classified

storage

Store at RT

Purification Methods

Crystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.]

4-Morpholineethanesulfonic acid Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Sodium sulfite Sulfur trioxide METHYL LAURATE LARD Methyl palmitate

Preparation Products

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View Lastest Price from 4-Morpholineethanesulfonic acid manufacturers

Henan Fengda Chemical Co., Ltd

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $8.00-2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-24

Hebei Yanxi Chemical Co., Ltd.

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $20.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20mt/mon
Release date: 2023-09-05

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 3500kg/month
Release date: 2021-09-09

4432-31-9, 4-Morpholineethanesulfonic acidRelated Search:

Tridemorph Moroxydine Moroxydine hydrochloride Dimethomorph Ethanesulfonic acid Ascoric Acid MES monohydrate 2-methylthioadenosine-5’-o-diphosphate(2-mes-atp),sodiumsal HEPPS MES-K,MES POTASSIUM SALT,2-(N-Morpholino)ethanesulfonic acid potassium salt, 4-Morpholineethanesulfonic acid potassium salt 2-(N-Morpholino)ethanesulfonic acid hemisodium salt MES sodium salt 2-methylthioadenosine-5’-o-triphosphate(2-mes-atp),sodiumsal Methyl ethanesulfonate OVA IN MES MesBuffer 4-Morpholineethanesulfonic acid monohydrate, MES-d13,MES-d13,4-Morpholineethanesulfonic acid monohydrate, MES-d13 4-Morpholineethanesulfonic acid

MES 2-Morpholinoethanesulfonic acid

MES(2-(n-Morpholino)-ethanesulfonic acid), Free Acid

BBS13

FLJ20345

MKS1

ANTI-ME1 antibody produced in mouse

HUMNDME

ME1

TIMTEC-BB

EZNA CYCLE-PURE KIT (V-SPIN)

MES BUFFERED SALINE

MES

2-(N-MORPHOLINO)ETHANESULFONIC ACID

2-(N-MORPHOLINO)ETHANESULPHONIC ACID

2-MORPHOLINOETHANESULFONIC ACID

2-(4-Morpholino)ethanesulphonic acid

MES 2-(N-Morpholino)ethanesulfonic acid

mes free acid hydrate

mes free acid molecular biology

mes free acid plant cell culture tested

MES, Free Acid, ULTROL Grade

MES, Molecular Biology Grade 2-(N-Morpholino)ethanesulfonic acid, Molecular Biology Grade

2-morpholinoethanesulphonic acid

MES 1M SOLUTION, BIOTECHNOLOGY PERFORMAN

CHIP BUFFER B, STRINGENT

MES FREE ACID LOW MOISTURE CONTENT

MES FREE ACID MONOHYDRATE SIGMAULTRA

MES HYDRAT

MES BUFFER SOLUTION 0.5M

MES SODIUM, BIOTECHNOLOGY PERFORMANCE CE RTIFIED

MES FREE ACID, BIOTECHNOLOGY PERFORMANCE CERTIFIED

2-(N-MORPHOLINO)ETHANESULFONIC ACID (MES)

MorpholinoethaneSulfonicAcid(Mes)

2-(4-MORPHOLINO)ETHANESULFONIC ACID

4-MORPHOLINOETHANESULFONIC ACID

4-MORPHOLINEETHANESULFONIC ACID

2-(4-Morpholinyl)ethanesulfonic acid

2-Morpholin-4-ylethanesulfonic acid

4-(2-Sulfoethyl)morpholine

MES【Dotite】

MES,99%,<1% water

4-Morpholinethanesulfonic acid

Ethanesulfonic acid, 2-morpholino-

Morpholineethanesulfonic acid

Morpholino-N-ethylsulfonate

MORPHOLINOETHANE SULFONICACID (MES) ANALYTICAL GRADE

MES, <1% water, 99%

MES hydrate,2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid

MES,2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid

4-Morpholineethanesu

2-Morpholinoethanesulfonic Acid(MES)

MES, Anhydrous, Biological Buffer

MES anhydrous (2-Morpholinoethan sulfonic acid)

MES hydrate, 99+%

2-Morpholinoethanesulfonic acid hydrate (MES)

Mes Buffer Anhydrous

2-Morpholineethanesulfonic acid

2-(N-Morpholino)ethanesulfonic acid, 99.5%, molecular biology