ChemicalBook > CAS DataBase List > 4-Morpholineethanesulfonic acid

4-Morpholineethanesulfonic acid

Application

Product Name: 4-Morpholineethanesulfonic acid
CAS No.: 4432-31-9
Chemical Name: 4-Morpholineethanesulfonic acid
Synonyms: MES;2-(N-MORPHOLINO)ETHANESULFONIC ACID;2-MORPHOLINOETHANESULFONIC ACID;MES 2-Morpholinoethanesulfonic acid;ME1;TIMTEC-BB;2-(N-Morpholino)ethanesulfonic;4-MORPHOLINOETHANESULFONIC ACID;MKS1;BBS13
CBNumber: CB3100297
Molecular Formula: C6H13NO4S
Formula Weight: 195.24
MOL File: 4432-31-9.mol

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4-Morpholineethanesulfonic acid Property

Melting point:: >300 °C(lit.)
Boiling point:: 102°C
Density: 1.208 (estimate)
refractive index: 1.5500 (estimate)
storage temp.: 2-8°C
solubility: H₂O: 0.5 M at 20 °C, clear
form: Powder
pka: pKa at 0.1M ionic: 0°, 6.38; 20°, 6.15; 37°, 5.98; pKa1 1.99; pKa2 6.21; pKa/°C -0.011
color: White
PH: 2.5-4.0 (25℃ in neat)
PH Range: 5.5 - 6.7
Water Solubility: 185.2g/L at 20℃
λmax: λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 13,5929
BRN: 6350956
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: SXGZJKUKBWWHRA-UHFFFAOYSA-N
LogP: -2.2 at 20℃
CAS DataBase Reference: 4432-31-9(CAS DataBase Reference)
EPA Substance Registry System: 4-Morpholineethanesulfonic acid (4432-31-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25-22
WGK Germany: 1
RTECS: QE9104530
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M1442
Product name: MOPS solution
Purity: BioPerformance Certified, 1 M, suitable for cell culture
Packaging: 100 mL
Price: $56.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: M1442
Product name: MOPS solution
Purity: BioPerformance Certified, 1 M, suitable for cell culture
Packaging: 500 mL
Price: $167.61
Updated: 2025/07/31

Sigma-Aldrich

Product number: M1442
Product name: MOPS solution
Purity: BioPerformance Certified, 1 M, suitable for cell culture
Packaging: 1 L
Price: $299.54
Updated: 2025/07/31

Sigma-Aldrich

Product number: M1317
Product name: MES solution
Purity: suitable for, BioPerformance Certified, 1?M, suitable for cell culture
Packaging: 100ML
Price: $65.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: M1317
Product name: MES solution
Purity: suitable for, BioPerformance Certified, 1?M, suitable for cell culture
Packaging: 500ML
Price: $188
Updated: 2025/07/31

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4-Morpholineethanesulfonic acid Chemical Properties,Usage,Production

Application

4-Morpholineethanesulfonic acid (MES) is one of the good′s buffers, and the most extensively application is biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring and it does not form complexes with the majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes. MES has been also used as a component of the elution buffer used to elute plasma from α2-macroglobulin affinity column. It has been used as an activation buffer during antibody conjugation to microparticles and it has been used in the functionalization of microchannels during the creation of microfluidic-integrated surface plasmon resonance (SPR) platform for pathogen detection.

Chemical Properties

White/clear crystalline powder

Uses

MES solution has been used to activate microspheres. It has also been used as a component of activating solution to activate carboxyl groups of poly lactic-co-glycolic acid (PLGA).

Uses

Biological buffer.

Definition

ChEBI: 2-(N-morpholino)ethanesulfonic acid is a Good's buffer substance, pKa = 6.15 at 20 ℃. It is an organosulfonic acid and a MES. It is a conjugate acid of a 2-(N-morpholino)ethanesulfonate. It is a tautomer of a 2-(N-morpholiniumyl)ethanesulfonate.

General Description

MES is one of the Good′s buffers, the most extensively used biological buffers. MES is a zwitterionic N-substituted aminosulfonic acid with a morpholinic ring. It does not form complexes with majority of the metals used in environmental and biological studies. It is easily soluble in water and has minimum lipid solubility, making it impermeable to membranes.

Flammability and Explosibility

Not classified

storage

Store at RT

Purification Methods

Crystallise MES from hot EtOH containing a little water. The picrate crystallises from EtOH and has m 178.8-182o. [Malkiel & Mason J Org Chem 8 199 1943, Beilstein 27 III/IV 370.]

4-Morpholineethanesulfonic acid Preparation Products And Raw materials

Raw materials

Sodium hypochlorite Sodium sulfite Sulfur trioxide METHYL LAURATE LARD Methyl palmitate

Preparation Products

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View Lastest Price from 4-Morpholineethanesulfonic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 3500kg/month
Release date: 2021-09-09

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $100.00-75.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-20

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Morpholineethanesulfonic acid 4432-31-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-25

4432-31-9, 4-Morpholineethanesulfonic acidRelated Search:

Tridemorph Moroxydine Moroxydine hydrochloride Dimethomorph Ethanesulfonic acid Ascoric Acid MES monohydrate 2-methylthioadenosine-5’-o-diphosphate(2-mes-atp),sodiumsal HEPPS MES-K,MES POTASSIUM SALT,2-(N-Morpholino)ethanesulfonic acid potassium salt, 4-Morpholineethanesulfonic acid potassium salt 2-(N-Morpholino)ethanesulfonic acid hemisodium salt MES sodium salt 2-methylthioadenosine-5’-o-triphosphate(2-mes-atp),sodiumsal Methyl ethanesulfonate OVA IN MES 4-Morpholineethanesulfonic acid monohydrate, MES-d13,MES-d13,4-Morpholineethanesulfonic acid monohydrate, MES-d13 MesBuffer 4-Morpholineethanesulfonic acid

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MES(2-(n-Morpholino)-ethanesulfonic acid), Free Acid

BBS13

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TIMTEC-BB

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MES

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2-(N-MORPHOLINO)ETHANESULFONIC ACID (MES)

MorpholinoethaneSulfonicAcid(Mes)

2-(4-MORPHOLINO)ETHANESULFONIC ACID

4-MORPHOLINOETHANESULFONIC ACID

4-MORPHOLINEETHANESULFONIC ACID

2-(4-Morpholinyl)ethanesulfonic acid

2-Morpholin-4-ylethanesulfonic acid

4-(2-Sulfoethyl)morpholine

MES【Dotite】

MES,99%,<1% water

4-Morpholinethanesulfonic acid

Ethanesulfonic acid, 2-morpholino-

Morpholineethanesulfonic acid

Morpholino-N-ethylsulfonate

MORPHOLINOETHANE SULFONICACID (MES) ANALYTICAL GRADE

MES, <1% water, 99%

MES hydrate,2-(N-Morpholino)ethanesulfonic acid hydrate, 4-Morpholineethanesulfonic acid

MES,2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid

4-Morpholineethanesu

2-Morpholinoethanesulfonic Acid(MES)

MES anhydrous (2-Morpholinoethan sulfonic acid)

MES hydrate, 99+%

2-Morpholinoethanesulfonic acid hydrate (MES)

2-Morpholineethanesulfonic acid

2-(N-Morpholino)ethanesulfonic acid, 99.5%, molecular biology

2-(morpholin-4-yl)ethane-1-sulfonic acid

4-Morpholineethanesulfonic acid 4432-31-9

4432-31-9 4-Morpholineethanesulfonic acid MES

MES, ≥99%(T),water≤1.0%

MES, ≥99.5%(T)