ChemicalBook > CAS DataBase List > BEPOTASTINE

BEPOTASTINE

Product Name: BEPOTASTINE
CAS No.: 125602-71-3
Chemical Name: BEPOTASTINE
Synonyms: BEPOTASTINE;Bestatin (i.e;Bepotastine >(S)-Bepotastine;Bepotastine >90%;betotastine besilate;Bepotastine free base;-4-(4-((4-Chlorophenyl);(190786-43-7) bepotastine;Bepotastine, 10 mM in DMSO
CBNumber: CB3102554
Molecular Formula: C21H25ClN2O3
Formula Weight: 388.89
MOL File: 125602-71-3.mol

Less

BEPOTASTINE Property

Melting point:: 56 - 58°C
Boiling point:: 546.8±50.0 °C(Predicted)
Density: 1.26
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 4.44±0.10(Predicted)
form: Solid
color: White to Pale Beige

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: B316095
Product name: Bepotastine>90%
Packaging: 5mg
Price: $115
Updated: 2021/12/16

ChemScene

Product number: CS-M1828
Product name: Bepotastine
Purity: 98.12%
Packaging: 100mg
Price: $248
Updated: 2021/12/16

ChemScene

Product number: CS-M1828
Product name: Bepotastine
Purity: 98.12%
Packaging: 250mg
Price: $498
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007090
Product name: BEPOTASTINE
Purity: 95.00%
Packaging: 5MG
Price: $501.71
Updated: 2021/12/16

ChemScene

Product number: CS-M1828
Product name: Bepotastine
Purity: 98.12%
Packaging: 1g
Price: $900
Updated: 2021/12/16

Less

BEPOTASTINE Chemical Properties,Usage,Production

Uses

Bepotastine is a histamine H1 receptor antagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).

Definition

ChEBI: An ether that is (S)-(4-chlorophenyl)(pyridin-2-yl)methanol in which the hydroxyl hydrogen is substituted by a 1-(3-carboxypropyl)piperidin-4-yl group. A topical, selective and non-sedating histamine (H1) receptor anta onist used (as its benzenesulfonate salt) for treatment of itching associated with allergic conjunctivitis.

in vivo

Bepotastine (10 g/L; eye drop; 3 times at intervals of 20 min in one eye) demonstrates significant inhibition of PAF-induced conjunctival eosinophil infiltration^[1].
Bepotastine (3 mg/kg; p.o.; once) suppresses scratching behavior to a frequency of 59.0 and a duration of 14.57 seconds, which are almost the same levels compares with the control^[3].
Bepotastine (10 mg/kg; p.o.; once) significantly suppresses serum LTB 4 levels to 711.3 pg/mL at 1 h and 858.8 pg/mL at 2 h in NC/Nga mice with a rash^[3].

Animal Model:	Guinea pigs (6-week-old)^[1].
Dosage:	10 g/L (1.0% (w/v)) for 10 μL.
Administration:	Eye drop; 3 times at intervals of 20 min (in one eye).
Result:	Inhibited PAF-induced conjunctival eosinophil infiltration.

Animal Model:	Male BALB/c mice(12-week-old); NC/Nga mice^[3].
Dosage:	3, 10 mg/kg
Administration:	Oral administration; once (1 h before induces scratching behavior of Male BALB/c mice).
Result:	Significantly inhibited histamine-mediated scratching behavior in male BALB/c mice. Significantly suppressed serum LTB 4 levels in NC/Nga mice with a rash.

IC 50

H₁ Receptor

BEPOTASTINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

BEPOTASTINE Suppliers

China 96 India 8 United States 8 Global 112

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16077
Advantage: 64

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Beijing Lianben Pharm-Chemicals Tech. Co., Ltd

Tel: +86-10-83386766
Fax: +86-10-83386758
Email: sales@lianben.com
Country: China
ProdList: 91
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3120
Advantage: 55

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Suzhou Huihe Pharmaceutical Co. Ltd.

Tel: 86-0512-88819360,88985990
Fax: 86-0512-86876095
Email: asynderm@163.com
Country: China
ProdList: 90
Advantage: 60

SPIRO PHARMA

Tel
Fax: -
Email: eric_feng1954@126.com
Country: China
ProdList: 9248
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai QianYan Bio-technology Co., Ltd

Tel: 02781293128
Email: orders@biochemsafebuy.com
Country: China
ProdList: 9923
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Tube Pharmaceutical Co., Ltd.

Tel: 021-54338626 18017892860
Fax: 021-54338626
Email: sales@tubepharm.com
Country: China
ProdList: 2572
Advantage: 58

Alchemist-pharm chemical Technology Co. Ltd.

Tel: 0371-67991738 13783628208
Fax: QQ 412703949
Email: carl@alchemist-pharm.com
Country: China
ProdList: 1872
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4181
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Shandong Zhishang New Material Co., Ltd.

Tel: +8617653113209
Email: sales002@sdzschem.com
Country: China
ProdList: 3049
Advantage: 58

Baoji Guokang Healthchem Co., Ltd.

Tel: +86-0917-3909592 +86-13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9209
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15109
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Hahui (Shanghai) Pharmaceutical Technology Co., Ltd.

Tel: 021-13472633-721 13472633721
Email: 454407203@qq.com
Country: China
ProdList: 552
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1168
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988941452
Fax: QQ：3283937693
Email: YN_research@163.com
Country: China
ProdList: 3011
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

ShangHai Anpel Co, Ltd.

Tel: 18501792038 18502138905
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9611
Advantage: 58

Nanjing shengyilai Chemical Co., Ltd

Tel: 19951936396
Email: 3158688292@qq.com
Country: China
ProdList: 4856
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10001
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4171
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shenzhen Shengda Pharmaceutical co Limited

Tel: 0755-85269922 13424394241
Fax: QQ:1799060443
Email: sales@shengdapharm.com
Country: China
ProdList: 505
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815987 13927875076
Fax: 0751-2828607
Email: 3007432263@qq.com
Country: China
ProdList: 9963
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

Less

View Lastest Price from BEPOTASTINE manufacturers

Moxin Chemicals

Product: Bepotastine 125602-71-3
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95
Supply Ability: 10000000
Release date: 2025-02-13

Zibo Hangyu Biotechnology Development Co., Ltd

Product: bepotastine 125602-71-3
Price: US $70.00-700.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-31

Zhuozhou Wenxi import and Export Co., Ltd

Product: BEPOTASTINE 125602-71-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

125602-71-3, BEPOTASTINERelated Search:

BEPOTASTINE BESILATE (R)-7-(3-Aminohexahydro-1H-azepin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid Dapoxetine Lercanidipine Donepezil Posaconazole alpha-(4-chlorophenyl)pyridine-2-methanol BEPOTASTINE

4-(4-[(1S)(4-CHLOROPHENYL)-2-PYRIDYLMETHOXY]PIPERIDYL)BUTANOIC ACID

1-Piperidinebutanoic acid, 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-

betotastine besilate

4-[4-[(4-Chlorophenyl)pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid

(+)-(S)-4-[4-[1-(4-chlorophenyl)-1-(2-pyridyl)methoxy]piperidin-1-yl]butyric acid

4-[(S)-(4-chlorophenyl)-2-pyridinylMethoxy]-

-4-(4-((4-Chlorophenyl)

BEPOTASTINE

(190786-43-7) bepotastine

Bepotastine free base

Bepotastine &gt

Bepotastine >90%

Bepotastine D4Q: What is Bepotastine D4 Q: What is the CAS Number of Bepotastine D4 Q: What is the storage condition of Bepotastine D4 Q: What are the applications of Bepotastine D4

(S)-Bepotastine

Bestatin (i.e

Bepotastine, 10 mM in DMSO

125602-71-3