Methyl carbamate Property

Melting point:

56-58 °C (lit.)

Boiling point:

176-177 °C (lit.)

Density 

1,14 g/cm³

refractive index 

1.4125

Flash point:

93 °C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

700 g/L (20°C)

pka

13.37±0.50(Predicted)

form 

Adhering Crystals

color 

White

PH

6-8 (50g/l, H2O, 20℃)

Water Solubility 

700 g/L (20 ºC)

Sensitive 

Moisture Sensitive

Merck 

14,6036

BRN 

635779

CAS DataBase Reference

598-55-0(CAS DataBase Reference)

IARC

3 (Vol. 12, Sup 7) 1987

NIST Chemistry Reference

Carbamic acid, methyl ester(598-55-0)

EPA Substance Registry System

Methyl carbamate (598-55-0)

Safety

Hazard Codes 

Xn,T

Risk Statements 

36-40-61

Safety Statements 

26-36/37-36-22-45-53

WGK Germany 

3

RTECS 

FC2450000

TSCA 

Yes

HS Code 

29241900

Hazardous Substances Data

598-55-0(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

Methyl carbamate Chemical Properties,Usage,Production

Chemical Properties

Methyl carbamate is a white, adhesive crystal. It is highly soluble in water, as well as in ethanol, acetone, and other organic solvents.

Uses

Methyl carbamate was used in the synthesis of protected aminocyclopropanes.

Preparation

Methyl carbamate was synthesized by the following preparation. MDI (5.00 g,0.020mol) and 100 ml of dried acetone were weighed into a Ng-filled three-neck flask.Methanol (5 g, an excess amount) is added dropwise to the stirred MDI solution in the flask,and then the solution was heated to 56 C. After 24 hrs， the reaction mixture was cooled down to room temperature and evaporated to give a crude solid at about 100% yield. The following recrystallization procedure gave 3.1 g of a white solid (0.012 mol，60% yield). The disappearance of FT-IR stretching band of the isocyanate group (-N=C=O, 2280 cm') confirmed that the reaction was complete.

Definition

ChEBI: Methyl carbamate is a carbamate ester resulting from the formal condensation of the carboxy group of carbamic acid with methanol.

General Description

Methyl carbamate appears as white to Almost white powder to crystal. It an intermediate in the manufacture of dimethylol methyl carbamate-based resins, which are used in the textile industry as durable-press fabric finishes for polyester/cotton blends.

Air & Water Reactions

Water soluble.

Reactivity Profile

Methyl carbamate is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.

Fire Hazard

Flash point data for Methyl carbamate are not available; however, Methyl carbamate is probably combustible.

Safety Profile

Poison by ingestion and intraperitoneal routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also CARBAMATES.

Purification Methods

Crystallise the carbamate from *benzene or distil it. [Beilstein 3 H 21.]