Methyl 2-bromo-6-chlorobenzoate
- Product Name
- Methyl 2-bromo-6-chlorobenzoate
- CAS No.
- 685892-23-3
- Chemical Name
- Methyl 2-bromo-6-chlorobenzoate
- Synonyms
- EOS-61701;Methyl 2-acetyl-6-chlorobenzoate;Benzoic acid, 2-bromo-6-chloro-, methyl ester;Methyl 2-bromo-6-chlorobenzoate ISO 9001：2015 REACH
- CBNumber
- CB31117582
- Molecular Formula
- C8H6BrClO2
- Formula Weight
- 249.49
- MOL File
- 685892-23-3.mol
Methyl 2-bromo-6-chlorobenzoate Property
- Melting point:
- 54-56°
- Boiling point:
- 274.5±20.0 °C(Predicted)
- Density
- 1.604±0.06 g/cm3(Predicted)
- Flash point:
- 110°
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M295995
- Product name
- Methyl2-bromo-6-chlorobenzoate
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- M295995
- Product name
- Methyl2-bromo-6-chlorobenzoate
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- M295995
- Product name
- Methyl2-bromo-6-chlorobenzoate
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J96513
- Product name
- Methyl2-bromo-6-chlorobenzoate
- Packaging
- 1g
- Price
- $53
- Updated
- 2021/12/16
- Product number
- J96513
- Product name
- Methyl2-bromo-6-chlorobenzoate
- Packaging
- 10g
- Price
- $320
- Updated
- 2021/12/16
Methyl 2-bromo-6-chlorobenzoate Chemical Properties,Usage,Production
Uses
Methyl 2-bromo-6-chlorobenzoate
Synthesis
93224-85-2
74-88-4
685892-23-3
GENERAL STEPS: 2-bromo-6-chlorobenzoic acid (9.5 g, 0.041 mol) and potassium carbonate (8.6 g, 0.061 mol) were sequentially added to 50 mL of N,N-dimethylformamide and stirred until completely dissolved. Subsequently, iodomethane (11.2 g, 0.081 mol) was slowly added dropwise over 10 minutes. After the dropwise addition, the reaction mixture was continued to be stirred at room temperature for 3.5 hours. Upon completion of the reaction, the reaction mixture was diluted with 500 mL of water and back-extracted with ethyl acetate (3 x 300 mL). The organic phases were combined, washed with 1 M aqueous hydrochloric acid (100 mL), dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to afford methyl 2-bromo-6-chlorobenzoate (10.0 g, 99.4% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.413 (d, J = 8 Hz, 1H), 7.29 (d, J = 8 Hz, 1H), 7.137 (t, J = 8 Hz, 1H), 3.9 (s, 3H).
References
[1] Patent: US2014/256734, 2014, A1. Location in patent: Paragraph 0238-0240
[2] Journal of the American Chemical Society, 2015, vol. 137, # 13, p. 4445 - 4452
[3] Organic Process Research and Development, 2005, vol. 9, # 6, p. 764 - 767
Methyl 2-bromo-6-chlorobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-bromo-6-chlorobenzoate Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
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View Lastest Price from Methyl 2-bromo-6-chlorobenzoate manufacturers
- Product
- Methyl 2-bromo-6-chlorobenzoate 685892-23-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 200kgs/month
- Release date
- 2021-11-20
- Product
- Methyl 2-bromo-6-chlorobenzoate 685892-23-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-12