2-FLUORO-5-NITROPHENOL
- Product Name
- 2-FLUORO-5-NITROPHENOL
- CAS No.
- 22510-08-3
- Chemical Name
- 2-FLUORO-5-NITROPHENOL
- Synonyms
- 2-FLUORO-5-NITROPHENOL;Phenol, 2-fluoro-5-nitro-;2-Fluoro-5-nitrophenol 97%;2-Fluoro-5-nitrophenol, >=98%;4-Fluoro-3-hydroxynitrobenzene;1-fluoro-2-(Methyloxy)-4-nitrobenzene;2-FLUORO-5-NITROPHENOL ISO 9001：2015 REACH
- CBNumber
- CB31119283
- Molecular Formula
- C6H4FNO3
- Formula Weight
- 157.1
- MOL File
- 22510-08-3.mol
2-FLUORO-5-NITROPHENOL Property
- Boiling point:
- 256.7±25.0 °C(Predicted)
- Density
- 1.511±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Powder
- pka
- 6.95±0.19(Predicted)
- Appearance
- Yellow to brown Solid
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2908990000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F597628
- Product name
- 2-Fluoro-5-nitrophenol
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- F597628
- Product name
- 2-Fluoro-5-nitrophenol
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- J94991
- Product name
- 2-Fluoro-5-nitrophenol
- Packaging
- 1g
- Price
- $12
- Updated
- 2021/12/16
- Product number
- PC5009
- Product name
- 2-Fluoro-5-nitrophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 4654-3-38
- Product name
- 2-Fluoro-5-nitrophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
2-FLUORO-5-NITROPHENOL Chemical Properties,Usage,Production
Uses
2-Fluoro-5-nitrophenol
Synthesis
454-16-0
22510-08-3
General procedure for the synthesis of 2-fluoro-5-nitrophenol from 2-fluoro-5-nitroanisole: 116 ml (116 mmol) of boron tribromide (1 M dichloromethane solution) was added slowly dropwise to 5.00 g (29.2 mmol) of 1-fluoro-2-methoxy-4-nitrobenzene solution over 1 h at -10 °C, and the rate of the dropwise acceleration was controlled so that the reaction temperature did not exceed -5 °C. After completion of the reaction, the reaction solution was stirred at 0°C for 5 hours. Subsequently, the reaction was quenched by slow addition of 600 ml of ice water and diluted with 100 ml of ethyl acetate. After separation of the organic phase, the aqueous phase was extracted twice with ethyl acetate. All organic phases were combined and dried with anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure. The residue was purified by silica gel column chromatography (eluent ratio 10:1 cyclohexane/ethyl acetate) to afford 1.45 g (30% yield) of the target product 2-fluoro-5-nitrophenol. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6, δ/ppm): 10.99 (s, 1H), 7.78 (dd, 1H), 7.73 (ddd, 1H), 7.44 (dd, 1H).HPLC analysis (Method 1): retention time Rt = 3.60 min. Mass spectrum (DCI, m/z): 174 (M + NH4)+.
References
[1] Patent: US2010/298293, 2010, A1. Location in patent: Page/Page column 39
2-FLUORO-5-NITROPHENOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-FLUORO-5-NITROPHENOL manufacturers
- Product
- 2-FLUORO-5-NITROPHENOL 22510-08-3
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26
- Product
- 2-Fluoro-5-nitrophenol 22510-08-3
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100 tons
- Release date
- 2020-01-10
- Product
- 2-FLUORO-5-NITROPHENOL 22510-08-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11