3-Fluoro-4-bromobenzyl bromide
- Product Name
- 3-Fluoro-4-bromobenzyl bromide
- CAS No.
- 127425-73-4
- Chemical Name
- 3-Fluoro-4-bromobenzyl bromide
- Synonyms
- 3-Fluoro-4-bromobenzyl bromide;4-Bromo-3-fluorobenzylbromide,96%;4-Bromo-3-fluorobenzyl bromide 97%;3-Fluoride-4-Bromine Bromine Benzyl;4-BroMo-1-(broMoMethyl)-3-fluorobenzene;1-bromo-4-(bromomethyl)-2-fluorobenzene;Benzene, 1-bromo-4-(bromomethyl)-2-fluoro-;1-Bromo-4-(bromomethyl)-2-fluorobenzene, alpha,4-Dibromo-3-fluorotoluene
- CBNumber
- CB31130468
- Molecular Formula
- C7H5Br2F
- Formula Weight
- 267.92
- MOL File
- 127425-73-4.mol
3-Fluoro-4-bromobenzyl bromide Property
- Melting point:
- 33-36℃
- Boiling point:
- 252℃
- Density
- 1.923
- Flash point:
- 106℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- crystalline needles
- color
- White
Safety
- HazardClass
- 8
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B692158
- Product name
- 4-Bromo-3-fluorobenzylbromide
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB37123
- Product name
- 4-Bromo-3-fluorobenzyl bromide
- Packaging
- 2g
- Price
- $78.2
- Updated
- 2021/12/16
- Product number
- J98321
- Product name
- 4-Bromo-3-fluorobenzylbromide
- Packaging
- 4x25g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- FB37123
- Product name
- 4-Bromo-3-fluorobenzyl bromide
- Packaging
- 5G
- Price
- $125
- Updated
- 2021/12/16
- Product number
- PC5721
- Product name
- 4-Bromo-3-fluorobenzylbromide
- Purity
- 97%
- Packaging
- 25g
- Price
- $138
- Updated
- 2021/12/16
3-Fluoro-4-bromobenzyl bromide Chemical Properties,Usage,Production
Chemical Properties
light yellow liquid
Materials Uses
3-Fluoro-4-bromobenzyl bromide (4BFBB) is an organic compound that is a member of the class of halogenated aromatic compounds. This molecule has a set of isomers, which are in the same family and have the same chemical formula but different arrangements of atoms. 4BFBB has been used as an acceptor material for organic solar cells with experimental success. It absorbs light in the visible spectrum and transfers electrons to pbdb-t, increasing the efficiency of solar cells. The fluorine atoms in 4BFBB interact with other molecules due to their high electronegativity, making them useful for chemical reactions.
Synthesis
452-74-4
127425-73-4
General procedure for the synthesis of 3-fluoro-4-bromobenzyl bromide from 3-fluoro-4-bromotoluene: To a reaction flask was added a solution of 4-bromo-3-fluorotoluene (21.5 g, 0.114 mol) in acetonitrile (200 ml), followed by N-bromosuccinimide (NBS; 21.2 g, 0.119 mol). The mixture was heated to reflux and dibenzoyl peroxide (1.4 g, 0.004 mol) was added as initiator and the reaction was kept at reflux for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with water. The aqueous phase was separated and discarded, the organic phase was washed with saturated brine and dried over anhydrous sodium sulfate. Finally, the solvent was removed by vacuum concentration to afford the target product 3-fluoro-4-bromobenzyl bromide as an oil (27.1 g, 90% yield).
References
[1] Patent: WO2011/15287, 2011, A2. Location in patent: Page/Page column 13
[2] Patent: US2011/39934, 2011, A1. Location in patent: Page/Page column 5
[3] Patent: EP2700643, 2014, A1. Location in patent: Paragraph 0234
[4] Journal of Medicinal Chemistry, 2011, vol. 54, # 7, p. 2293 - 2306
[5] Journal of Medicinal Chemistry, 2005, vol. 48, # 18, p. 5705 - 5720
3-Fluoro-4-bromobenzyl bromide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Fluoro-4-bromobenzyl bromide manufacturers
- Product
- 3-Fluoro-4-bromobenzyl bromide 127425-73-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2020-01-16
- Product
- 3-Fluoro-4-bromobenzyl bromide 127425-73-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-28