2-Bromo-1-(bromomethyl)-4-fluorobenzene
- Product Name
- 2-Bromo-1-(bromomethyl)-4-fluorobenzene
- CAS No.
- 61150-57-0
- Chemical Name
- 2-Bromo-1-(bromomethyl)-4-fluorobenzene
- Synonyms
- 2-BroMo-1-(broMoMeth;2-Bromo-4-Fluorobenzyl;2-Bromo-4-fluorobenzene;2-BROMO-4-FLUOROBENZYL BROMIDE;2-Bromo-4-fluorobenzylbromide,96%;2-Bromine-4-Fluoride Bromine Benzyl;2-BROMO-1-(BROMOMETHYL)-4-FLUOROBENZENE;Benzene, 2-bromo-1-(bromomethyl)-4-fluoro-;2-Bromo-1-(bromomethyl)-4-fluorobenzene, alpha,2-Dibromo-4-fluorotoluene
- CBNumber
- CB8190648
- Molecular Formula
- C7H5Br2F
- Formula Weight
- 267.92
- MOL File
- 61150-57-0.mol
2-Bromo-1-(bromomethyl)-4-fluorobenzene Property
- Boiling point:
- 254.0±25.0 °C(Predicted)
- Density
- 1.923±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- Appearance
- Off-white to light yellow Crystal
- CAS DataBase Reference
- 61150-57-0(CAS DataBase Reference)
Safety
- RIDADR
- 3261
- HazardClass
- 8
- PackingGroup
- Ⅲ
- HS Code
- 2903998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
- Precautionary statements
-
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B692133
- Product name
- 2-Bromo-4-fluorobenzylbromide
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB68070
- Product name
- 2-Bromo-4-fluorobenzyl bromide
- Packaging
- 5G
- Price
- $50
- Updated
- 2021/12/16
- Product number
- W7343
- Product name
- 2-Bromo-4-fluorobenzylbromid
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- PC1236
- Product name
- 2-Bromo-4-fluorobenzylbromide
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 1700-B-30
- Product name
- 2-Bromo-4-fluorobenzyl bromide
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
2-Bromo-1-(bromomethyl)-4-fluorobenzene Chemical Properties,Usage,Production
Chemical Properties
white crystal powde
Synthesis
1422-53-3
61150-57-0
General procedure for the synthesis of 2-bromo-4-fluorobenzyl bromide from 2-bromo-4-fluorotoluene: In a round-bottomed flask equipped with a reflux condenser, 2-bromo-4-fluorotoluene (15 g, 79.3 mmol), N-bromosuccinimide (18.08 g, 101.6 mmol) and 2,2'-azobisisobutyronitrile (3.9 g, 23.8 mmol) were dissolved in carbon tetrachloride (150 mL). The reaction mixture was heated to reflux for 21 hours. After completion of the reaction, the mixture was cooled and the solvent was removed by distillation under reduced pressure. The crude product was suspended in dichloromethane and the organic layer was washed with water. Subsequently, the organic layer was washed with saturated aqueous sodium chloride solution and dried with anhydrous sodium sulfate. After filtration, the solvent was removed by distillation under reduced pressure to obtain the crude product. Purification of the crude product by column chromatography (eluent: 1% hexane solution of ethyl acetate tapered to 10% hexane solution of ethyl acetate) afforded 2-bromo-4-fluorobenzyl bromide as an oily white solid (18.5 g, 87% yield).GC-MS analysis showed m/z 268 [M]+.
References
[1] Synlett, 2011, # 17, p. 2525 - 2528
[2] Patent: WO2008/144223, 2008, A2. Location in patent: Page/Page column 28
[3] Patent: WO2007/70041, 2007, A1. Location in patent: Page/Page column 126
[4] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 409 - 416
[5] Collection of Czechoslovak Chemical Communications, 1999, vol. 64, # 4, p. 649 - 672
2-Bromo-1-(bromomethyl)-4-fluorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-1-(bromomethyl)-4-fluorobenzene Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2816
- Advantage
- 64
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
View Lastest Price from 2-Bromo-1-(bromomethyl)-4-fluorobenzene manufacturers
- Product
- 2-Bromo-1-(bromomethyl)-4-fluorobenzene 61150-57-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-11
- Product
- 2-Bromo-4-fluorobenzylbromide 61150-57-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-11-11
- Product
- 2-Bromo-1-(bromomethyl)-4-fluorobenzene 61150-57-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2020-01-16