ChemicalBook > CAS DataBase List > Demethyl-Coclaurine

Demethyl-Coclaurine

Product Name
Demethyl-Coclaurine
CAS No.
5843-65-2
Chemical Name
Demethyl-Coclaurine
Synonyms
Norcoclaurine;(RS)-norcoclaurine;1-(4-Hydroxybenzyl);Demethyl-Coclaurine;Higenamine - natural;DL-Demethylcoclaurine;HigenaMine HydrobroMide Salt;Demethyl-Coclaurine USP/EP/BP;Higenamine, 98%, from Lindera aggregata (Sims) Kosterm.;1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
CBNumber
CB31178446
Molecular Formula
C16H17NO3
Formula Weight
271.31
MOL File
5843-65-2.mol
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Demethyl-Coclaurine Property

Melting point:
208-210 °C
Boiling point:
522.4±50.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.72±0.40(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FH145240
Product name
Higenamine - natural
Packaging
2mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH145240
Product name
Higenamine - natural
Packaging
5mg
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH145240
Product name
Higenamine - natural
Packaging
10mg
Price
$150
Updated
2021/12/16
AK Scientific
Product number
9556AF
Product name
Higenamine
Packaging
5mg
Price
$185
Updated
2021/12/16
ChemScene
Product number
CS-0018527
Product name
Higenamine
Packaging
5mg
Price
$198
Updated
2021/12/16
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Demethyl-Coclaurine Chemical Properties,Usage,Production

Uses

(±)-Norcoclaurine can be used to prevent and treat of Alzheimer’s disease, bind to SARS-CoV-2 S protein:human ACE2 complex, as a bronchodilator to improve lung function in various respiratory diseases, and an antioxidant in lipid-like environments. It can also be used as a racemic salt-acidic compound to produce elevated and sustained ketosis.

Uses

Demethyl-Coclaurine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.

Definition

ChEBI: (RS)-norcoclaurine is a norcoclaurine. It is a conjugate base of a (RS)-norcoclaurinium.

Demethyl-Coclaurine Preparation Products And Raw materials

Raw materials

Preparation Products

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Demethyl-Coclaurine Suppliers

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View Lastest Price from Demethyl-Coclaurine manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Demethyl-Coclaurine 5843-65-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-23
Career Henan Chemical Co
Product
Demethyl-Coclaurine 5843-65-2
Price
US $1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
100KG
Release date
2018-12-24

5843-65-2, Demethyl-CoclaurineRelated Search:

MAGNOFLORINE IODIDE, (+)-(RG) (+)-B-HYDRASTINE HCL (+/-)-TETRAHYDROPAPAVEROLINE HYDROBROMIDE DL-LAUDANOSOLINE HYDROBROMIDE TRIHYDRATE D-TUBOCURARINE CHLORIDE (+)-BULBOCAPNINE Tetrahydropapaveroline (-)-BICUCULLINE METHOBROMIDE Tetrahydropapaverine hydrochloride Narcotine DL-LAUDANOSINE BERBAMINE (+)-Bicuculline DL-6'-BROMOLAUDANOSIN BULBOCAPNINE HYDROCHLORIDE (-)-BICUCULLINE METHCHLORIDE, 1(S),9(R) TETRAHYDROBERBERINE AKOS 236-50

  • Demethyl-Coclaurine
  • Higenamine - natural
  • DL-Demethylcoclaurine
  • Norcoclaurine
  • 1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
  • 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
  • 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol
  • 1-(4-Hydroxybenzyl)
  • (RS)-norcoclaurine
  • Higenamine, 98%, from Lindera aggregata (Sims) Kosterm.
  • HigenaMine HydrobroMide Salt
  • 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-
  • Demethyl-Coclaurine USP/EP/BP
  • 5843-65-2
  • Anilines, Aromatic Amines and Nitro Compounds