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Pramlintide

Description Background
Product Name
Pramlintide
CAS No.
151126-32-8
Chemical Name
Pramlintide
Synonyms
CL062;Pramlintide;Triproamylin;Pramlintide D10;Pramlintide Triproamylin;Lys-c[Cys-Asn-Thr-Ala-Thr-Cys]-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu -Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly -Ser-Asn-Thr-Tyr-NH2;PramlintideQ: What is Pramlintide Q: What is the CAS Number of Pramlintide Q: What is the storage condition of Pramlintide Q: What are the applications of Pramlintide
CBNumber
CB31179559
Molecular Formula
C171H267N51O53S2.C2H4O2.H2O
Formula Weight
4027.49
MOL File
151126-32-8.mol
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Pramlintide Property

solubility 
soluble in Water
form 
Solid
color 
White
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge:Cys2-Cys7)
InChIKey
FVNLNEGMCMHEBF-CLRARMPYNA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Medical Isotopes, Inc.
Product number
18747
Product name
PramlintideAcetate
Packaging
25mg
Price
$1500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007088
Product name
PRAMLINTIDE
Purity
95.00%
Packaging
10MG
Price
$2000
Updated
2021/12/16
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Pramlintide Chemical Properties,Usage,Production

Uses

Antidiabetic.

Enzyme inhibitor

This 37-residue pancreatic β-cell hormone (MW = 3.9 kDa; Sequence: KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY), also called Islet Amyloid Polypeptide (IAPP), is co-secreted with insulin and plays a role in glycemic regulation by retarding gastric emptying and promoting satiety. Amylin helps to prevent post-prandial spikes in blood glucose. Amylin potently inhibits (EC50 = 18 pM) amino acid-stimulated glucagon secretion. (Note: Human amylin is amyloidogenic, whereas the synthetic hormone known as Pramlintide (MW = 3951.41g; CAS 151126-32-8; Sequence: KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY-NH2; Tradename: Symlin?) contains three prolyl residues that are found in Rat Amylin (Sequence: KCNTATCATQRLANFLVRSSNNLGPVLPPTNG SNTY) and is nonamyloidogenic.)

storage

Store at -20°C

Description

Pramlintide Synthetic is a single, non-glycosylated polypeptide chain containing 37 amino acids, having a molecular mass of 3949.4 Dalton and a Molecular formula of C171H267N51O53S2.

Background

Pramlintide acetate is a hormone that is released into the bloodstream, in a similar pattern as insulin. Pramlintide aids in the absorption of glucose by slowing gastric emptying, promoting satiety, and inhibiting inappropriate secretion of glucagon, a catabolic hormone that opposes the effects of insulin.

Pramlintide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Pramlintide manufacturers

Chongqing Soarwin Technology Co., Ltd
Product
Pramlintide 151126-32-8
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99.99%
Supply Ability
10 Boxes
Release date
2025-06-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Pramlintide 151126-32-8
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2023-01-12
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Pramlintide 151126-32-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-16

151126-32-8, PramlintideRelated Search:


  • Triproamylin
  • Lys-c[Cys-Asn-Thr-Ala-Thr-Cys]-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu -Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly -Ser-Asn-Thr-Tyr-NH2
  • CL062
  • Pramlintide D10
  • PramlintideQ: What is Pramlintide Q: What is the CAS Number of Pramlintide Q: What is the storage condition of Pramlintide Q: What are the applications of Pramlintide
  • Pramlintide
  • Pramlintide Triproamylin
  • 151126-32-8