Cetrorelix acetate
- Product Name
- Cetrorelix acetate
- CAS No.
- 120287-85-6
- Chemical Name
- Cetrorelix acetate
- Synonyms
- CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
- CBNumber
- CB0316370
- Molecular Formula
- C70H92ClN17O14
- Formula Weight
- 1431.04
- MOL File
- 120287-85-6.mol
Cetrorelix acetate Property
- Melting point:
- >259°C (dec.)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly, Heated), Methanol (Very Slightly)
- form
- Solid
- pka
- 9.82±0.15(Predicted)
- color
- White to Off-White
- InChIKey
- SBNPWPIBESPSIF-MHWMIDJBSA-N
Safety
- Hazardous Substances Data
- 120287-85-6(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- 3536
- Product name
- Cetrorelix acetate
- Packaging
- 1
- Price
- $224
- Updated
- 2021/12/16
- Product number
- 163043
- Product name
- Cetrorelix Acetate
- Packaging
- 5mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- 254921
- Product name
- Cetrorelix Acetate
- Packaging
- 1mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- orb364499
- Product name
- Cetrorelix Acetate
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $695.3
- Updated
- 2021/12/16
- Product number
- orb364499
- Product name
- Cetrorelix Acetate
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $1480.7
- Updated
- 2021/12/16
Cetrorelix acetate Chemical Properties,Usage,Production
Description
Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.
Originator
Asta Medica (Germany)
Uses
Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.
Definition
ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.
brand name
Cetrotide (Serono).
Cetrorelix acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Cetrorelix acetate Suppliers
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View Lastest Price from Cetrorelix acetate manufacturers
- Product
- Cetrorelix acetate 120287-85-6
- Price
- US $23.00-19.00/box
- Min. Order
- 1box
- Purity
- 99%
- Supply Ability
- 100000box
- Release date
- 2024-04-18
- Product
- Cetrorelix acetate 120287-85-6
- Price
- US $0.00-0.00/Box
- Min. Order
- 1Box
- Purity
- 99
- Supply Ability
- 50000KG/month
- Release date
- 2024-04-12
- Product
- Cetrorelix 120287-85-6
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-11-15