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Cetrorelix acetate

Product Name
Cetrorelix acetate
CAS No.
120287-85-6
Chemical Name
Cetrorelix acetate
Synonyms
CETRORELIX;Cetrorelixum;Unii-oon1hfz4ba;CETRORELIX ACID;Cetrorelix acetate;Cetrorelixum [inn-latin];CETRIZINEDIHYDROCHLORIDE;Cetrorelix?Acetate impurity;Cetrorelix acetate USP/EP/BP;Cetrorelix(Cetrorelix acetate)
CBNumber
CB0316370
Molecular Formula
C70H92ClN17O14
Formula Weight
1431.04
MOL File
120287-85-6.mol
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Cetrorelix acetate Property

Melting point:
>259°C (dec.)
Density 
1.42±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly, Heated), Methanol (Very Slightly)
form 
Solid
pka
9.82±0.15(Predicted)
color 
White to Off-White
InChIKey
SBNPWPIBESPSIF-MHWMIDJBSA-N
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Safety

Hazardous Substances Data
120287-85-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Tocris
Product number
3536
Product name
Cetrorelix acetate
Packaging
1
Price
$224
Updated
2021/12/16
Usbiological
Product number
163043
Product name
Cetrorelix Acetate
Packaging
5mg
Price
$375
Updated
2021/12/16
Usbiological
Product number
254921
Product name
Cetrorelix Acetate
Packaging
1mg
Price
$480
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
1mg
Price
$695.3
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364499
Product name
Cetrorelix Acetate
Purity
> 95%
Packaging
5mg
Price
$1480.7
Updated
2021/12/16
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Cetrorelix acetate Chemical Properties,Usage,Production

Description

Cetrorelix was launched in Germany for the treatment of female infertility. It is a decapeptidic analog of luteinizing hormone-releasing hormone (LH-RH) bearing structural modifications in the crucial positions 1, 2, 3, 6 and 10 : [Ac-D-Nal1, D-4-CI Phe-2, D-Pal3, D-Cit6, D-Alal0]-GnRH. Cetrorelix is an extremely potent and long acting gonadotrophin releasing hormone (GnRH) antagonist and thus blocks gonadotrophins and sex steroid secretion immediately after administration. Moreover, it has a low histamine-releasing potency. Cetrorelix will be the first LH-RH antagonist approved worldwide. In several Phase III clinical trials, female patients receiving Cetrorelix had a successful controlled ovulation thus avoiding a premature LH-surge. Cetrorelix could be a first-choice in-vitro fertilization (IVF) treatment without the complications of current controlled ovarian hyperstimulation protocols. Cetrorelix is currently under clinical investigation for the treatment of diverse sex hormone dependent disorders such as benign prostate hypertrophy, breast, ovarian or prostate cancers and diverse gynaecological disorders.

Originator

Asta Medica (Germany)

Uses

Cetrorelix Acetate is an gonadotropin-releasing hormone antagonist and is used to treat hormone-sensitive cancers of the prostate and breast.

Definition

ChEBI: A synthetic ten-membered oligopeptide comprising N-acetyl-3-(naphthalen-2-yl)-D-alanyl, 4-chloro-D-phenylalanyl, 3-(pyridin-3-yl)-D-alanyl, L-seryl, L-t rosyl, N5-carbamoyl-D-ornithyl, L-leucyl, L-arginyl, L-prolyl, and D-alaninamide residues coupled in sequence. A gonadotrophin-releasing hormone (GnRH antagonist, it is used for treatment of infertility and of hormone-sensitive cancers of the prostate and breast.

brand name

Cetrotide (Serono).

Cetrorelix acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Cetrorelix acetate Suppliers

Hangzhou nuotong biotechnology co. LTD
Tel
0571-86297909 15268405618
Email
sisi.xiang@sinopep.com
Country
China
ProdList
87
Advantage
58
Chinapeptide
Tel
15295566865 15295566865
Email
glenn@synpeptide.com
Country
China
ProdList
31
Advantage
58
Chinese Peptide Company
Tel
0571-86737118-8680 15988144796
Email
sales@chinesepeptide.com
Country
China
ProdList
12
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
967
Advantage
59
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Cetrorelix acetate manufacturers

Shanghai Affida new material science and technology center
Product
Cetrorelix acetate 120287-85-6
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99
Supply Ability
50000KG/month
Release date
2024-04-12
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cetrorelix acetate 120287-85-6
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2021-10-28
Hebei Fengjia New Material Co., Ltd
Product
Cetrorelix acetate 120287-85-6
Price
US $6.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2024-09-10

120287-85-6, Cetrorelix acetateRelated Search:


  • AC-(D-ALA[3-(2-NAPHTHYL)])-[D-PHE(4-CL)]-(D-ALA[3-(3-PYRIDYL)])-SER-TYR-(D-CIT)-LEU-ARG-PRO-D-ALA-OH
  • Cetrorelix acetate
  • CETRORELIX
  • CETRORELIX ACID
  • CETRIZINEDIHYDROCHLORIDE
  • N-Acetyl-3-(2-naphthalenyl)-D-Ala-4-chloro-D-Phe-3-(3-pyridyl)-D-Ala-L-Ser-L-Tyr-N5-(aminocarbonyl)-D-Orn-L-Leu-L-Arg-L-Pro-D-Ala-NH2
  • Cetrorelixum
  • Cetrorelixum [inn-latin]
  • Unii-oon1hfz4ba
  • Ac-D-2-Nal-4-chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2 acetate salt
  • D-AlaninaMide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aMinocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-
  • Ac-D-2-Nal-4-chloro-D-Phe-b-(3-pyridyl)-D-Ala-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2
  • Cetrorelix?Acetate impurity
  • Cetrorelix acetate USP/EP/BP
  • Cetrorelix(Cetrorelix acetate)
  • Ac-D2Nal-D4Cpa-D3Pal-DSer-Tyr-DCit-Leu-Arg-Pro-DAla-NH2
  • 120287-85-6
  • 20287-85-6
  • C70H92ClN17O14
  • C70H92CIN17O14C2H4O2
  • Peptide
  • GYL