Tenidap
- Product Name
- Tenidap
- CAS No.
- 120210-48-2
- Chemical Name
- Tenidap
- Synonyms
- TENIDAP;AKOS 91367;TENIDAP USP/EP/BP;CP66248,CP-66248-2;5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
- CBNumber
- CB3121977
- Molecular Formula
- C14H9ClN2O3S
- Formula Weight
- 320.75
- MOL File
- 120210-48-2.mol
Tenidap Property
- Melting point:
- 230° (dec)
- Boiling point:
- 538.1±60.0 °C(Predicted)
- Density
- 1.648±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- DMSO: soluble1mg/mL, clear (warmed)
- form
- powder
- pka
- 4.50±1.00(Predicted)
- color
- faint yellow to dark yellow
N-Bromosuccinimide Price
- Product number
- PZ0196
- Product name
- Tenidap
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $129
- Updated
- 2024/03/01
- Product number
- PZ0196
- Product name
- Tenidap
- Purity
- ≥97% (HPLC)
- Packaging
- 25mg
- Price
- $401
- Updated
- 2024/03/01
- Product number
- 17413
- Product name
- Tenidap
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17413
- Product name
- Tenidap
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 17413
- Product name
- Tenidap
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $122
- Updated
- 2024/03/01
Tenidap Chemical Properties,Usage,Production
Uses
Anti-inflammatory (osteoarthritis and rheumatoid arthritis).
Uses
Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.
Definition
ChEBI: Tenidap is a member of indoles, a member of ureas, a member of thiophenes and an organochlorine compound. It has a role as a non-steroidal anti-inflammatory drug and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor.
Biological Activity
NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM).
storage
Store at +4°C
Mode of action
Tenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1).
Tenidap Preparation Products And Raw materials
Raw materials
Preparation Products
Tenidap Suppliers
View Lastest Price from Tenidap manufacturers
- Product
- TENIDAP 120210-48-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-06