ChemicalBook > CAS DataBase List > 2-Ethyl-2-phenylmalonamide

2-Ethyl-2-phenylmalonamide

Product Name
2-Ethyl-2-phenylmalonamide
CAS No.
7206-76-0
Chemical Name
2-Ethyl-2-phenylmalonamide
Synonyms
PEMA;pema(amide);Primidone Impurity A;Phenylethylmalonamide;Primidone, M(diamide);Ethylphenylmalonamide;Ethylphenylmalondiamide;Primidone EP Impurity A;Phenylethylmalondiamide;Phenobarbital Impurity 5
CBNumber
CB3122121
Molecular Formula
C11H14N2O2
Formula Weight
206.24
MOL File
7206-76-0.mol
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2-Ethyl-2-phenylmalonamide Property

Melting point:
120°C
Boiling point:
440.9±45.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
Flash point:
113 °C
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
14.98±0.50(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
<0.01 g/100 mL at 18 ºC
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
NIST Chemistry Reference
Propanediamide, 2-ethyl-2-phenyl-(7206-76-0)
EPA Substance Registry System
2-Phenyl-2-ethylmalonamide (7206-76-0)
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Safety

HS Code 
2924296000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3110
Product name
Primidone Related Compound A
Purity
pharmaceutical secondary standard, certified reference material
Packaging
50MG
Price
$652.65
Updated
2025/07/31
Sigma-Aldrich
Product number
1562011
Product name
Primidone Related Compound A
Packaging
20mg
Price
$1260
Updated
2025/07/31
TRC
Product number
E925455
Product name
2-Ethyl-2-phenylmalonamide
Packaging
100mg
Price
$205
Updated
2021/12/16
Usbiological
Product number
011760
Product name
2-Ethyl-2-phenylmalonamide
Packaging
25mg
Price
$425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0008724
Product name
2-ETHYL-2-PHENYLMALONAMIDE
Purity
95.00%
Packaging
25MG
Price
$721.88
Updated
2021/12/16
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2-Ethyl-2-phenylmalonamide Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

A metabolite of Primidone

Definition

ChEBI: Phenylethylmalonamide is an amine.

General Description

White crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2-Ethyl-2-phenylmalonamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

SYMPTOMS: Symptoms of exposure to a related compound through ingestion may include sedation, vertigo, dizziness, nausea, vomiting, ataxia, diplopia, nystagmus, an acute feeling of intoxication and, rarely, maculopapular and morbilliform rash, leukopenia, thrombocytopenia, systemic lupus erythematosus, lymphadenopathy, acute psychotic reactions, hemorrhagic disease in the neonate, megaloblastic anemia and osteomalacia.

Fire Hazard

Flash point data for 2-Ethyl-2-phenylmalonamide are not available. 2-Ethyl-2-phenylmalonamide is probably combustible.

2-Ethyl-2-phenylmalonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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7206-76-0, 2-Ethyl-2-phenylmalonamideRelated Search:


  • ETHYLPHENYLMALONIC ACID DIAMINE
  • 2-ETHYL-2-PHENYLMALONAMIDE
  • PEMA
  • 2-ethyl-2-phenyl-malonamid
  • 2-Ethyl-2-phenylmalondiamide
  • 2-Ethyl-2-phenylmalonic diamide
  • 2-ethyl-2-phenyl-propanediamid
  • 2-ethyl-2-phenylpropanediamide
  • Ethylphenylmalondiamide
  • Malonamide, 2-ethyl-2-phenyl-
  • Phenobarbital Impurity 5
  • Primidone Impurity 1(Primidone EP Impurity A)
  • Primidone EP Impurity A
  • pema(amide)
  • Phenylethylmalonamide
  • Phenylethylmalondiamide
  • Primidone, M(diamide)
  • Propanediamide, 2-ethyl-2-phenyl-
  • PriMidone Related CoMpound A
  • Phenobarbital Impurity 1
  • Ethylphenylmalonamide
  • Primidone Related Compound A (2-ethyl-2-phenylmalonamide) (1562011)
  • 2-ethyl-2-phenylpropanediamide(ethylphenylmalonamide)
  • Primidone Impurity A
  • Phenylethylmalonamide (PEMA) solution
  • 7206-76-0
  • Chemical Amines
  • Amines
  • Aromatics
  • Metabolites & Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals