ChemicalBook > CAS DataBase List > Malonamide

Malonamide

Product Name
Malonamide
CAS No.
108-13-4
Chemical Name
Malonamide
Synonyms
PROPANEDIAMIDE;MALONDIAMIDE;NSC 2134;MALONAMIDE;MALONODIAMIDE;Malonamide>AURORA KA-4099;malonicdiamide;Malonyldiamide;Malonamide 98%
CBNumber
CB2418973
Molecular Formula
C3H6N2O2
Formula Weight
102.09
MOL File
108-13-4.mol
More
Less

Malonamide Property

Melting point:
172-175 °C (lit.)
Boiling point:
191.38°C (rough estimate)
Density 
1.3516 (rough estimate)
refractive index 
1.5110 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in HCl.
pka
7.00±0.70(Predicted)
form 
powder to crystal
color 
White to Almost white
Water Solubility 
180 g/L (20 ºC)
BRN 
1751401
InChI
InChI=1S/C3H6N2O2/c4-2(6)1-3(5)7/h1H2,(H2,4,6)(H2,5,7)
InChIKey
WRIRWRKPLXCTFD-UHFFFAOYSA-N
SMILES
C(N)(=O)CC(N)=O
CAS DataBase Reference
108-13-4(CAS DataBase Reference)
NIST Chemistry Reference
Propanediamide(108-13-4)
EPA Substance Registry System
Propanediamide (108-13-4)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
2
RTECS 
ON9125000
TSCA 
Yes
HS Code 
29241900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129593
Product name
Malonamide
Purity
97%
Packaging
100g
Price
$56.58
Updated
2024/03/01
TCI Chemical
Product number
M0027
Product name
Malonamide
Purity
>98.0%(N)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
M0027
Product name
Malonamide
Purity
>98.0%(N)
Packaging
500g
Price
$199
Updated
2024/03/01
Alfa Aesar
Product number
A17939
Product name
Malonamide, 98%
Packaging
100g
Price
$65.65
Updated
2024/03/01
Alfa Aesar
Product number
A17939
Product name
Malonamide, 98%
Packaging
500g
Price
$204.65
Updated
2024/03/01
More
Less

Malonamide Chemical Properties,Usage,Production

Description

Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.

Chemical Properties

White crystalline powder

Uses

Malonamide is a reagent for fluorimetric determination of reducing carbohydrates. The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare earth elements from nitric acid medium.

Uses

The malonamide-based ionic liquid extractant was used in the extraction of europium(iii) and other trivalent rare-earth ions from nitric acid medium.

Uses

Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.

Definition

ChEBI: Malonamide is a dicarboxylic acid diamide that is malonic acid in which both carboxy groups have been replaced by carbamoyl groups. It is functionally related to a malonic acid.

General Description

The malonamide derivatives are obtained by the one-pot, five-component condensation reaction of isocyanide, Meldrum′s acid, arylidene malononitrile, and two amine molecules in CH2Cl2.

Hazard

Mildly toxic by ingestion.

Synthesis

The synthesis of Malonamide is as follows:
A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), CuII-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.

Purification Methods

Crystallise the amide from water. [Beilstein 2 IV 1887.]

Malonamide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Malonamide Suppliers

Nanjing Pope Bio-tech R&D Co., Ltd
Tel
025-87138562
Email
sales@popebiotech.com
Country
China
ProdList
422
Advantage
58
Nanjing Shengkai Pharmaceutical Technology Co., Ltd.
Tel
025-86182925 17749516701
Email
195645838@qq.com
Country
China
ProdList
154
Advantage
58
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1687
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Dr. J. Pharmachem (India)
Tel
+91 20 24332987
Fax
+91 20 24332137
Email
info@jpharmachem.com
Country
India
ProdList
97
Advantage
55
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
More
Less

View Lastest Price from Malonamide manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Malonamide 108-13-4
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-11
Hebei Chuanghai Biotechnology Co,.LTD
Product
Malonamide 108-13-4
Price
US $9.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
100tons
Release date
2024-08-23
Hebei Mojin Biotechnology Co., Ltd
Product
Malonamide 108-13-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-25

108-13-4, MalonamideRelated Search:


  • MALONODIAMIDE
  • MALONIC ACID DIAMIDE
  • MALONDIAMIDE
  • MALONIC ACID AMIDE
  • MALONAMIDE
  • METHANEDICARBOXYLIC ACID DIAMIDE
  • DICARBOXYMETHANE DIAMIDE
  • LABOTEST-BB LT01598526
  • AURORA KA-4099
  • CARBOXAMIDOACETAMIDE
  • CARBOXYACETIC ACID DIAMIDE
  • PROPANEDIAMIDE
  • PROPANEDIOIC ACID DIAMIDE
  • malonicdiamide
  • Malonyldiamide
  • MALONAMIDE, FOR FLUORESCENCE
  • MALONAMIDE 99+%
  • Malonamide 98%
  • Propane-1,3-diamide
  • MALONAMIDE extrapure
  • 3-Amino-3-oxopropanamide
  • Malonamide,97%
  • NSC 2134
  • Propylene aMide
  • MALONAMIDE FOR SYNTHESIS 100 G
  • MalonaMide , 98.0%(N)
  • Malonamide&gt
  • Malonamide ISO 9001:2015 REACH
  • 108-13-4
  • CH2CONH22
  • C3H6NO2
  • Organic Building Blocks
  • Fluorescent Probes, Labels, Particles and Stains
  • Detection
  • Building Blocks
  • Biochemicals and Reagents
  • BioChemical
  • Amides
  • Carbonyl Compounds
  • Aliphatics
  • Miscellaneous Reagents
  • Amides
  • Biochemicals and Reagents
  • Building Blocks
  • C2 to C7
  • Carbonyl Compounds
  • Chemical Synthesis
  • Derivatization agents
  • Luminescent Compounds/Detection
  • Organic Building Blocks
  • Wavelength Index
  • API intermediates