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Yangambin

Product Name
Yangambin
CAS No.
13060-14-5
Chemical Name
Yangambin
Synonyms
C10894;YANGAMBIN;(+)-Yangabin;Yangambin, 10 mM in DMSO;Lrioresinol B dimethyl ether;Lirioresinol B dimethyl ether;(+)-O,O-Dimethyl lirioresinol B;yangambin/Lrioresinol B dimethyl ether;inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor;(1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
CBNumber
CB31246402
Molecular Formula
C24H30O8
Formula Weight
446.49
MOL File
13060-14-5.mol
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Yangambin Property

Melting point:
105-106 °C
Boiling point:
556.1±50.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
InChIKey
HRLFUIXSXUASEX-RZTYQLBFSA-N
SMILES
O1C[C@]2([H])[C@@H](C3=CC(OC)=C(OC)C(OC)=C3)OC[C@]2([H])[C@H]1C1=CC(OC)=C(OC)C(OC)=C1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0032586
Product name
Yangambin
Packaging
5mg
Price
$880
Updated
2021/12/16
ChemScene
Product number
CS-0032586
Product name
Yangambin
Packaging
10mg
Price
$1500
Updated
2021/12/16
Arctom
Product number
CFN96416
Product name
Yangambin
Purity
≥98%
Packaging
5mg
Price
$398
Updated
2021/12/16
Crysdot
Product number
CD32002589
Product name
Yangambin
Purity
95+%
Packaging
5mg
Price
$723
Updated
2021/12/16
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Yangambin Chemical Properties,Usage,Production

Uses

Yangambin is one of the active ingredients of Radix Stellerae Chamaejasmes, which is bitter in nature and taste, and is highly toxic. It has the effects of severe diarrhea, prevent decay, and swelling. It is clinically used for erysipelas, mammary carbuncle, swollen mumps (mumps), yellow water sores, and acne.

Definition

ChEBI: Yangambin is a lignan.

Biological Activity

Yangambin is a furofuran lignan that has been isolated from plants such as the Annonaceae family, including: R. pickeli, R. exalbida and R. mucosa and Magnolia biondii. Yangambin is a selective PAF receptor antagonist that inhibits Ca2+ influx by modulating Ca2+ channels, resulting in a decrease in [Ca2+] in vascular smooth muscle cells and subsequent peripheral vasodilation. Yangambin exhibits anti-allergic activity against β-hexosaminidase with IC50 of 33.8 μM and anti-inflammatory activity with IC50 of 37.4 μM.

Yangambin Preparation Products And Raw materials

Raw materials

Preparation Products

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Yangambin Suppliers

Chengdu Caoyuankang Biological Technology Co., Ltd.
Tel
13438898246; 13438898246
Fax
028-67271232
Email
3003796344@qq.com
Country
China
ProdList
599
Advantage
58
Hubei Danding Pharmaceutical Technology Co., Ltd
Tel
17701422019
Email
1559451077@qq.com
Country
China
ProdList
8167
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5645
Advantage
65
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Shanghai Winherb Medical Technology Co., Ltd.
Tel
021-38218169 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1245
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9279
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai Yihe Biological Technology Co., Ltd.
Tel
021-68882955 17721395025
Fax
021-68882955
Email
2423903095@qq.com
Country
China
ProdList
4991
Advantage
58
Shanghai Uteam Biotechnology Co., Ltd.
Tel
021-36031160 13311776681
Email
3338195766@QQ.com
Country
China
ProdList
5093
Advantage
55

13060-14-5, YangambinRelated Search:


  • Lrioresinol B dimethyl ether
  • (1S,3aR,4S,6aR)-Tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
  • (+)-Yangabin
  • C10894
  • YANGAMBIN
  • (+)-O,O-Dimethyl lirioresinol B
  • (1S)-1β,4β-Bis(3,4,5-trimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan
  • (1β,5β)-2β,6β-Bis(3,4,5-trimethoxyphenyl)-3,7-dioxabicyclo[3.3.0]octane
  • [1S,(+)]-3aβ,4,6,6aβ-Tetrahydro-1β,4β-bis(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan
  • Lirioresinol B dimethyl ether
  • 1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,4,5-trimethoxyphenyl)-, (1S,3aR,4S,6aR)-
  • yangambin/Lrioresinol B dimethyl ether
  • (3S,3aR,6S,6aR)-3,6-bis(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
  • inhibit,Calcium Channel,Yangambin,Ca channels,Ca2+ channels,Inhibitor
  • Yangambin, 10 mM in DMSO
  • 13060-14-5
  • 13060-54-5