HEXAMETHONIUM CHLORIDE

Product Name: HEXAMETHONIUM CHLORIDE
CAS No.: 60-25-3
Chemical Name: HEXAMETHONIUM CHLORIDE
Synonyms: depressin;hexonchloride;hiohexchloride;hexonechloride;esomidchloride;methiumchloride;chloor-hexaviet;bistriumchloride;hestriumchloride;hexametonchloride
CBNumber: CB3125713
Molecular Formula: C12H30Cl2N2
Formula Weight: 273.29
MOL File: 60-25-3.mol

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HEXAMETHONIUM CHLORIDE Property

Melting point:: 292°C(dec.)(lit.)
Boiling point:: 423.36°C (rough estimate)
Density: 1.0558 (rough estimate)
refractive index: 1.6400 (estimate)
solubility: H₂O: soluble
form: solid (hygroscopic)
color: white
Water Solubility: almost transparency
BRN: 3714806
CAS DataBase Reference: 60-25-3
EPA Substance Registry System: 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dichloride (60-25-3)

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Safety

WGK Germany: 3
RTECS: BQ8650000
HS Code: 2923.90.0100

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H2138
Product name: Hexamethonium chloride
Purity: solid (hygroscopic)
Packaging: 5g
Price: $33.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: H2138
Product name: Hexamethonium chloride
Purity: solid (hygroscopic)
Packaging: 25g
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: H0090
Product name: Hexamethonium Chloride Dihydrate
Purity: >99.0%(T)
Packaging: 25g
Price: $99
Updated: 2023/01/07

TCI Chemical

Product number: H0090
Product name: Hexamethonium Chloride Dihydrate
Purity: >99.0%(T)
Packaging: 100g
Price: $249
Updated: 2023/01/07

TCI Chemical

Product number: H0090
Product name: Hexamethonium Chloride Dihydrate
Purity: >99.0%(T)
Packaging: 500g
Price: $754
Updated: 2023/01/07

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HEXAMETHONIUM CHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White, crystalline, hygroscopic powder; faint odor. Very soluble in water; soluble in alcohol, methanol, and n-propanol; insoluble in chloroform and ether. Available commercially as unhydrated form or as dihydrate.

Uses

Hexamethonium Chloride is a ganglionic nicotinic receptor blocker.

Uses

Hexamethonium chloride has been used to block the responses of nicotinic receptors towards it agonists. It has also been used to study the mechanosensitivity of viscerofugal neurons.

Uses

Medicine (antihypertensive).

General Description

Nicotinic acetylcholine receptor (nAChR) forms a ligand-gated ion channel made up of four different subunits. Each subunit contains an extracellular amino-terminal domain (hydrophilic) and carboxylic terminal domain and four transmembrane domains. nAChR is an allosteric and transmembrane protein localized to the neuromuscular junction.

Biochem/physiol Actions

Hexamethonium chloride preferentially blocks nicotinic receptors at autonomic ganglia, crosses blood-brain barrier only at high doses. Nicotinic acetylcholine receptor (nAChR) is responsible for cognitive functions. Blocking this receptor results in cognitive impairment. nAChR antagonist is used to study the effect of loss of receptor function. Hexamethonium has a peripheral action over blocking the nAChR.

HEXAMETHONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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HEXAMETHONIUM CHLORIDE Suppliers

Americas 1 China 60 Europe 1 France 1 Germany 3 India 6 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 3 United States 25 Global 104

TargetMol Chemicals Inc.

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View Lastest Price from HEXAMETHONIUM CHLORIDE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Hexamethonium chloride 60-25-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-17

Henan Aochuang Chemical Co.,Ltd.

Product: HEXAMETHONIUM CHLORIDE 60-25-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-10

60-25-3, HEXAMETHONIUM CHLORIDERelated Search:

Dodecyltrimethylammonium Bromide Hexane Ammonium chloride HEXAMETHONIUM CHLORIDE DIHYDRATE triclobisonium chloride dodeconium Poly(diallyldimethylammonium chloride) HEXAMETHONIUM CHLORIDE

6-hexanediaminium,n,n,n,n’,n’,n’-hexamethyl-dichloride

hexonchloride

hexonechloride

hiohexchloride

methiumchloride

A,W-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE

HEXAMETHYLENEBIS[TRIMETHYLAMMONIUM CHLORIDE]

HEXAMETHONIUM CHLORIDE

HEXAMETHONIUM DICHLORIDE

HEXANE-1,6-BIS[TRIMETHYLAMMONIUM CHLORIDE]

ALPHA OMEGA-BIS(TRIMETHYLAMMONIUM)HEXANE DICHLORIDE

n,n,n,n',n',n'-hexamethyl-1,6-hexanediammonium dichloride

bistriumchloride

chloor-hexaviet

depressin

esomidchloride

hestriumchloride

hexamethioniumchloride

hexamethylenebis(trimethyl-ammoniudichloride

hexametonchloride

Hexamethonium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethyl-1,6-hexanediaminium dichloride, N,N,N,Nμ,Nμ,Nμ-Hexamethylhexamethylenediammonium dichloride

Hexamethylenebis(trimethylaminium)·dichloride

N,N,N,N',N',N'-Hexamethyl-1,6-hexanediaminium dichloride

N,N,N,N',N',N'-Hexamethylhexamethylenediammonium dichloride

Hexamethylenebis(trimethylammonium Chloride) N,N,N,N',N',N'-Hexamethyl-1,6-hexanediammonium Dichloride Hexane-1,6-bis(trimethylammonium Chloride)

HexaMethoniuM Chloride&nbsp

N1,N1,N1,N6,N6,N6-hexaMethylhexane-1,6-diaMiniuM chloride

1,6-Hexanediaminium, N1,N1,N1,N6,N6,N6-hexamethyl-, chloride (1:2)

HexamethoniumChlorideDihydrate&gt

Trimethyl-[6-(trimethylazaniumyl)hexyl]azanium Dichloride

Hexamethonium Chloride hydrate

60-25-3

CH33NClCH26NClCH33

C12H30Cl2N2

C12H30Cl2N22H2O

Ammonium Chlorides (Quaternary)

Quaternary Ammonium Compounds