ChemicalBook > CAS DataBase List > N-methylisatoic anhydride

N-methylisatoic anhydride

Product Name
N-methylisatoic anhydride
CAS No.
10328-92-4
Chemical Name
N-methylisatoic anhydride
Synonyms
MIA;NSC439;NSC 439;NSC-439;AKOS 226;AI300638;NSC 76087;MIA human;4-dithiin;AI3 00638
CBNumber
CB3126220
Molecular Formula
C9H7NO3
Formula Weight
177.16
MOL File
10328-92-4.mol
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N-methylisatoic anhydride Property

Melting point:
165 °C (dec.)(lit.)
Boiling point:
309.06°C (rough estimate)
Density 
1.3312 (rough estimate)
vapor density 
6.1 (vs air)
refractive index 
1.5200 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in DMSO
form 
Solid
pka
-2.24±0.20(Predicted)
color 
White to yellow
Sensitive 
Moisture Sensitive
CAS DataBase Reference
10328-92-4(CAS DataBase Reference)
EPA Substance Registry System
2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
RTECS 
DM3140000
TSCA 
Yes
HS Code 
2934.99.4400
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
129887
Product name
N-Methylisatoic anhydride
Purity
technical, 90%
Packaging
100g
Price
$89.2
Updated
2024/03/01
TCI Chemical
Product number
M0743
Product name
N-Methylisatoic Anhydride
Packaging
5G
Price
$102
Updated
2024/03/01
TCI Chemical
Product number
M0743
Product name
N-Methylisatoic Anhydride
Purity
>98.0%(GC)
Packaging
25g
Price
$400
Updated
2024/03/01
Alfa Aesar
Product number
B24099
Product name
N-Methylisatoic anhydride, tech. 90%
Packaging
100g
Price
$58.65
Updated
2024/03/01
TRC
Product number
M293158
Product name
1-Methyl-1H-benzo[d][1,3]oxazine-2,4-dione
Packaging
500mg
Price
$55
Updated
2021/12/16
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N-methylisatoic anhydride Chemical Properties,Usage,Production

Chemical Properties

brownish chunks

Uses

N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.

Definition

ChEBI: N-methylisatoic anhydride is a 3,1-benzoxazin-1,4-dione having an N-methyl substituent.

Application

N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline.

N-methylisatoic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-methylisatoic anhydride Suppliers

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View Lastest Price from N-methylisatoic anhydride manufacturers

Shanghai Rlavie Technology Co ltd
Product
N-Methylisatoic anhydride 10328-92-4
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
500kgs/month
Release date
2021-11-14
Career Henan Chemical Co
Product
N-METHYLISATOIC ANHYDRIDE 10328-92-4
Price
US $100.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-07-25
Career Henan Chemical Co
Product
N-METHYLISATOIC ANHYDRIDE 10328-92-4
Price
US $20.00/KG
Min. Order
1KG
Purity
995
Supply Ability
20kg
Release date
2018-07-30

10328-92-4, N-methylisatoic anhydrideRelated Search:

5-Chloro-N-methylisatoic anhydride N-methylisatoic anhydride Ethyl 4-dimethylaminobenzoate Isatoic Anhydride 1-ISOPROPYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE N-BENZYLISATOIC ANHYDRIDE 5-CHLORO-1-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE 3-METHOXY-N-METHYLISATOIC ANHYDRIDE N-ALLYLISATOIC ANHYDRIDE 6-Methylisatoic anhydride 5-METHYLISATOIC ANHYDRIDE 7-FLUORO-2-METHYLISATOIC ANHYDRIDE AMILORIDE, 5-(N-METHYL-N-ISOBUTYL) (MIA) >97% EXTREMELY POTE,MIA 6-CHLORO-N-METHYLISATOIC ANHYDRIDE N-METHYLISATOIC ANHYDRIDE POLYSTYRENE (100-200 MESH, 3 MMOL/G) HUMAN MIA KG POA 5-METHYLISATOIC ANHYDRIDE MIA protein

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  • Isatoic anhydride, N-Methyl-
  • N-Methylisatioc anhydride
  • 1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione
  • 1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione
  • 1-Methyl-1H-3,1-benzoxazine-2,4-dione
  • 1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione
  • N-Methylisatoic anhydride,90%,tech.
  • N-Methylisatoic anhydride (NMIA)
  • 1-methyl-3,1-benzoxazine-2,4-dione
  • <i>N</i>-Methylisatoic Anhydride
  • MIA
  • N-METHYLISATOIC ANHYDRIDE
  • TIMTEC-BB SBB000196
  • 1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione
  • 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl-
  • 4(1h)-dione,1-methyl-2h-1-benzoxazine-2
  • N-Methyl ia
  • n-methylia
  • N-Methyl-N-carboxyanthranilic anhydride
  • N-METHYLISATOIC ANHYDRIDE, TECH., 90%
  • N-Methylisatoicanhydride,tech.,90%
  • AKOS 226
  • 1-Methyl-4H-3,1-benzoxazine-2,4(1H)dione
  • N-Methylisatoic acid anhydride
  • NSC 76087
  • N-Methylisatoic anhydride technical, 90%
  • Melanoma-derived growth regulatory protein precursor
  • MIA human
  • N-MethylisatoicAnhydride&gt
  • 10-Dithiaanthracene
  • 4-dithiin
  • AI3 00638
  • AI300638
  • AI3-00638
  • dibenzo-1
  • NSC 439
  • NSC439
  • NSC-439
  • 10328-92-4
  • 10328-92-7
  • Monomers
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  • pharmacetical
  • Anhydride Monomers