7-Aminoisoquinoline
- Product Name
- 7-Aminoisoquinoline
- CAS No.
- 23707-37-1
- Chemical Name
- 7-Aminoisoquinoline
- Synonyms
- 7-Isoquinolinamine;7-Aminoisoquinoline;7-amine-isoquinoline;Isoquinolin-7-ylamine;7-Isoquinolinamine(9CI);7-aminoisoquinoline ,97%;7-Aminoisoquinoline ISO 9001：2015 REACH
- CBNumber
- CB31287133
- Molecular Formula
- C9H8N2
- Formula Weight
- 144.17
- MOL File
- 23707-37-1.mol
7-Aminoisoquinoline Property
- Melting point:
- 204 °C
- Boiling point:
- 343.1±15.0 °C(Predicted)
- Density
- 1.210±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 6.18±0.10(Predicted)
- color
- Off-white to yellow
Safety
- Safety Statements
- 24/25
- HS Code
- 29334900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I918265
- Product name
- Isoquinolin-7-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 069892
- Product name
- 7-Aminoisoquinoline
- Purity
- 97%
- Packaging
- 1g
- Price
- $94
- Updated
- 2021/12/16
- Product number
- W4739
- Product name
- 7-Aminoisoquinoline
- Packaging
- 1g
- Price
- $176
- Updated
- 2021/12/16
- Product number
- 3H30-1-D8
- Product name
- 7-Aminoisoquinoline
- Packaging
- 500mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 3H30-1-D8
- Product name
- 7-Aminoisoquinoline
- Packaging
- 1g
- Price
- $395
- Updated
- 2021/12/16
7-Aminoisoquinoline Chemical Properties,Usage,Production
Chemical Properties
Tan powder
Uses
7-Aminoisoquinoline is an isoquinoline compound with substitutable amino groups on its benzene ring structure, mainly used as pharmaceutical intermediates. Studies have shown that the novel 7-aminoisoquinoline-5,8-quinone derivatives have anti-tumour effects on cancer cells.
Synthesis
13058-73-6
23707-37-1
Synthesis of 7-aminoisoquinoline: To a suspension of methanol (20 mL) containing Pd/C (10%, 100 mg) was added a solution of 7-nitroisoquinoline (200 mg, 1.15 mmol) in methanol (40 mL). The system was degassed and charged with hydrogen, followed by stirring the reaction mixture at room temperature for 24.5 hours. The completion of the reaction was confirmed by TLC monitoring. The reaction mixture was filtered to remove the Pd/C catalyst and the filtrate was concentrated under reduced pressure to remove the solvent. The resulting residue (150 mg, 90% yield) was used for subsequent reactions without further purification.
References
[1] Patent: US9138427, 2015, B2. Location in patent: Page/Page column 307
[2] Journal of the Chemical Society, 1951, p. 2851
[3] Patent: US5807886, 1998, A
[4] Journal of the American Chemical Society, 2011, vol. 133, # 20, p. 8014 - 8027
[5] Synlett, 2013, vol. 24, # 3, p. 301 - 304
7-Aminoisoquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-Aminoisoquinoline manufacturers
- Product
- 7-Aminoisoquinoline 23707-37-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 7-Aminoisoquinoline 23707-37-1
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02