2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID
- Product Name
- 2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID
- CAS No.
- 259269-84-6
- Chemical Name
- 2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID
- Synonyms
- BUTTPARK 35\07-04;2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID;2-Amino-3-bromo-5-fluorobenzoicacid,95%;Benzoic acid, 2-amino-3-bromo-5-fluoro-;3-Bromo-5-fluoroanthranilic acid, 2-Bromo-6-carboxy-4-fluoroaniline
- CBNumber
- CB3129296
- Molecular Formula
- C7H5BrFNO2
- Formula Weight
- 234.02
- MOL File
- 259269-84-6.mol
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID Property
- Melting point:
- 202-205°
- Boiling point:
- 344.0±42.0 °C(Predicted)
- Density
- 1.877±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 4.21±0.10(Predicted)
- form
- Solid
- Appearance
- Off-white to yellow Solid
- InChI
- InChI=1S/C7H5BrFNO2/c8-5-2-3(9)1-4(6(5)10)7(11)12/h1-2H,10H2,(H,11,12)
- InChIKey
- LTOCPZGBNWZMBA-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(F)=CC(Br)=C1N
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 2922498590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A594855
- Product name
- 2-Amino-3-bromo-5-fluorobenzoicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA105769
- Product name
- 2-amino-3-bromo-5-fluorobenzoic Acid
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 034810
- Product name
- 2-Amino-3-bromo-5-fluorobenzoicacid
- Purity
- 90%
- Packaging
- 10g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA105769
- Product name
- 2-amino-3-bromo-5-fluorobenzoic Acid
- Packaging
- 2g
- Price
- $96
- Updated
- 2021/12/16
- Product number
- PC32490
- Product name
- 2-Amino-3-bromo-5-fluorobenzoicacid
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
446-08-2
259269-84-6
General procedure for the synthesis of 2-amino-3-bromo-5-fluorobenzoic acid from 2-amino-5-fluorobenzoic acid: N-bromosuccinimide (631 mg, 3.55 mmol) was added in batches to a stirred solution of 2-amino-5-fluorobenzoic acid (7,500 mg, 3.22 mmol) dissolved in acetic acid (5 mL) and the reaction mixture was stirred at room temperature overnight . The resulting precipitate was collected by filtration, washed with petroleum ether (20 mL) and dried to constant weight to afford 2-amino-3-bromo-5-fluorobenzoic acid (11,501 mg, 66.4% yield) as a clear beige solid. The product was used without further purification. The product characterization data were as follows: LCMS (t R = 1.35 min, purity = 100%), no ions detected at ESI m/z; 1H NMR (DMSO-d6) δ (ppm) 6.76 (broad single peak, 2H), 7.55 (double peak, J = 3.0 Hz, JH-F = 9.4 Hz, 1H), 7.71 (double peak, J = 3.0 Hz, JH F = 7.8 Hz, 1H), 12.72 (broad single peak, 1H); 13C NMR (DMSO-d6) δ (ppm) 109.4 (double peak, JC-F = 7.1 Hz), 111.1 (double peak, JC-F = 7.1 Hz), 116.2 (double peak, JC-F = 22.1 Hz), 124.9 (double peak, JC-F = 24.8 Hz), 145.1, 151.4 (double peaks, JC-F = 235.3 Hz), 168.1 (double peaks, JC-F = 2.7 Hz).
References
[1] Tetrahedron, 2012, vol. 68, # 2, p. 534 - 543
[2] Patent: EP3287463, 2018, A1. Location in patent: Paragraph 0203; 0208
[3] Patent: US2018/208604, 2018, A1. Location in patent: Paragraph 0502-0503
[4] Patent: WO2016/105564, 2016, A1. Location in patent: Paragraph 0288
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID manufacturers
- Product
- 2-Amino-3-bromo-5-fluorobenzoic acid 259269-84-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-08-20
- Product
- 2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID 259269-84-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-05
- Product
- 2-AMino-3-broMo-5-fluorobenzoicacid 259269-84-6
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-07