3-Bromo-5-fluorobenzoic acid
- Product Name
- 3-Bromo-5-fluorobenzoic acid
- CAS No.
- 176548-70-2
- Chemical Name
- 3-Bromo-5-fluorobenzoic acid
- Synonyms
- 3-Bromo-5-fluorobenzoic;BUTTPARK 24\01-97;3-BROMO-5-FLUOROBENZOIC ACID;3-FLUORO-5-BROMOBENZOIC ACID;5-BROMO-3-FLUOROBENZOIC ACID;5-fluoro-3-bromobenzoic acid;Benzoic acid, 3-bromo-5-fluoro-;3-Bromo-5-fluorobenzoic acid 98%;3-FLUORO-5-BROMOBENZOIC ACID 98%;3-Bromo-5-fluorobenzoic Acid >
- CBNumber
- CB7734241
- Molecular Formula
- C7H4BrFO2
- Formula Weight
- 219.01
- MOL File
- 176548-70-2.mol
3-Bromo-5-fluorobenzoic acid Property
- Melting point:
- 140 °C
- Boiling point:
- 303.3±27.0 °C(Predicted)
- Density
- 1.789±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 3.47±0.10(Predicted)
- color
- White to Almost white
- Water Solubility
- Insoluble in water.
- InChI
- InChI=1S/C7H4BrFO2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H,10,11)
- InChIKey
- KLSLJMGWUPAQGZ-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC(F)=CC(Br)=C1
- CAS DataBase Reference
- 176548-70-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-36-22
- Safety Statements
- 26-36/37/39-36/37
- HazardClass
- IRRITANT
- HS Code
- 29163100
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B3782
- Product name
- 3-Bromo-5-fluorobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $21
- Updated
- 2025/07/31
- Product number
- B3782
- Product name
- 3-Bromo-5-fluorobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $67
- Updated
- 2025/07/31
- Product number
- B691993
- Product name
- 3-Bromo-5-fluorobenzoic Acid
- Packaging
- 2.5g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- HCH0021317
- Product name
- 3-BROMO-5-FLUORO BENZOIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $611
- Updated
- 2021/12/16
- Product number
- FB37837
- Product name
- 3-Bromo-5-fluorobenzoic acid
- Packaging
- 500g
- Price
- $800
- Updated
- 2021/12/16
3-Bromo-5-fluorobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
light yellow powder
Uses
3-Bromo-5-fluorobenzoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.
Synthesis
179898-34-1
176548-70-2
The general procedure for the synthesis of 3-bromo-5-fluorobenzoic acid from 3-bromo-5-fluorobenzonitrile was as follows: 3-bromo-5-fluorobenzonitrile (2.8 g, 13.8 mmol) was mixed with 5 M aqueous sodium hydroxide (28 mL) and heated to reflux for 2 hr. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with concentrated hydrochloric acid to 1. Subsequently, the precipitate precipitated was collected by filtration, the solid was washed with cold water and dried to give 3-bromo-5-fluorobenzoic acid (2.8 g, 94% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CD3OD): δ 6.31 (dt, J = 8.08, 2.02 Hz, 1H), 6.37-6.43 (m, 1H), 6.68 (s, 1H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 22, p. 6974 - 6979,6
3-Bromo-5-fluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-5-fluorobenzoic acid manufacturers
- Product
- 3-Bromo-5-fluorobenzoic acid 176548-70-2
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-22
- Product
- 3-Bromo-5-fluorobenzoic acid 176548-70-2
- Price
- US $0.10/KG
- Min. Order
- 0.1KG
- Purity
- 98%
- Supply Ability
- 200TONS
- Release date
- 2019-12-24
- Product
- 3-Bromo-5-fluorobenzoic acid 176548-70-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24