asebogenin

Product Name: asebogenin
CAS No.: 520-42-3
Chemical Name: asebogenin
Synonyms: asebogenin;4'-O-Methylphloretin;Dihydroisosakuranetin;Asebogenin, 10 mM in DMSO;1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone;1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-
CBNumber: CB31308236
Molecular Formula: C16H16O5
Formula Weight: 288.3
MOL File: 520-42-3.mol

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asebogenin Property

Melting point:: 168℃
Boiling point:: 550.9±50.0 °C(Predicted)
Density: 1.325±0.06 g/cm3(Predicted)
pka: 7.00±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD32001126
Product name: Asebogenin
Purity: 95+%
Packaging: 5mg
Price: $723
Updated: 2021/12/16

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asebogenin Chemical Properties,Usage,Production

Uses

Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2].

Definition

ChEBI: A member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin.

References

[1] 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. DOI:10.1046/j.1365-3156.1999.00456.x
[2] Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. DOI:10.1111/bph.15964

asebogenin Preparation Products And Raw materials

Raw materials

Preparation Products

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520-42-3, asebogeninRelated Search:

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asebogenin

1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone

4'-O-Methylphloretin

1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-

Asebogenin, 10 mM in DMSO

Dihydroisosakuranetin

520-42-3