2-Hydroxy-4-quinolincarboxylic acid

Product Name: 2-Hydroxy-4-quinolincarboxylic acid
CAS No.: 15733-89-8
Chemical Name: 2-Hydroxy-4-quinolincarboxylic acid
Synonyms: AKOS AUF0188;RARECHEM AQ NN 0221;IFLAB-BB F1918-0080;2-hydroxycinchoninic;4-carboxycarbostyril;Cinchocaine impurity B;Piraxostat Impurity 7;2-hydroxy-cinchoninicaci;2-HYDROXYCINCHONINIC ACID;Cinchocaine EP Impurity B
CBNumber: CB3132467
Molecular Formula: C10H7NO3
Formula Weight: 189.17
MOL File: 15733-89-8.mol

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2-Hydroxy-4-quinolincarboxylic acid Property

Melting point:: 350°C
Boiling point:: 403.6±45.0 °C(Predicted)
Density: 1.429±0.06 g/cm3(Predicted)
vapor pressure: 0Pa at 25℃
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Sonicated)
form: Solid
pka: 2.76±0.20(Predicted)
color: Yellow to Dark Yellow
BRN: 148331
InChI: InChI=1S/C10H7NO3/c12-9-5-7(10(13)14)6-3-1-2-4-8(6)11-9/h1-5H,(H,11,12)(H,13,14)
InChIKey: MFSHNFBQNVGXJX-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC=C2)C(C(O)=O)=CC1=O
LogP: 0.3 at 25℃ and pH7
CAS DataBase Reference: 15733-89-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
RTECS: GD3869000
HazardClass: IRRITANT
HS Code: 29337900
Toxicity: mouse,LD,intraperitoneal,> 500mg/kg (500mg/kg),"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 5, Pg. 338, 1953.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS019980
Product name: 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 100 mg
Price: $73.1
Updated: 2025/07/31

TCI Chemical

Product number: H1016
Product name: 2-Hydroxyquinoline-4-carboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $42
Updated: 2025/07/31

TCI Chemical

Product number: H1016
Product name: 2-Hydroxyquinoline-4-carboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $123
Updated: 2025/07/31

TRC

Product number: D450530
Product name: 1,2-Dihydro-2-oxo-4-quinolinecarboxylicAcid
Packaging: 100g
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: OR911510
Product name: 2-Hydroxyquinoline-4-carboxylic acid
Purity: 98%
Packaging: 100g
Price: $135
Updated: 2021/12/16

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2-Hydroxy-4-quinolincarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

1,?2-?Dihydro-?2-?oxo-4-?quinolinecarboxylic Acid is a chemical constituent of vinegar Schisandra chinensis and is used as a indicator reagent in marking security documents.

Definition

ChEBI: 2-oxo-1,2-dihydroquinoline-4-carboxylic acid is a quinolinemonocarboxylic acid. It is a conjugate acid of a 2-oxo-1,2-dihydroquinoline-4-carboxylate.

Synthesis

141-82-2

91-56-5

15733-89-8

1. Add 400kg of recovered glacial acetic acid to the 1000L reactor and start stirring. 2. 100kg of indigo, 160kg of malonic acid and 15kg of sodium acetate were added sequentially to the reactor to ensure adequate mixing. 3. The reaction mixture was heated to reflux and the reflux reaction was maintained for 6 hours. 4. Upon completion of the reaction, the acetic acid was removed by distillation under reduced pressure. 5. 300 kg of deionized water was added to the reaction mixture and stirred to promote crystal formation. 6. 6. The solid product was collected by filtration, washed with 30 kg of cold glacial acetic acid, and then rinsed with 30 kg of cold methanol to obtain the wet product of 2-quinolinone-4-carboxylic acid. 7. The wet product was dried at 45-70 °C for 24 h. 125 kg of 2-quinolinone-4-carboxylic acid was finally obtained with a yield of 97.3% and a liquid phase purity of 99.6%.

References

[1] Patent: CN108101842, 2018, A. Location in patent: Paragraph 0021; 0023
[2] Synthetic Communications, 2005, vol. 35, # 17, p. 2243 - 2250
[3] Patent: WO2013/153357, 2013, A1. Location in patent: Page/Page column 44
[4] Patent: US2015/45354, 2015, A1. Location in patent: Paragraph 0271-0274
[5] Chemische Berichte, 1914, vol. 47, p. 358

2-Hydroxy-4-quinolincarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Hydroxy-4-quinolincarboxylic acid manufacturers

Xiamen Wonderful Bio Technology Co., Ltd.

Product: 2-Hydroxy-4-quinolincarboxylic acid 15733-89-8
Price: US $88.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000T
Release date: 2023-07-24

Baoji Guokang Healthchem co.,ltd

Product: 2-Hydroxy-4-quinolincarboxylic acid 15733-89-8
Price: US $278.00/ASSAYS
Min. Order: 1KG
Purity: 99
Supply Ability: 1000kg
Release date: 2021-06-04

Hebei Zhanyao Biotechnology Co. Ltd

Product: 2-Hydroxy-4-quinolincarboxylic acid 15733-89-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-13

15733-89-8, 2-Hydroxy-4-quinolincarboxylic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate Quinhydrone Folic acid 4,6-Dihydroxypyrimidine 4-Ethyl-5-fluoro-6-hydroxypyrimidine 2-Quinolinol Isoquinoline CHLOROPHOSPHONAZO III Chromium picolinate 8-Hydroxyquinoline Quinclorac Cinchocaine 2-Chloro-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide N-(2-(diethylamino)ethyl)-2-hydroxyquinoline-4-carboxamide Dibucaine IMpurity D Citric acid Ascoric Acid Carboxy styrene-butadiene latex

IFLAB-BB F1918-0080

AKOS AUF0188

1,2-DIHYDRO-2-OXOQUINOLINE-4-CARBOXYLIC ACID

2-HYDROXY-4-QUINOLINCARBOXYLIC ACID

2-HYDROXYCINCHONINIC ACID

RARECHEM AQ NN 0221

1,2-dihydro-2-oxo-4-quinolinecarboxylicaci

2-hydroxy-cinchoninicaci

4-carboxycarbostyril

2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID 98%

2-hydroxycinchoninic

2-Hydroxyquinoline-4-carboxylic acid hydrate, 98+%

2-Hydroxy-4-quinolinecarboxylic acid

2-Oxo-1,2-dihydroquinoline-4-carboxylic acid

##USE H29247## 2-Hydroxyquinoline-4-carboxylic acid hydrate, 98+%

4-quinolinecarboxylic acid, 2-hydroxy-

2-Hydroxyquinoline-4-carboxylic acid, 98+%

2-oxo-1,2-dihydroquinoline-4-carboxylic acid(SALTDATA: 0.7H2O)

2-oxo-1,2-dihydroquinoline-4-carboxylic acid 0.7H2O

2-Hydroxyquinolin-4-carboxylic acid

1,2-Dihydro-2-oxoquinoline-4-carboxylic Acid 2-Hydroxycinchoninic Acid

2-oxo-4-quinolinecarboxylic acid

1,2-Dihydro-2-oxo-quinolin-4-carboxylic acid

Methyl 2-hydroxyquinoline-4-carboxylate

1,2-Dihydro-2-oxo-4-quinolinecarboxylic acid

4-Quinolinecarboxylicacid, 1,2-dihydro-2-oxo-

Cinchocaine EP Impurity B

1,2-Dihydro-2-oxo-4-Cinchocaine EP Impurity B

Cinchocaine impurity B

2-Hydroxyquinoline-4-carboxylicAcid&gt

Cinchocaine EP Impurity B (2-Hydroxyquinoline-4-Carboxylic Acid)

1,2-Dihydro-2-Oxoquinoline-4-CarboxylicAci

2-Hydroxy-4-quinolincarboxylic acid ISO 9001：2015 REACH

Cinchocaine Hydrochloride Impurity B

Cinchocaine Hydrochloride EP Impurity B

Piraxostat Impurity 7

Cinchocaine impurity B【Y0002032】

Cinchocaine Hydrochloride Imp. B (EP): 2-Hydroxyquinoline-4-

15733-89-8

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