ChemicalBook > CAS DataBase List > 5,7,4'-trihydroxy-8-methoxyflavone

5,7,4'-trihydroxy-8-methoxyflavone

Product Name: 5,7,4'-trihydroxy-8-methoxyflavone
CAS No.: 57096-02-3
Chemical Name: 5,7,4'-trihydroxy-8-methoxyflavone
Synonyms: -Hydroxywogonin;4'-Hydroxywogonin;5,7,4'-trihydroxy-8-methoxyflavone;5,7-dihydroxy-2-(4-hydroxyphenyl)-8-methoxychromen-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-8-methoxy-
CBNumber: CB31350725
Molecular Formula: C16H12O6
Formula Weight: 300.26
MOL File: 57096-02-3.mol

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5,7,4'-trihydroxy-8-methoxyflavone Property

Melting point:: 303-305 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point:: 578.1±50.0 °C(Predicted)
Density: 1.512±0.06 g/cm3(Predicted)
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: powder
pka: 6.84±0.40(Predicted)
color: Yellow
InChI: InChI=1S/C16H12O6/c1-21-15-12(20)6-10(18)14-11(19)7-13(22-16(14)15)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3
InChIKey: OEZZJTAJYYSQKM-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(O)C=C2)OC2=C(OC)C(O)=CC(O)=C2C(=O)C=1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PXT0002309
Product name: 4'-HYDROXYWOGONIN
Purity: 95.00%
Packaging: 5MG
Price: $502.92
Updated: 2021/12/16

AK Scientific

Product number: W1620
Product name: 4'-Hydroxywogonin
Packaging: 5mg
Price: $522
Updated: 2021/12/16

Crysdot

Product number: CD32000956
Product name: 4'-Hydroxywogonin
Purity: 95+%
Packaging: 5mg
Price: $730
Updated: 2021/12/16

Arctom

Product number: CFN98960
Product name: 4'-Hydroxywogonin
Packaging: 10mg
Price: $268
Updated: 2021/12/16

Arctom

Product number: AS022681
Product name: 4'-Hydroxywogonin
Packaging: 5mg
Price: $282
Updated: 2021/12/16

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5,7,4'-trihydroxy-8-methoxyflavone Chemical Properties,Usage,Production

Uses

4''-Hydroxywogonin can be used as an antiviral drug screening for COVID-19 therapy.

in vivo

4′-Hydroxywogonin (10 and 20 mg/kg; i.p.; male C57BL/6 mice) alleviates LPS-induced acute lung injury (ALI) in a mouse model^[1].

Animal Model:	Male C57BL/6 mice (6-8 weeks old; 20 g) with acute lung injury model^[1]
Dosage:	10 and 20 mg/kg
Administration:	Intraperitoneal injection, 12 and 1 h before LPS treatment
Result:	Had potential protective effects against inflammation in LPS induced ALI mice. Attenuated the degree of leukocyte infiltration.

5,7,4'-trihydroxy-8-methoxyflavone Preparation Products And Raw materials

Raw materials

Preparation Products

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