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Bromisoval

Product Name
Bromisoval
CAS No.
496-67-3
Chemical Name
Bromisoval
Synonyms
BVU;Alural;B.V.U.;Bromyl;Abroval;Alluval;Somnurol;Bromaral;Bromoval;Bromoxil
CBNumber
CB3138005
Molecular Formula
C6H11BrN2O2
Formula Weight
223.07
MOL File
496-67-3.mol
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Bromisoval Property

Melting point:
152 °C
Density 
1.6005 (rough estimate)
refractive index 
1.5410 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.54±0.70(Predicted)
color 
White to Off-White
Water Solubility 
19.03g/L(temperature not stated)
Merck 
14,1397
InChIKey
CMCCHHWTTBEZNM-UHFFFAOYSA-N
CAS DataBase Reference
496-67-3(CAS DataBase Reference)
NIST Chemistry Reference
Bromisovalum(496-67-3)
EPA Substance Registry System
Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl- (496-67-3)
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Safety

RTECS 
YS3150000
HS Code 
2924.19.8000
Toxicity
LD50 in male mice (mmoles/kg): 3.25 i.p. (Mrongovius)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B2842
Product name
1-(2-Bromoisovaleryl)urea
Purity
>98.0%(T)
Packaging
25g
Price
$109
Updated
2024/03/01
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
100g
Price
$240
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
10g
Price
$105
Updated
2021/12/16
Usbiological
Product number
159423
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$319
Updated
2021/12/16
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Bromisoval Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Bromisovalum,Linhai Duqiao Fine Chemical Factory

Uses

2-Bromo-3-methylbutyrylurea is a hypnotic and sedative drug marketed over the counter in Asian under various brand names.

Definition

ChEBI: An N-acylurea that is urea in which one of the hydrogens is replaced by a 2-bromo-3-methybutanoyl group.

Manufacturing Process

A mixture of 2 kg 2-bromoisovalerylbromide and 1 kg dry urea is heated at 70°C. Then to the reaction mixture is added sodium hydrogen carbonate. 2- Bromo-3-methylbutyrylurea is recrystallized from toluene or water, melting point 149°C.

brand name

Bromural (Knoll).

Therapeutic Function

Sedative, Hypnotic

World Health Organization (WHO)

Bromisoval is a monureide sedative of long standing. It remains available in several countries. However, it releases the bromide ion and prolonged usage can result in chronic bromide accumulation and intoxication.

Safety Profile

Moderately toxic by ingestion. Human systemic effects by ingestion: nausea or vomiting, and coma. A sedative and hypnotic agent. When heated to decomposition it emits very toxic fumes of Brand NOx

Purification Methods

Crystallise it from aqueous EtOH or toluene, and dry it in air. [Beilstein 3 H 63, 3 I 29, 3 II 51, 3 III 123, 3 IV 117.]

Bromisoval Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromisoval Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from Bromisoval manufacturers

Hebei Mojin Biotechnology Co., Ltd
Product
Bromisoval 496-67-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

496-67-3, BromisovalRelated Search:


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  • A-(BROMOISOVALERYL)UREA
  • ALPHA(BROMOISOVALERYL)UREA
  • LABOTEST-BB LT00134620
  • BROMOVALERYLUREA
  • BROMOISOVALERYLUREA
  • BROMO-ISO-VALERYLUREA (ALPHA)
  • BROMISOVAL
  • (2-bromo-3-methylbutyryl)-ure
  • (alpha-Bromo-.beta,beta.-dimethylpropanoyl)urea
  • (alpha-Bromoisovaleroyl)urea
  • 2-Bromisovalerylmocovina
  • 2-Bromo-3-Methylbutyrylurea
  • 2-Bromo-3-methylbutyrylurea deaux Base GP
  • 2-Bromo-isovaleryl urea
  • 2-Monobromoisovalerylurea
  • Abroval
  • Alluval
  • alpha-Bromisovalerylurea
  • alpha-bromo-beta-dimethylpropanoylurea
  • alpha-Bromoisovaleric acid ureide
  • alpha-bromoisovalericacidureide
  • Dormigene
  • Fast Bordeaux Base J
  • Isobromyl
  • monobromoisolvalerylurea
  • Monobromoisovalerylurea
  • N-(2-Bromo-3-methylbutanoyl)urea
  • N-(Ainocar-bonyl)-2-bromo-3-methylbutanamide
  • n-(aminocarbonyl)-2-bromo-3-methyl-butanamid
  • N-(Aminocarbonyl)-2-bromo-3-methylbutanamide
  • Somnurol
  • Urea, (2-bromo-3-methylbutyryl)-
  • Bromisova
  • (RS)-2-Bromoisovalerylurea
  • Urea, (2-bromo-3-methylbutyryl)- (6CI, 8CI)
  • α-Bromoisovaleric acid ureide
  • α-Bromoisovaleroylurea
  • α-Bromo-β-dimethylpropanoylurea
  • alpha-bromoisovaleroylurea
  • Alural
  • B.V.U.
  • Bromaral
  • Bromcarbamide
  • Bromisovalerylurea
  • bromisovalum
  • Bromizoval
  • Bromocarbamide
  • Bromoisovalum
  • Bro-moural
  • Bromoval
  • Bromovalerocarbamide
  • Bromovaleroylurea
  • Bromovaluree
  • Bromoxil
  • Bromural
  • Bromuvan