Bromisoval
- Product Name
- Bromisoval
- CAS No.
- 496-67-3
- Chemical Name
- Bromisoval
- Synonyms
- BVU;Alural;B.V.U.;Bromyl;Abroval;Alluval;Somnurol;Bromaral;Bromoval;Bromoxil
- CBNumber
- CB3138005
- Molecular Formula
- C6H11BrN2O2
- Formula Weight
- 223.07
- MOL File
- 496-67-3.mol
Bromisoval Property
- Melting point:
- 152 °C
- Density
- 1.6005 (rough estimate)
- refractive index
- 1.5410 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 10.54±0.70(Predicted)
- color
- White to Off-White
- Water Solubility
- 19.03g/L(temperature not stated)
- Merck
- 14,1397
- InChIKey
- CMCCHHWTTBEZNM-UHFFFAOYSA-N
- CAS DataBase Reference
- 496-67-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Bromisovalum(496-67-3)
- EPA Substance Registry System
- Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl- (496-67-3)
Safety
- RTECS
- YS3150000
- HS Code
- 2924.19.8000
- Toxicity
- LD50 in male mice (mmoles/kg): 3.25 i.p. (Mrongovius)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B2842
- Product name
- 1-(2-Bromoisovaleryl)urea
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $109
- Updated
- 2024/03/01
- Product number
- B685130
- Product name
- 2-Bromo-3-methylbutyrylurea
- Packaging
- 100g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- B685130
- Product name
- 2-Bromo-3-methylbutyrylurea
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B685130
- Product name
- 2-Bromo-3-methylbutyrylurea
- Packaging
- 10g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- 159423
- Product name
- 2-Bromo-3-methylbutyrylurea
- Packaging
- 1g
- Price
- $319
- Updated
- 2021/12/16
Bromisoval Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Bromisovalum,Linhai Duqiao Fine Chemical Factory
Uses
2-Bromo-3-methylbutyrylurea is a hypnotic and sedative drug marketed over the counter in Asian under various brand names.
Definition
ChEBI: An N-acylurea that is urea in which one of the hydrogens is replaced by a 2-bromo-3-methybutanoyl group.
Manufacturing Process
A mixture of 2 kg 2-bromoisovalerylbromide and 1 kg dry urea is heated at 70°C. Then to the reaction mixture is added sodium hydrogen carbonate. 2- Bromo-3-methylbutyrylurea is recrystallized from toluene or water, melting point 149°C.
brand name
Bromural (Knoll).
Therapeutic Function
Sedative, Hypnotic
World Health Organization (WHO)
Bromisoval is a monureide sedative of long standing. It remains available in several countries. However, it releases the bromide ion and prolonged usage can result in chronic bromide accumulation and intoxication.
Safety Profile
Moderately toxic by ingestion. Human systemic effects by ingestion: nausea or vomiting, and coma. A sedative and hypnotic agent. When heated to decomposition it emits very toxic fumes of Brand NOx
Purification Methods
Crystallise it from aqueous EtOH or toluene, and dry it in air. [Beilstein 3 H 63, 3 I 29, 3 II 51, 3 III 123, 3 IV 117.]
Bromisoval Preparation Products And Raw materials
Raw materials
Preparation Products
Bromisoval Suppliers
View Lastest Price from Bromisoval manufacturers
- Product
- Bromisoval 496-67-3
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50
- Release date
- 2023-04-17
- Product
- Bromisoval 496-67-3
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min,JP
- Supply Ability
- 1ton/month
- Release date
- 2021-06-03
- Product
- Bromisoval 496-67-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-06-20