ChemicalBook > CAS DataBase List > Bromisoval

Bromisoval

Product Name
Bromisoval
CAS No.
496-67-3
Chemical Name
Bromisoval
Synonyms
BVU;Alural;B.V.U.;Bromyl;Abroval;Alluval;Somnurol;Bromaral;Bromoval;Bromoxil
CBNumber
CB3138005
Molecular Formula
C6H11BrN2O2
Formula Weight
223.07
MOL File
496-67-3.mol
More
Less

Bromisoval Property

Melting point:
152 °C
Density 
1.6005 (rough estimate)
refractive index 
1.5410 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.54±0.70(Predicted)
color 
White to Off-White
Water Solubility 
19.03g/L(temperature not stated)
Merck 
14,1397
InChIKey
CMCCHHWTTBEZNM-UHFFFAOYSA-N
CAS DataBase Reference
496-67-3(CAS DataBase Reference)
NIST Chemistry Reference
Bromisovalum(496-67-3)
EPA Substance Registry System
Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl- (496-67-3)
More
Less

Safety

RTECS 
YS3150000
HS Code 
2924.19.8000
Toxicity
LD50 in male mice (mmoles/kg): 3.25 i.p. (Mrongovius)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B2842
Product name
1-(2-Bromoisovaleryl)urea
Purity
>98.0%(T)
Packaging
25g
Price
$109
Updated
2024/03/01
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
100g
Price
$240
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
10g
Price
$105
Updated
2021/12/16
Usbiological
Product number
159423
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$319
Updated
2021/12/16
More
Less

Bromisoval Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Bromisovalum,Linhai Duqiao Fine Chemical Factory

Uses

2-Bromo-3-methylbutyrylurea is a hypnotic and sedative drug marketed over the counter in Asian under various brand names.

Definition

ChEBI: An N-acylurea that is urea in which one of the hydrogens is replaced by a 2-bromo-3-methybutanoyl group.

Manufacturing Process

A mixture of 2 kg 2-bromoisovalerylbromide and 1 kg dry urea is heated at 70°C. Then to the reaction mixture is added sodium hydrogen carbonate. 2- Bromo-3-methylbutyrylurea is recrystallized from toluene or water, melting point 149°C.

brand name

Bromural (Knoll).

Therapeutic Function

Sedative, Hypnotic

World Health Organization (WHO)

Bromisoval is a monureide sedative of long standing. It remains available in several countries. However, it releases the bromide ion and prolonged usage can result in chronic bromide accumulation and intoxication.

Safety Profile

Moderately toxic by ingestion. Human systemic effects by ingestion: nausea or vomiting, and coma. A sedative and hypnotic agent. When heated to decomposition it emits very toxic fumes of Brand NOx

Purification Methods

Crystallise it from aqueous EtOH or toluene, and dry it in air. [Beilstein 3 H 63, 3 I 29, 3 II 51, 3 III 123, 3 IV 117.]

Bromisoval Preparation Products And Raw materials

Raw materials

2-Bromo-3-methylbutanoyl bromide Isovaleric acid 3-Methyl-1-butanol Phosphorus

Preparation Products

More
Less

Bromisoval Suppliers

Americas 1 Canada 1 China 145 Europe 2 Germany 3 India 6 Japan 3 Slovakia 1 United Kingdom 6 United States 24 Global 192
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2208
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8835
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
860
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
027-27-81302488 15972195220
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
1672
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18097
Advantage
56
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5788
Advantage
50
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29764
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Wuhan HongxinKang Fine Chemical Co., Ltd.
Tel
027-59362599 18674037007
Fax
027-84802889
Email
zhuoxingwc@163.com
Country
China
ProdList
949
Advantage
58
Jinan Winwind Biological Technology Co., Ltd
Tel
15153166971
Email
win-wind@hotmail.com
Country
China
ProdList
97
Advantage
58
Wuhan Netcom Electronic Commerce Limited
Tel
18064670521
Fax
0757-88210752
Email
2355935187@ycphar.com
Country
China
ProdList
4879
Advantage
58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
Country
China
ProdList
9590
Advantage
58
Beijing Mesochem Technology Co., Ltd.
Tel
010-57862036 18811083386
Email
msales@mesochem.com
Country
China
ProdList
205
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-51831887 15337167856
Fax
027-51837635 QQ1165326703
Email
hubeixinyuanshun@163.com
Country
China
ProdList
10295
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Guangzhou Tomums Life Science Co., Ltd.
Tel
020-31155029 18902330969
Fax
020-31155029
Email
sales@tomums.cn
Country
China
ProdList
4696
Advantage
58
Hebei Mujin Biotechnology Co.,Ltd
Tel
+86 13288715578 +8613288715578
Email
sales@hbmojin.com
Country
China
ProdList
12830
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Guangzhou TongYi biochemistry technology Co.,LTD
Tel
+8613073028829
Email
mack@tongyon.com
Country
China
ProdList
2994
Advantage
58
Wuhan Golt Biotech Co., Ltd.
Tel
+8615389281203
Email
maria@goltbiotech.com
Country
China
ProdList
970
Advantage
58
Hubei Ipure Biology Co., Ltd
Tel
+8613367258412
Fax
18062427325
Email
ada@ipurechemical.com
Country
China
ProdList
10319
Advantage
58
Baoji Guokang Bio-Technology Co., Ltd.
Tel
0917-3909592 13892490616
Fax
09173909592
Email
gksales1@gk-bio.com
Country
China
ProdList
9310
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15352
Advantage
58
Hebei Binshare New Material Co. Ltd
Tel
+8618633865755
Email
china01@hbbinshare.com
Country
CHINA
ProdList
955
Advantage
58
SIMAGCHEM CORP
Tel
+86-13806087780
Email
sale@simagchem.com
Country
China
ProdList
17365
Advantage
58
Chemwill Asia Co.,Ltd.
Tel
86-21-51086038
Fax
86-21-51861608
Email
chemwill_asia@126.com
Country
CHINA
ProdList
23912
Advantage
58
Hebei Jimi Trading Co., Ltd.
Tel
+86 319 5273535
Email
bestoneforyou@sina.com
Country
CHINA
ProdList
287
Advantage
58
Hubei Zhonglong Kangsheng Fine Chemical Co., Ltd.
Tel
027-027-83855385 13407122916
Fax
027-83855385
Email
353799526@qq.com
Country
China
ProdList
2409
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
Xiamen AmoyChem Co., Ltd
Tel
+86-86-5926051114 +8618959220845
Email
sales@amoychem.com
Country
China
ProdList
6383
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39894
Advantage
58
Jinan Xinzheng Pharmaceutical Technology Co., Ltd.
Tel
0531-88798968 18615218958
Email
yin3684895@126.com
Country
China
ProdList
179
Advantage
58
Wuhan Xinru Chemical Co., Ltd.
Tel
15927387915 15337108568
Email
2769903731@qq.com
Country
China
ProdList
3336
Advantage
58
Henan Duobei Chemical Co., Ltd
Tel
0370-2059268 17550075363
Fax
QQ:2712427897
Email
1124977392@qq.com
Country
China
ProdList
2283
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
More
Less

View Lastest Price from Bromisoval manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Bromisoval 496-67-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

496-67-3, BromisovalRelated Search:

Hydantoin Amytal sodium Propionyl bromide Isoamyl nitrite 3-Methyl-1-butanol ISOVALERIC ANHYDRIDE Urea Isovaleric acid 3-Methyl-1-butene 3-Methyl-2-buten-1-ol Bromine Amobarbital Isoamyl nitrate γ-Methylbutyl nitrate 1-Bromo-2-methylpropane 2-BROMO-3-METHYLBUTANE GRANULAR UREA Bromisoval isopentyl-ure

  • RARECHEM AX KI 5046
  • 1-(2-BROMOISOVALERYL)UREA
  • A-(BROMOISOVALERYL)UREA
  • ALPHA(BROMOISOVALERYL)UREA
  • LABOTEST-BB LT00134620
  • BROMOVALERYLUREA
  • BROMOISOVALERYLUREA
  • BROMO-ISO-VALERYLUREA (ALPHA)
  • BROMISOVAL
  • (2-bromo-3-methylbutyryl)-ure
  • (alpha-Bromo-.beta,beta.-dimethylpropanoyl)urea
  • (alpha-Bromoisovaleroyl)urea
  • 2-Bromisovalerylmocovina
  • 2-Bromo-3-Methylbutyrylurea
  • 2-Bromo-3-methylbutyrylurea deaux Base GP
  • 2-Bromo-isovaleryl urea
  • 2-Monobromoisovalerylurea
  • Abroval
  • Alluval
  • alpha-Bromisovalerylurea
  • alpha-bromo-beta-dimethylpropanoylurea
  • alpha-Bromoisovaleric acid ureide
  • alpha-bromoisovalericacidureide
  • Dormigene
  • Fast Bordeaux Base J
  • Isobromyl
  • monobromoisolvalerylurea
  • Monobromoisovalerylurea
  • N-(2-Bromo-3-methylbutanoyl)urea
  • N-(Ainocar-bonyl)-2-bromo-3-methylbutanamide
  • n-(aminocarbonyl)-2-bromo-3-methyl-butanamid
  • N-(Aminocarbonyl)-2-bromo-3-methylbutanamide
  • Somnurol
  • Urea, (2-bromo-3-methylbutyryl)-
  • Bromisova
  • (RS)-2-Bromoisovalerylurea
  • Urea, (2-bromo-3-methylbutyryl)- (6CI, 8CI)
  • α-Bromoisovaleric acid ureide
  • α-Bromoisovaleroylurea
  • α-Bromo-β-dimethylpropanoylurea
  • alpha-bromoisovaleroylurea
  • Alural
  • B.V.U.
  • Bromaral
  • Bromcarbamide
  • Bromisovalerylurea
  • bromisovalum
  • Bromizoval
  • Bromocarbamide
  • Bromoisovalum
  • Bro-moural
  • Bromoval
  • Bromovalerocarbamide
  • Bromovaleroylurea
  • Bromovaluree
  • Bromoxil
  • Bromural
  • Bromuvan