Dimethyl itaconate

Product Name: Dimethyl itaconate
CAS No.: 617-52-7
Chemical Name: Dimethyl itaconate
Synonyms: DIMETHYL 2-METHYLENESUCCINATE;DIMETHYL METHYLENESUCCINATE;Butanedioic acid, methylene-, dimethyl ester;109533-100G;ized with HQ);METHYL ITACONATE;Itaconate (stabiL;DIMETHYL ITACONATE;Dimethyl itaconate,97%;Dimethyl itaconate 97%
CBNumber: CB3147485
Molecular Formula: C7H10O4
Formula Weight: 158.15
MOL File: 617-52-7.mol

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Dimethyl itaconate Property

Melting point:: 37-41 °C (lit.)
Boiling point:: 208 °C (lit.)
Density: 1.124 g/mL at 25 °C (lit.)
vapor pressure: 4.05Pa at 20℃
refractive index: 1.4457 (estimate)
Flash point:: 213 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Crystalline Low Melting Mass or Liquid
Specific Gravity: 1.124
color: White
Water Solubility: slightly soluble
BRN: 386674
InChIKey: ZWWQRMFIZFPUAA-UHFFFAOYSA-N
LogP: 0.86 at 25℃
CAS DataBase Reference: 617-52-7(CAS DataBase Reference)
NIST Chemistry Reference: Butanedioic acid, methylene-, dimethyl ester(617-52-7)
EPA Substance Registry System: Butanedioic acid, 2-methylene-, 1,4-dimethyl ester (617-52-7)

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Safety

Safety Statements: 24/25
WGK Germany: 3
F: 3
HS Code: 29171900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 109533
Product name: Dimethyl itaconate
Purity: 97%
Packaging: 100g
Price: $71.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 109533
Product name: Dimethyl itaconate
Purity: 97%
Packaging: 500g
Price: $170
Updated: 2025/07/31

TCI Chemical

Product number: I0206
Product name: Dimethyl Itaconate (stabilized with HQ)
Purity: >98.0%(GC)
Packaging: 25g
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: I0206
Product name: Dimethyl Itaconate (stabilized with HQ)
Purity: >98.0%(GC)
Packaging: 500g
Price: $129
Updated: 2025/07/31

Sigma-Aldrich

Product number: 592498
Product name: Dimethyl itaconate
Purity: 99%
Packaging: 25g
Price: $137
Updated: 2025/07/31

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Dimethyl itaconate Chemical Properties,Usage,Production

Chemical Properties

white crystalline low melting mass or liquid

Uses

Dimethyl Itaconate is a chemical reagent used in the synthesis of functionalized 2-isoxazolines used in fragment-based drug discovery.

Uses

Dimethyl itaconate may be used in functionalization of isotactic poly(propylene). It was used in crosslinking of polyesters: poly(isosorbide itaconate)and poly(isosorbide itaconate-co-succinate).

Uses

Dimethyl itaconate can be used for the rhodium catalyzed asymmetric hydrogenation of (S)-dimethyl-2-methylsuccinate and (R)-methyl succinic acid dimethyl ester.

General Description

Dimethyl itaconate undergoes enantioselective Rh(I)-catalyzed hydrogenation which can be enhanced by appropriate choice of substituents on aromatic ring of (1,2-diarylphosphinoxy)cyclohexane.

Flammability and Explosibility

Non flammable

Synthesis

67-56-1

97-65-4

617-52-7

1. Itaconic acid, methanol and catalyst were mixed in a certain ratio and transferred to a 100 mL autoclave. 2. The reaction mixture was continuously stirred at 120 °C. 3. Optimization of the reaction conditions was carried out by adjusting the parameters such as the molar ratio of methanol to itaconic acid, the catalyst dosage and the reaction time. 4. Upon completion of the reaction, the catalyst was separated and recovered through a filtration operation.

Purification Methods

Crystallise the ester from MeOH by cooling to -78o. [Beilstein 2 IV 2229.]

References

[1] Journal of Molecular Catalysis A: Chemical, 2013, vol. 368-369, p. 24 - 30
[2] Heterocycles, 1988, vol. 27, # 8, p. 1887 - 1898
[3] Tetrahedron Letters, 2015, vol. 56, # 27, p. 4119 - 4123
[4] Chemistry and physics of lipids, 2002, vol. 120, # 1-2, p. 9 - 20
[5] Russian Chemical Bulletin, 2005, vol. 54, # 2, p. 348 - 353

Dimethyl itaconate Preparation Products And Raw materials

Raw materials

Sodium sulfate Chloroform Methanol Itaconic acid Sulfuric acid

Preparation Products

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Dimethyl itaconate Suppliers

Americas 1 Belgium 1 China 240 Europe 1 Germany 2 India 3 Japan 4 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 20 Global 281

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TCI (Shanghai) Development Co., Ltd.

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View Lastest Price from Dimethyl itaconate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Dimethyl itaconate 617-52-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-01

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Dimethyl itaconate 617-52-7
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-29

Shaanxi Dideu New Materials Co. Ltd

Product: Dimethyl itaconate 617-52-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-02-23

617-52-7, Dimethyl itaconateRelated Search:

Dimethyl carbonate ETHANE Dimethyl adipate Dimethyl malonate Dimethyl fumarate Dimethyl phthalate Dimethyl sulfate Itaconic acid Dacthal N,N-Dimethylformamide Dimethyl ether Dimethyl sulfoxide Dimethyl phosphite Dimethyl sebacate Dimethyl oxalate Dimethyl sulfide DIETHYL ITACONATE DIBUTYL ITACONATE

Methyl 4-methoxy-2-methylene-4-oxobutanoate

1-Propene-2,3-dicarboxylic acid dimethyl ester

2-Methylenebutanedioic acid dimethyl ester

Dimethyl 1-propene-2,3-dicarboxylate

Dimethyl itaconate,97%

Dimethyl 2-methylidenebutane-1,4-dioate, Dimethyl itaconate

DiMethyl itaconate, 97%, stabilized

Dimethyl itaconate 97%

Dimethyl itaconate,contains ~300ppm HQ as stabilizer

Butanedioic acid,2-methylene-, 1,4-dimethyl ester

DiMethyl itaconate (stab. with hydroquinone)

DiMethyl Itaconate (stabilized with HQ), 98.0%(GC)

Itaconate (stabiL

ized with HQ)

ITACONIC ACID DIMETHYL ESTER

DIMETHYL 2-METHYLENESUCCINATE

DIMETHYL ITACONATE

DIMETHYL METHYLENESUCCINATE

METHYL ITACONATE

Butanedioic acid, 2-methylene-, dimethyl ester

methylene-butanedioicacid,dimethylester

Methylenesuccinic acid, dimethyl ester

methylenesuccinicaciddimethylester

Succinic acid, methylene-, dimethyl ester

2-AMINO-6-CHLOROPURINE, 99+%

Butanedioic acid, methylene-, dimethyl ester

Dimethyl Itaconate (stabilized with HQ)

Dimethyl methylenebutanedioate

2-METHYLENE-SUCCINIC ACID DIMETHYL ESTER

DimethylItaconate(stabilizedwithHQ)&gt

dimethyl 2-methylenebutanedioate

Dimethyl itaconate,contains ~3ppm HQ as stabilizer

Dimethyl itaconate, 10 mM in DMSO

109533-100G

617-52-7

CH3O2CCH2CCH2CO2CH3

C7 to C8

Carbonyl Compounds

Building Blocks

Organic Building Blocks

Ketones

C6 to C7

Esters

C6 to C7

Esters

C7 to C8

Carbonyl Compounds

Ketones

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