ChemicalBook > CAS DataBase List > methyl orsellinate

methyl orsellinate

Product Name
methyl orsellinate
CAS No.
3187-58-4
Chemical Name
methyl orsellinate
Synonyms
Methyl;METHYL ORSELLINATE;Methyl o-orsellinate;Orsellinic acid methyl;o-Orsellinic acid methyl;6-Methyl-β-resorcylicacidmethyl;6-Methyl-β-resorcylic acid methyl;BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
CBNumber
CB31484897
Molecular Formula
C9H10O4
Formula Weight
182.17
MOL File
3187-58-4.mol
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methyl orsellinate Property

Melting point:
141-142℃
Boiling point:
339℃
Density 
1.296
Flash point:
138℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
8.27±0.23(Predicted)
color 
White to Off-White
InChI
InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
InChIKey
NCCWCZLEACWJIN-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=C(C)C=C(O)C=C1O
LogP
2.380 (est)
EPA Substance Registry System
Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester (3187-58-4)
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Safety

HS Code 
2918290090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M302230
Product name
Methyl2,4-Dihydroxy-6-methylbenzoate
Packaging
50mg
Price
$70
Updated
2021/12/16
TRC
Product number
M302230
Product name
Methyl2,4-Dihydroxy-6-methylbenzoate
Packaging
500mg
Price
$205
Updated
2021/12/16
TRC
Product number
M302230
Product name
Methyl2,4-Dihydroxy-6-methylbenzoate
Packaging
2.5g
Price
$870
Updated
2021/12/16
ChemScene
Product number
CS-0023752
Product name
Methylorsellinate
Packaging
250mg
Price
$179
Updated
2021/12/16
ChemScene
Product number
CS-0023752
Product name
Methylorsellinate
Packaging
1g
Price
$309
Updated
2021/12/16
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methyl orsellinate Chemical Properties,Usage,Production

Uses

Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.

Definition

ChEBI: Orsellinic acid methyl ester is a hydroxybenzoic acid. It has a role as a metabolite.

Biochem/physiol Actions

Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.

methyl orsellinate Preparation Products And Raw materials

Raw materials

Preparation Products

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methyl orsellinate Suppliers

Xiamen Work-For-World Medcine Co., Ltd
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View Lastest Price from methyl orsellinate manufacturers

Zhengzhou Anbu Chem Co.,Ltd
Product
METHYL ORSELLINATE 3187-58-4
Price
US $0.00/KG
Min. Order
0.1KG
Purity
98%
Supply Ability
1000KGS
Release date
2023-10-26
Shaanxi Dideu Medichem Co. Ltd
Product
Methyl orsellinate 3187-58-4
Price
US $1.00/Kg
Min. Order
1Kg
Purity
98%
Supply Ability
20T
Release date
2024-07-09
PNP Biotech Co. Ltd
Product
Methyl 2,4-dihydroxy-6-methylbenzoate 3187-58-4
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2023-06-06

3187-58-4, methyl orsellinateRelated Search:


  • Orsellinic acid methyl
  • 6-Methyl-β-resorcylic acid methyl
  • Methyl o-orsellinate
  • o-Orsellinic acid methyl
  • BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
  • 6-Methyl-β-resorcylicacidmethyl
  • METHYL ORSELLINATE
  • Methyl
  • 3187-58-4
  • Aromatic Esters