2-Methyl-5-chloromethylpyridine hydrochloride
- Product Name
- 2-Methyl-5-chloromethylpyridine hydrochloride
- CAS No.
- 106651-81-4
- Chemical Name
- 2-Methyl-5-chloromethylpyridine hydrochloride
- Synonyms
- 5-(CHLOROMETHYL)-2-METHYLPYRIDINEHCL;2-Methyl-5-chloromethylpyridine, HCl;-Methyl-5-chloromethylpyridine hydrochloride;5-Chloromethyl-2-methylpyridine hydrochloride;3-Chloromethyl-6-methylpyridine hydrochloride;2-Methyl-5-chloromethylpyridine hydrochloride
- CBNumber
- CB31503961
- Molecular Formula
- C7H9Cl2N
- Formula Weight
- 178.06
- MOL File
- 106651-81-4.mol
2-Methyl-5-chloromethylpyridine hydrochloride Property
- Melting point:
- 133-135 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B419373
- Product name
- 5-(Chloromethyl)-2-methylpyridineHydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B419373
- Product name
- 5-(Chloromethyl)-2-methylpyridineHydrochloride
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- Z3855
- Product name
- 5-(Chloromethyl)-2-methylpyridinehydrochloride
- Packaging
- 250mg
- Price
- $111
- Updated
- 2021/12/16
- Product number
- Z3855
- Product name
- 5-(Chloromethyl)-2-methylpyridinehydrochloride
- Packaging
- 1g
- Price
- $193
- Updated
- 2021/12/16
- Product number
- 119962
- Product name
- 5-(Chloromethyl)-2-methylpyridine hydrochloride
- Purity
- 95+%
- Packaging
- 1g
- Price
- $244
- Updated
- 2021/12/16
2-Methyl-5-chloromethylpyridine hydrochloride Chemical Properties,Usage,Production
Synthesis
34107-46-5
106651-81-4
A solution of 6-methyl-3-methanol pyridine (52.2 g, 424 mmol) was prepared by dissolving it in 190 ml of toluene and 60 ml of CHCl3 as starting material. This solution was slowly added dropwise to 44 ml of toluene solution containing SOCl2 (34 ml, 469 mmol), and the internal temperature of the reaction system was controlled to be maintained between 23°C and 35°C during the dropwise addition. After the dropwise addition, the reaction mixture was stirred vigorously at room temperature for 1 hour. Subsequently, all solvents were removed by distillation under reduced pressure with a water pump. The brown precipitate obtained was resuspended with toluene, rapidly filtered and washed three times with toluene. Finally, the product was dried in a desiccator (vacuum via aspirator) to give 5-(chloromethyl)-2-methylpyridine hydrochloride 72.1 g (405 mmol, 96% yield) as a brown solid.
References
[1] Patent: US2005/124586, 2005, A1. Location in patent: Page/Page column 7
[2] Patent: WO2012/82689, 2012, A1. Location in patent: Page/Page column 129
[3] Journal of Medicinal Chemistry, 1991, vol. 34, # 3, p. 1028 - 1036
[4] Patent: US2010/143301, 2010, A1. Location in patent: Page/Page column 108
[5] Patent: WO2015/163485, 2015, A1. Location in patent: Paragraph 0524
2-Methyl-5-chloromethylpyridine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methyl-5-chloromethylpyridine hydrochloride Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
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View Lastest Price from 2-Methyl-5-chloromethylpyridine hydrochloride manufacturers
- Product
- -Methyl-5-chloromethylpyridine hydrochloride 106651-81-4
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-12