TALIPEXOLE

Product Name: TALIPEXOLE
CAS No.: 101626-70-4
Chemical Name: TALIPEXOLE
Synonyms: Domin;Talipexol;TALIPEXOLE;Talipexolum;Talipexolum [latin];Talipexol [spanish];TALIPEXOLE USP/EP/BP;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine;6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine;6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
CBNumber: CB3153213
Molecular Formula: C10H15N3S
Formula Weight: 209.31
MOL File: 101626-70-4.mol

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TALIPEXOLE Property

Boiling point:: 364.6±37.0 °C(Predicted)
Density: 1.167±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 7.22±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 5MG
Price: $490
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 10MG
Price: $520
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 50MG
Price: $920
Updated: 2021/12/16

AvaChem

Product number: 2567B
Product name: Talipexole
Packaging: 1g
Price: $2900
Updated: 2021/12/16

Crysdot

Product number: CD31004840
Product name: Talipexole
Purity: 98+%
Packaging: 5mg
Price: $76
Updated: 2021/12/16

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TALIPEXOLE Chemical Properties,Usage,Production

Description

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D₂ receptors with no D₁ receptor activity. It is a clonidine-like α₂-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT₃ receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

Definition

ChEBI: 6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine is an azepine.

brand name

Domin

TALIPEXOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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TALIPEXOLE Suppliers

China 19 Europe 2 Germany 1 United Kingdom 4 United States 12 Global 38

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Eurolabs Limited

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

101626-70-4, TALIPEXOLERelated Search:

ARANIDIPINE Bendamustine Donepezil CALYXOL ISO-TALIPEXOLE, DIHYDROCHLORIDE TALIPEXOLE DIDHYDROCHLORIDE,Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride,talipexole hydrochloride 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE TALIPEXOLE 2-(THIAZOL-4-YL)ETHYLAMINE AMTHAMINE DIHYDROBROMIDE 5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE

TALIPEXOLE

5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine

Domin

6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine

6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine

Talipexol

Talipexol [spanish]

Talipexolum

Talipexolum [latin]

4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-

TALIPEXOLE USP/EP/BP

6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine

101626-70-4