TALIPEXOLE

Product Name: TALIPEXOLE
CAS No.: 101626-70-4
Chemical Name: TALIPEXOLE
Synonyms: Domin;Talipexol;TALIPEXOLE;Talipexolum;Talipexolum [latin];Talipexol [spanish];TALIPEXOLE USP/EP/BP;6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine;6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine;6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine
CBNumber: CB3153213
Molecular Formula: C10H15N3S
Formula Weight: 209.31
MOL File: 101626-70-4.mol

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TALIPEXOLE Property

Boiling point:: 364.6±37.0 °C(Predicted)
Density: 1.167±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 7.22±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 5MG
Price: $490
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 10MG
Price: $520
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0009175
Product name: TALIPEXOLE
Purity: 95.00%
Packaging: 50MG
Price: $920
Updated: 2021/12/16

Crysdot

Product number: CD31004840
Product name: Talipexole
Purity: 98+%
Packaging: 5mg
Price: $76
Updated: 2021/12/16

Crysdot

Product number: CD31004840
Product name: Talipexole
Purity: 98+%
Packaging: 10mg
Price: $102
Updated: 2021/12/16

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TALIPEXOLE Chemical Properties,Usage,Production

Description

Domin was launched in Japan for Parkinson's disease. The compound is readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its antiparkinson activity resides in the fact that talipexole is a selective agonist for presynaptic dopamine D₂ receptors with no D₁ receptor activity. It is a clonidine-like α₂-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most widely used dopamine angonist. Also it is 70 times more potent than bromocriptine and has a more rapid onset of action. In addition to its anti-tremor activity there was a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT₃ receptor antagonistic activity. Its metabolites have no biological activity, there was no development of tolerence and its effect could be enhanced by L-dopa.

Originator

Boehringer Ingelheim (Germany)

Definition

ChEBI: 6-prop-2-enyl-4,5,7,8-tetrahydrothiazolo[4,5-d]azepin-2-amine is an azepine.

brand name

Domin

TALIPEXOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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TALIPEXOLE Suppliers

China 19 Europe 2 Germany 1 United Kingdom 4 United States 12 Global 38

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Alfa Chemistry

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Email: Info@alfa-chemistry.com
Country: United States
ProdList: 24072
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

TargetMol Chemicals Inc.

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Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

Waterstone Technology, LLC

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Country: United States
ProdList: 6786
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2A PharmaChem USA

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Country: United States
ProdList: 6137
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3B Scientific Corporation

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ProdList: 6718
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AK Scientific, Inc.

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Country: United States
ProdList: 6347
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Fine Chem Trading LTD

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Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
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101626-70-4, TALIPEXOLERelated Search:

ARANIDIPINE Bendamustine Donepezil CALYXOL ISO-TALIPEXOLE, DIHYDROCHLORIDE TALIPEXOLE DIDHYDROCHLORIDE,Talipexole, 5,6,7,8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4,5-d]azepine-2-amine dihydrochloride,talipexole hydrochloride 2-(4-METHYL-THIAZOL-5-YL)-ETHYLAMINE TALIPEXOLE 2-(THIAZOL-4-YL)ETHYLAMINE AMTHAMINE DIHYDROBROMIDE 5,6,7,8-TETRAHYDRO-4H-THIAZOLO[4,5-D]AZEPINE 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE

TALIPEXOLE

5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine

Domin

6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine

6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine

Talipexol

Talipexol [spanish]

Talipexolum

Talipexolum [latin]

4H-Thiazolo[4,5-d]azepin-2-amine, 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-

TALIPEXOLE USP/EP/BP

6-Allyl-5,6,7,8-tetrahydro-4H-[1,3]thiazolo[4,5-d]azepin-2-amine

101626-70-4