Dexamethasone sodium phosphate
- Product Name
- Dexamethasone sodium phosphate
- CAS No.
- 55203-24-2
- Chemical Name
- Dexamethasone sodium phosphate
- Synonyms
- Veterinary Medicine D Examethasone CAS 55203-24-2;DEXAMETHASON SODIUM PHOSPHATE;DEXAMETHASONE PHOSPHATE SODIUM;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-PHOSPHATE, DISODIUM SALT;Niclofolano;Niclofolanum;DEXAMETHASONE SODIUM PHOSPHATE;Dexadreson|||Dexagro|||Dalalone;Dexamethasone sodium phosphate(Abs);DEXAMETHASONE PHOSPHATE DISODIUM SALT
- CBNumber
- CB3153738
- Molecular Formula
- C22H28FNa2O8P
- Formula Weight
- 516.4
- MOL File
- 55203-24-2.mol
Dexamethasone sodium phosphate Property
- Melting point:
- 204-206°C (dec.)
- storage temp.
- 2-8°C
- solubility
- H2O: 50 mg/mL, clear, faintly yellow
- form
- Solid
- color
- white to off-white
- Stability:
- Hygroscopic
- EPA Substance Registry System
- Pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17-dihydroxy-16- methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.alpha.)-(55203-24-2)
N-Bromosuccinimide Price
- Product number
- B1588
- Product name
- Dexamethasone Sodium Phosphate
- Packaging
- 5g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- MT-49865
- Product name
- Dexamethasonsodiumphosphate
- Purity
- 98%
- Packaging
- 25g
- Price
- $320
- Updated
- 2021/12/16
Dexamethasone sodium phosphate Chemical Properties,Usage,Production
Uses
Dexamethasone Sodium Phosphate is an inducer of apoptosis and inhibitor of the sodium phosphate symporter.
Definition
ChEBI: Dexamethasone sodium phosphate is an organic sodium salt which is the disodium salt of dexamethasone phosphate. It has a role as a glucocorticoid receptor agonist. It contains a dexamethasone phosphate(2-).
brand name
Decadron (Merck); Dexacen (Cent); Dexacort (UCB); Dexair (Pharmafair); Hexadrol (Organon); Maxidex (Alcon).
Synthesis
Preparation of dexamethasone sodium phosphate for injection. Synthesis: Using dexamethasone acetate epoxide as the starting material, steps include a ring-opening reaction (HF/DMF, -10C), recrystallization (methanol), base-catalyzed hydrolysis (Na2CO3/methanol, 20C), esterification with pyrophosphoryl chloride (THF), and neutralization/salt formation (NaOH/methanol, 20C) to yield a dexamethasone sodium phosphate solution, which is recrystallized again to give crystals. The crystals are dried and ball-milled, then mixed with glucose, disodium hydrogen phosphate, and sodium dihydrogen phosphate. This mixture is dissolved in water for injection, ethanol and activated carbon are added, the solution is kept warm, and then filtered.
Dexamethasone sodium phosphate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dexamethasone sodium phosphate manufacturers
- Product
- Dexamethasone sodium phosphate 55203-24-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- CEP/EP/USP
- Supply Ability
- 20TONS
- Release date
- 2025-07-09
- Product
- Dexamethasone sodium phosphate 55203-24-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 97%-102%
- Supply Ability
- 500KG
- Release date
- 2021-06-01
- Product
- Dexamethasone sodium phosphate 55203-24-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%
- Supply Ability
- 1tons
- Release date
- 2024-04-26