tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate

Product Name: tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
CAS No.: 167081-37-0
Chemical Name: tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate
Synonyms: trans-1-(Boc-aMino)-3-(hy...;tert-Butyl (trans-3-(hydroxymethyl);trans-3-(Boc-amino)cyclobutanemethanol,97%;trans-3-(Boc-aMino)cyclobutaneMethanol, 97%;BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;trans-1-(Boc-aMino)-3-(hydroxyMethyl)cyclobutane;tert-butyl N-[3-(hydroxymethyl)cyclobutyl]carbamat;TERT-BUTYL TRANS-3-HYDROXYMETHYLCYCLOBUTYLCARBAMATE;tert-butyl (1r,3r)-3-(hydroxymethyl)cyclobutylcarbamate;trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane - SB7652
CBNumber: CB3158733
Molecular Formula: C10H19NO3
Formula Weight: 201.26
MOL File: 167081-37-0.mol

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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Property

Boiling point:: 317.9±11.0 °C(Predicted)
Density: 1.08±0.1 g/cm3(Predicted)
pka: 12.42±0.40(Predicted)

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Safety

HS Code: 2922500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: H62719
Product name: trans-3-(Boc-amino)cyclobutanemethanol
Purity: 97%
Packaging: 250mg
Price: $184.65
Updated: 2024/03/01

Alfa Aesar

Product number: H62719
Product name: trans-3-(Boc-amino)cyclobutanemethanol
Purity: 97%
Packaging: 1g
Price: $550.65
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FB53711
Product name: Tert-Butyl Trans-3-Hydroxymethylcyclobutylcarbamate
Packaging: 500mg
Price: $580
Updated: 2021/12/16

Matrix Scientific

Product number: 089423
Product name: tert-Butyl trans-3-hydroxymethylcyclobutylcarbamate
Packaging: 1g
Price: $1183
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4256-1-27
Product name: trans-1-(Boc-amino)-3-(hydroxymethyl)cyclobutane
Packaging: 5G
Price: $1250
Updated: 2021/12/16

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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Chemical Properties,Usage,Production

Synthesis

To a stirred solution of methyl (1R,3R)-3-((tert-butoxycarbonyl)amino)cyclobutane-1-carboxylate (1.0 g, 4.4 mmol) in THF (20 mL) was added 3M lithium borohydride (9 mL, 9 mmol) at 0° C. Then the reaction mixture was heated and stirred at 60° C for 3 h. The reaction mixture was then transferred into dilute NaOH and the resulting mixture was extracted using ethyl acetate (3×50 mL). The combined organic layer was dried over anhydrous sodium sulfate and filtered. The filtrate was evaporated under reduced pressure and the crude product was purified using silica gel column chromatography (3% MeOH-DCM) to give tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate as a white solid (0.8 g, 91%).

Reactions

Tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate is an crucial organic compound that can be used to synthesize 3-Amino-cyclobutaneMethanol hydrochloride.

tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl (trans-3-(hydroxymethyl)cyclobutyl)carbamate Suppliers

China 43 Europe 1 India 1 United Kingdom 2 United States 11 Global 58

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