ChemicalBook > CAS DataBase List > (S)-N-Boc-3-aminobutyric acid

(S)-N-Boc-3-aminobutyric acid

Product Name
(S)-N-Boc-3-aminobutyric acid
CAS No.
158851-30-0
Chemical Name
(S)-N-Boc-3-aminobutyric acid
Synonyms
-HoAla-OH;Boc--HoAla-OH;Boc-b-HoAla-OH;BOC-SS-HOMOALA;Boc-β-HoAla-OH;CAS:158851-30-0;Boc-L-β-Homo-Ala;Boc-p-HomoAla-OH;Boc-beta-HAla-OH;Boc-L-b-HoAla-OH
CBNumber
CB3158869
Molecular Formula
C9H17NO4
Formula Weight
203.24
MOL File
158851-30-0.mol
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(S)-N-Boc-3-aminobutyric acid Property

Melting point:
99 °C
Boiling point:
339.5±25.0 °C(Predicted)
Density 
1.101±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
4.43±0.10(Predicted)
color 
White to light yellow
optical activity
Consistent with structure
Water Solubility 
Slightly soluble in water.
BRN 
6800577
InChI
InChI=1S/C9H17NO4/c1-6(5-7(11)12)10-8(13)14-9(2,3)4/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m0/s1
InChIKey
PYNDHEONPQYIAN-LURJTMIESA-N
SMILES
C(O)(=O)C[C@@H](NC(OC(C)(C)C)=O)C
CAS DataBase Reference
158851-30-0(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
14974
Product name
Boc-β-Homoala-OH
Purity
≥98.0% (TLC)
Packaging
1g
Price
$197
Updated
2023/06/20
TRC
Product number
B656210
Product name
Boc-β-Homoala-OH
Packaging
1g
Price
$325
Updated
2021/12/16
Chem-Impex
Product number
12789
Product name
Boc-L-β-homoalanine,95%(NMR)
Purity
95%(NMR)
Packaging
250MG
Price
$22.4
Updated
2021/12/16
AK Scientific
Product number
V1057
Product name
Boc-L-beta-homoalanine
Packaging
250mg
Price
$24
Updated
2021/12/16
Matrix Scientific
Product number
042280
Product name
Boc-L-beta-homoalanine
Packaging
500mg
Price
$29
Updated
2021/12/16
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(S)-N-Boc-3-aminobutyric acid Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

(S)-3-(Boc-amino)butyric acid is used for the syntheses of aza-analogues of macrosphelides, synthesis of hybrid peptides with 12/10-helix, and in the synthesis of potentially pharmaceutically active products for the treatment of auto-immune and inflammatory diseases.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

118173-26-5

158851-30-0

Under argon protection, sodium dihydrogen phosphate (7.0 g) and 34.5% aqueous hydrogen peroxide solution (20 mL) were sequentially added to a solution of tert-butyl (S)-(4-oxobutan-2-yl)carbamate (7.3 g, 39.0 mmol) in acetonitrile (50 mL), and the reaction mixture was stirred at 0 °C for 10 min. Subsequently, a solution of sodium chlorite (6.0 g) in water (20 mL) was added dropwise to the reaction system and stirring was continued at 0 °C for 1 hour. Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution and the aqueous phase was washed with dichloromethane. The aqueous layer was acidified with 10% hydrochloric acid and extracted with dichloromethane, the organic phase was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The resulting residue was identified by 1H-NMR as carboxylic acid (8) (6.0 g, 29.6 mmol, 76% yield), which could be used in the next reaction without further purification.

References

[1] Tetrahedron, 2011, vol. 67, # 40, p. 7681 - 7685

(S)-N-Boc-3-aminobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-N-Boc-3-aminobutyric acid Suppliers

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View Lastest Price from (S)-N-Boc-3-aminobutyric acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
(S)-N-Boc-3-aminobutyric acid 158851-30-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
(S)-N-Boc-3-aminobutyric acid 158851-30-0
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

158851-30-0, (S)-N-Boc-3-aminobutyric acidRelated Search:

tert-Butanol Phenprobamate tert-Butyl peroxyacetate 4-Aminobutyric acid EC 2.6.1.2 D-Alanine Stearic acid Butyric Acid Ethyl 2-(Chlorosulfonyl)acetate DL-2-Aminobutyric acid DL-3-Aminobutyric acid L(+)-2-Aminobutyric acid Folic acid Citric acid Ascoric Acid r-Amino Butryric Acid Boc-D-aspartic acid 4-benzyl ester Boc-D-aspartic acid 4-cyslohexyl ester

  • BOC-ALA-(C*CH2)OH
  • BOC-BETA-HOALA-OH
  • BOC-BETA-HOMOALA-OH
  • BOC-L-BETA-HOMOALANINE
  • BOC PROTECTED (S)-B-AMINOBUTYRIC ACID
  • (S)-BOC-B2-HOALA-OH
  • (S)-BOC-BETA2-HAL-OH
  • (S)-BOC-BETA2-HOMOALANINE
  • (S)-N-(TERT-BUTOXYCARBONYL)-3-AMINOBUTYRIC ACID
  • (S)-N-BOC-3-AMINOBUTYRIC ACID
  • (S)-3-(BOC-AMINO)BUTYRIC ACID
  • RARECHEM DK TD C012
  • N-BETA-T-BUTOXYCARBONYL-L-BETA-HOMOALANINE
  • Boc-β-homoalanine
  • Boc-β-Homoala-OH
  • Boc-L-Homoalanine
  • Boc-BETA-HOMOALANINE
  • Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3S)- (9CI)
  • Boc-L-b-homoalanine
  • Boc-b-HoAla-OH
  • BOC-SS-HOMOALA
  • Boc-L-beta-HAla-OH
  • N-beta-(t-Butyloxycarbonyl)-L-homoalanine
  • BOC-SS-HOMOALANINE
  • Boc-L-β-Homo-Ala-OH
  • Boc--HoAla-OH
  • (S)-3-(tert-Butoxycarbonylamino)butyric acid
  • (S)-3-(Boc-amino)butyric acid, Boc-L-β-homoalanine
  • Boc-L-beta-Homo-Ala
  • BOC-B-HOMOALANINE
  • N-Boc-L-AMinobutyric acid
  • (S)-3-((tert-Butoxycarbonyl)aMino)butanoic acid
  • Boc-(S)-β3-HAla-OH
  • -HoAla-OH
  • (3S)-3-(Boc-amino)butanoic acid
  • Boc-L-β-homoalanine≥ 95% (NMR)
  • (Tert-Butoxy)Carbonyl L-β-HoAla-OH
  • Boc-beta-Homoala-OH >=98.0% (TLC)
  • Boc-L-β-Homo-Ala
  • (3S)-3-[(TERT-BUTOXYCARBONYL)AMINO]BUTANOIC ACID
  • Butanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (3S)-
  • Boc-L-β-Homoalanine
  • Boc-β-HoAla-OH
  • Boc-p-HomoAla-OH
  • (S)-N-Boc-3-aminobutyric acid USP/EP/BP
  • (3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
  • CAS:158851-30-0
  • (S)-N-Boc-3-aminobutyric acid, 98%min
  • Boc-beta-HAla-OH
  • Boc-L-b-HoAla-OH
  • (3S)-3-[N-BOC-Amino]butanoic acid
  • 158851-30-0
  • Beta-Amino Acids
  • Peptide Synthesis
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • pharmacetical
  • β-Homo Amino Acids