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Ethyl 2-methylthiazole-4-carboxylate

Product Name
Ethyl 2-methylthiazole-4-carboxylate
CAS No.
6436-59-5
Chemical Name
Ethyl 2-methylthiazole-4-carboxylate
Synonyms
BUTTPARK 29\06-83;ETHYL 2-METHYLTHIAZO;2-Methylthiazole-4-carboxylate;ETHYL 2-METHYLTHIAZOL-4-CARBOXYLATE;ETHYL 2-METHYLTHIAZOLE-4-CARBOXYLATE;methyl 2-methylthiazole-4-carboxylate;4-(Ethoxycarbonyl)-2-methyl-1,3-thiazole;ETHYL 2-METHYL-1,3-THIAZOLE-4-CARBOXYLATE;Ethyl 2-methyl-1,3-thiazole-4-carboxylate ,98%;2-methylthiazole-4-carboxylic acid ethyl ester
CBNumber
CB3163100
Molecular Formula
C7H9NO2S
Formula Weight
171.22
MOL File
6436-59-5.mol
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Ethyl 2-methylthiazole-4-carboxylate Property

Melting point:
54-58 °C
Boiling point:
242.1±13.0 °C(Predicted)
Density 
1.198±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
1.10±0.10(Predicted)
form 
solid
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C7H9NO2S/c1-3-10-7(9)6-4-11-5(2)8-6/h4H,3H2,1-2H3
InChIKey
QWWPUBQHZFHZSF-UHFFFAOYSA-N
SMILES
S1C=C(C(OCC)=O)N=C1C
CAS DataBase Reference
6436-59-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29341000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
716308
Product name
Ethyl 2-methylthiazole-4-carboxylate
Purity
97%
Packaging
1g
Price
$50.2
Updated
2023/06/20
Sigma-Aldrich
Product number
716308
Product name
Ethyl 2-methylthiazole-4-carboxylate
Purity
97%
Packaging
5g
Price
$180
Updated
2023/06/20
TRC
Product number
E925778
Product name
Ethyl 2-methylthiazole-4-carboxylate
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
E925778
Product name
Ethyl 2-methylthiazole-4-carboxylate
Packaging
500mg
Price
$65
Updated
2021/12/16
Usbiological
Product number
448944
Product name
Ethyl 2-methylthiazole-4-carboxylate
Packaging
100mg
Price
$305
Updated
2021/12/16
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Ethyl 2-methylthiazole-4-carboxylate Chemical Properties,Usage,Production

Chemical Properties

light yellowto brownpowde

Uses

Ethyl 2-methylthiazole-4-carboxylate is a reactant used in the synthesis of 2,?4,?5-?trisubstituted thiazoles as antituberculosis agents effective against drug resistant tuberculosis.

Synthesis

70-23-5

62-55-5

6436-59-5

Ethyl 2-methylthiazole-4-carboxylate was synthesized from ethyl 3-bromopyruvate and thioacetamide in ethanol (EtOH) at 250 W power, 25 kHz frequency, flow rate controlled at 2 mL/min, and reaction time of 1.5 hours.

References

[1] Journal of Organic Chemistry, 1997, vol. 62, # 12, p. 3804 - 3805
[2] Organic Letters, 2008, vol. 10, # 8, p. 1565 - 1568
[3] Journal of Organic Chemistry, 2001, vol. 66, # 19, p. 6410 - 6424
[4] Angewandte Chemie - International Edition, 2008, vol. 47, # 46, p. 8950 - 8953
[5] Patent: US2010/249404, 2010, A1. Location in patent: Page/Page column 11

Ethyl 2-methylthiazole-4-carboxylate Preparation Products And Raw materials

Raw materials

Ethanol Ethyl bromopyruvate Ethyl acetate Thioacetamide PETROLEUM ETHER

Preparation Products

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Ethyl 2-methylthiazole-4-carboxylate Suppliers

Belgium 1 China 159 Germany 3 India 6 United Kingdom 9 United States 26 Global 204
Anhui Yongsheng Pharmaceutical Technology Co., Ltd
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181-3307-5798 18017383231
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983544897@qq.com
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China
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J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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market03@meryer.com
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China
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40228
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Alfa Aesar
Tel
400-6106006
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021-67582001/03/05
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saleschina@alfa-asia.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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China
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Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.
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21-54820552 18964669552
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086-21-64964478
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188738128@qq.com
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
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11035
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View Lastest Price from Ethyl 2-methylthiazole-4-carboxylate manufacturers

Career Henan Chemical Co
Product
ETHYL 2-METHYLTHIAZOLE-4-CARBOXYLATE 6436-59-5
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10TON
Release date
2018-12-18

6436-59-5, Ethyl 2-methylthiazole-4-carboxylateRelated Search:

2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER 2-P-TOLYL-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER ETHYL 2-METHYLTHIAZOLE-4-CARBOXYLATE ETHYL 2-(2-THIENYL)-1,3-THIAZOLE-4-CARBOXYLATE Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate ETHYL 2-(TRIFLUOROMETHYL)THIAZOLE-5-CARBOXYLATE Ethyl 2-amino-4-methylthiazole-5-carboxylate ETHYL 2-BROMO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE ETHYL 4-METHYL-2-PHENYL-1,3-THIAZOLE-5-CARBOXYLATE ETHYL 2-AMINO-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE HYDROCHLORIDE 4-TRIFLUOROMETHYLTHIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER ETHYL 2,4-DIMETHYLTHIAZOLE-5-CARBOXYLATE ETHYL 4-METHYLTHIAZOLE-5-CARBOXYLATE ETHYL 4-METHYLTHIAZOLE-5-CARBOXYLATE Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate ETHYL THIAZOLE-4-CARBOXYLATE 4-Thiazolecarboxylic acid

  • BUTTPARK 29\06-83
  • ETHYL 2-METHYLTHIAZOL-4-CARBOXYLATE
  • ETHYL 2-METHYLTHIAZOLE-4-CARBOXYLATE
  • ETHYL 2-METHYL-1,3-THIAZOLE-4-CARBOXYLATE
  • Ethyl 2-methyl-1,3-thiazole-4-carboxylate ,98%
  • ETHYL 2-METHYLTHIAZO
  • 4-Thiazolecarboxylicacid, 2-methyl-, ethyl ester
  • 2-methylthiazole-4-carboxylic acid ethyl ester
  • methyl 2-methylthiazole-4-carboxylate
  • 4-(Ethoxycarbonyl)-2-methyl-1,3-thiazole
  • 2-Methylthiazole-4-carboxylate
  • Ethyl 2-methylthiazole-4-carboxylate≥ 98% (GC)
  • Ethyl 2-Methylthiazole-4-Carboxylate(WX618254)
  • JR-13766, Ethyl 2-methylthiazole-4-carboxylate, 97%
  • 6436-59-5
  • Building Blocks
  • C3 to C7
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Thiazoles