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2-CHLORO-6-HYDROXYBENZALDEHYDE

Product Name
2-CHLORO-6-HYDROXYBENZALDEHYDE
CAS No.
18362-30-6
Chemical Name
2-CHLORO-6-HYDROXYBENZALDEHYDE
Synonyms
6-CHLOROSALICYLALDEHYDE;6-chloro salicyaldehyde;4-Bromo-5-fluoroacetophenone;2-CHLORO-6-HYDROXYBENZALDEHYDE;2-chloro-6-hydroxy-benzaldehyd;6-Chloro-2-hydroxybenzaldehyde;Benzaldehyde, 2-chloro-6-hydroxy-;6-Chlorosalicylaldehyde, 3-Chloro-2-formylphenol;6-chloro salicyaldehyde 2-chloro-6-hydroxybenzaldehyde
CBNumber
CB3169142
Molecular Formula
C7H5ClO2
Formula Weight
156.57
MOL File
18362-30-6.mol
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2-CHLORO-6-HYDROXYBENZALDEHYDE Property

Melting point:
51-55℃
Boiling point:
223.1±20.0 °C(Predicted)
Density 
1.404±0.06 g/cm3(Predicted)
Flash point:
107℃
storage temp. 
2-8°C
pka
7.21±0.10(Predicted)
form 
powder to crystal
color 
White to Light yellow to Light orange
InChI
InChI=1S/C7H5ClO2/c8-6-2-1-3-7(10)5(6)4-9/h1-4,10H
InChIKey
MVTWVXYIKIVAOJ-UHFFFAOYSA-N
SMILES
C(=O)C1=C(O)C=CC=C1Cl
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41
Safety Statements 
26-39
WGK Germany 
3
HS Code 
2912490090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
715123
Product name
2-Chloro-6-hydroxybenzaldehyde
Purity
97%
Packaging
500mg
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
C3526
Product name
2-Chloro-6-hydroxybenzaldehyde
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$30
Updated
2025/07/31
TCI Chemical
Product number
C3526
Product name
2-Chloro-6-hydroxybenzaldehyde
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$121
Updated
2025/07/31
TRC
Product number
C368258
Product name
2-Chloro-6-hydroxybenzaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR42100
Product name
2-Chloro-6-hydroxybenzaldehyde
Packaging
1g
Price
$79
Updated
2021/12/16
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2-CHLORO-6-HYDROXYBENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

387-45-1

18362-30-6

The general procedure for the synthesis of 6-chlorosalicylaldehyde from 2-chloro-6-fluoro-benzaldehyde was as follows: potassium hydroxide (10 g) was slowly added to a stirred solution of 2-chloro-6-fluoro-benzaldehyde (14.0 g, 88.3 mmol) in dimethyl sulfoxide (20 mL) at 0 °C. Subsequently, the reaction mixture was gradually warmed to room temperature and stirred continuously for 18 hours. Upon completion of the reaction, the reaction mixture was diluted with 100 mL of water and the pH was adjusted with concentrated hydrochloric acid to 2. The precipitate was collected by filtration, washed twice successively with 100 mL of water, and then dried with anhydrous sodium sulfate to afford the crude product, which was used in the subsequent reaction without further purification. The final yield was 8.5 g in 62% yield. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) with δppm 6.65-7.02 (m, 2H), 7.39-7.47 (m, 1H), 10.41 (s, 1H), 11.95 (s, 1H).

References

[1] European Journal of Organic Chemistry, 2018, vol. 2018, # 25, p. 3348 - 3351
[2] Patent: WO2012/87229, 2012, A1. Location in patent: Page/Page column 14
[3] Patent: US2008/171754, 2008, A1. Location in patent: Page/Page column 89
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993, # 12, p. 1345 - 1358
[5] Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie, 1972, vol. 27, p. 663 - 674

2-CHLORO-6-HYDROXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Chloroform Dichloromethane 3-Chlorophenol PETROLEUM ETHER Calcium hydroxide Sodium carbonate

Preparation Products

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2-CHLORO-6-HYDROXYBENZALDEHYDE Suppliers

Americas 1 China 129 Europe 1 Germany 3 India 3 Japan 1 The Netherlands 1 United Kingdom 10 United States 15 Global 164
Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
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View Lastest Price from 2-CHLORO-6-HYDROXYBENZALDEHYDE manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
2-CHLORO-6-HYDROXYBENZALDEHYDE 18362-30-6
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-10-10
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-CHLORO-6-HYDROXYBENZALDEHYDE 18362-30-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-19
Shaanxi Dideu Medichem Co. Ltd
Product
2-chloro-6-hydroxybenzaldehyde 18362-30-6
Price
US $0.00-0.00/g
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15

18362-30-6, 2-CHLORO-6-HYDROXYBENZALDEHYDERelated Search:

4-TERT-BUTYL-5-CHLORO-2-HYDROXYBENZALDEHYDE 3,5,6-Trichlorosalicylic acid 2,4-DICHLORO-6-HYDROXYBENZALDEHYDE DICAMBA METHYL ESTER 3,6-DICHLORO-2-HYDROXY BENZOIC ACID Dicamba 2-chloro-6-methoxybenzoic acid 2,5-Dichloro-3-hydroxy-6-methoxybenzoic acid Oxyclozanide 2-CHLORO-4-HYDROXYBENZALDEHYDE,2-CHLORO-4-HYDROXYBENZALDEHYDE 99% & 4-Chloro-2-hydroxybenzaldehyde 3,5-DICHLOROSALICYLALDEHYDE 3-Chloro-2-hydroxybenzaldehyde2-Chloro-6-formylphenol 2-CHLORO-4-HYDROXYBENZALDEHYDE,3-CHLORO-4-HYDROXYBENZALDEHYDE,3-Chloro-4-hydroxybenzaldehyde 98%,3-Chloro-4-hydroxybenzaldehyde, 99+% 3-BROMO-5-CHLORO-2-HYDROXYBENZALDEHYDE 98%,3-BROMO-5-CHLORO-2-HYDROXYBENZALDEHYDE CYS-ASP-PRO-GLY-TYR-ILE-GLY-SER-ARG 5-Chlorosalicylaldehyde 2-CHLORO-3-HYDROXYBENZALDEHYDE 97

  • 2-chloro-6-hydroxy-benzaldehyd
  • 6-CHLOROSALICYLALDEHYDE
  • 2-CHLORO-6-HYDROXYBENZALDEHYDE
  • 6-chloro salicyaldehyde
  • 6-chloro salicyaldehyde 2-chloro-6-hydroxybenzaldehyde
  • Benzaldehyde, 2-chloro-6-hydroxy-
  • 6-Chlorosalicylaldehyde, 3-Chloro-2-formylphenol
  • 6-Chloro-2-hydroxybenzaldehyde
  • 4-Bromo-5-fluoroacetophenone
  • 18362-30-6