ChemicalBook > CAS DataBase List > Retinyl propionate

Retinyl propionate

Suggestions for use

Product Name: Retinyl propionate
CAS No.: 7069-42-3
Chemical Name: Retinyl propionate
Synonyms: VITAMIN A PROPIONATE;Retinol propionate;Einecs 230-363-2;Retinylpropionat;RETINYL PROPIOTE;RETINYL PROPIONATE;Retinol,propanoate;15-Retinol Propanoate;Vitamin A Impurity 37;Retinol, 15-propanoate
CBNumber: CB3188398
Molecular Formula: C23H34O2
Formula Weight: 342.51
MOL File: 7069-42-3.mol

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Retinyl propionate Property

Boiling point:: 453.7±14.0 °C(Predicted)
Density: 0.963±0.06 g/cm3(Predicted)
vapor pressure: 0-0Pa at 20-96.2℃
Flash point:: 128 °C
storage temp.: 2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form: Oil
color: Pale Yellow to Yellow
biological source: synthetic
Specific Activity: ~2500U/mg
BRN: 2475675
Stability:: Light Sensitive
LogP: 9.12 at 25℃

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Safety

Hazard Codes: Xn,T
Risk Statements: 38-63-53-61
Safety Statements: 53-45
WGK Germany: 1
F: 1-8-10

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H360May damage fertility or the unborn child

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 87809
Product name: Retinyl propionate
Purity: ≥98.0% (sum of isomers, HPLC), ~2500U/mg
Packaging: 25g
Price: $110
Updated: 2025/07/31

Sigma-Aldrich

Product number: 87809
Product name: Retinyl propionate
Purity: ≥98.0% (sum of isomers, HPLC), ~2500U/mg
Packaging: 100g
Price: $310
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR1668
Product name: Retinyl Propionate
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 1g
Price: $138
Updated: 2025/07/31

TRC

Product number: R275550
Product name: RetinylPropionate(StabilizedwithBHT)90%
Packaging: 100g
Price: $950
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 72272
Product name: RetinylPropionate(StabilizedwithBHT)90%
Packaging: 5G
Price: $2200
Updated: 2021/12/16

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Retinyl propionate Chemical Properties,Usage,Production

Suggestions for use

Usage levels of retinyl propionate in skin care range from 0.1–0.4%. It is often paired with niacinamide because this B vitamin enhances the stability and bioavailability of retinyl propionate.

Description

Retinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.

Chemical Properties

Thick Yellow Oil

Uses

Retinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.

Biochem/physiol Actions

Retinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.

Side effects

Side effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.

Structure and conformation

Retinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.

References

[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.

Retinyl propionate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Retinyl propionate manufacturers

Jinan Ruitong Biotech Co., Ltd.

Product: Retinyl propionate 7069-42-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1
Release date: 2025-09-08

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Retinyl propionate 7069-42-3
Price: US $99.00-45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-11-14

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Retinyl propionate;Vitamin A Propionate 7069-42-3
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥99%
Supply Ability: 20tons
Release date: 2025-03-03

7069-42-3, Retinyl propionateRelated Search:

Riboflavin Retinyl acetate Vitamin A palmitate Clobetasol propionate Betamethasone 17,21-dipropionate N-PENTYL PROPIONATE β-Carotene Vitamin B12 D-Biotin Vitamin A TRANS,TRANS-2,4-HEXADIENYL ACETATE RETINYL PALMITATE, [RETINOL 15-3H] axerophthene Retinyl propionate 2,4-HEXADIENYL PROPIONATE RETINYL PALMITATE, [PALMITATE-1-14C] Vitamin K2 L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT

RETINYL PROPIONATE

VITAMIN A PROPIONATE

Retinol,propanoate

ALL TRANS-RETINOL PROPIONATE

VITAMIN-A-PROPIONATE, ~2500 U/MG*

VITAMIN-A-PROPIONATE 2500 U MG 98+%

Retinylpropionat

Propanoic acid (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2,4,6,8-nonatetrenyl ester

Retinol propionate

Einecs 230-363-2

Propionic acid, retinol ester

15-Retinol Propanoate

Retinyl Propionate (Stabilized with BHT) 90%

RETINYL PROPIOTE

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl propionate

Retinol, 15-propanoate

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl]propanoate

RETINYL PROPIONATE USP/EP/BP

7069-42-3 C23H34O2 RETINYL PROPIONATE

Retinyl Propionate/Vitamin A Propionate

Vitamin A Impurity 37

Retinyl Propionate (Stabilized with BHT) 90%

7069-42-3

supplement

Intermediates & Fine Chemicals

Pharmaceuticals

Retinoids