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ChemicalBook > CAS DataBase List > Retinyl propionate

Retinyl propionate

Suggestions for use
Product Name
Retinyl propionate
CAS No.
7069-42-3
Chemical Name
Retinyl propionate
Synonyms
VITAMIN A PROPIONATE;Retinol propionate;Einecs 230-363-2;Retinylpropionat;RETINYL PROPIOTE;RETINYL PROPIONATE;Retinol,propanoate;15-Retinol Propanoate;Retinol, 15-propanoate;ALL TRANS-RETINOL PROPIONATE
CBNumber
CB3188398
Molecular Formula
C23H34O2
Formula Weight
342.51
MOL File
7069-42-3.mol
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Retinyl propionate Property

Boiling point:
453.7±14.0 °C(Predicted)
Density 
0.963±0.06 g/cm3(Predicted)
vapor pressure 
0-0Pa at 20-96.2℃
Flash point:
128 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Oil
color 
Pale Yellow to Yellow
BRN 
2475675
Stability:
Light Sensitive
LogP
9.12 at 25℃
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Safety

Hazard Codes 
Xn,T
Risk Statements 
38-63-53-61
Safety Statements 
53-45
WGK Germany 
1
1-8-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
87809
Product name
Retinyl propionate
Purity
≥98.0% (sum of isomers, HPLC), ~2500U/mg
Packaging
25g
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
87809
Product name
Retinyl propionate
Purity
≥98.0% (sum of isomers, HPLC), ~2500U/mg
Packaging
100g
Price
$291
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1668
Product name
Retinyl Propionate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$128
Updated
2024/03/01
TRC
Product number
R275550
Product name
RetinylPropionate(StabilizedwithBHT)90%
Packaging
100g
Price
$950
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
72272
Product name
RetinylPropionate(StabilizedwithBHT)90%
Packaging
5G
Price
$2200
Updated
2021/12/16
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Retinyl propionate Chemical Properties,Usage,Production

Suggestions for use

Usage levels of retinyl propionate in skin care range from 0.1–0.4%. It is often paired with niacinamide because this B vitamin enhances the stability and bioavailability of retinyl propionate.

Description

Retinyl propionate (RP) is a less well-known, but pretty interesting member of the retinoids, aka the "royal family of skincare".Similar to retinyl palmitate, retinyl Propionate is also a retinol ester with retinol and propionic acid being attached together.

Chemical Properties

Thick Yellow Oil

Uses

Retinyl Propionate is a Vitamin A ester derivative. Retinyl Propionate is a hypermitotic agent that is used in cosmetic formulations.This compound contains an unknown cis isomer.

Biochem/physiol Actions

Retinyl propionate, a derivative of retinol, is a fatty acid that is used as a sample preparation for copper-complexed collagen[1]. In metabolic processes, retinyl propionate is metabolized primarily into retinol (ROL) in the viable epidermis and dermis whereas ROL is esterified into retinyl palmitate (RPalm) and metabolized into the inactive retinoid 14‐hydroxy‐4,14‐retro‐retinol (14‐HRR)[2]. Retinol and its derivatives effectively intervene in the skin aging process. The matrix effect of retinyl propionate can be seen in the skin cells, bone cells, and cartilage tissue. Retinyl propionate has been shown to increase calcium pantothenate transport rates in human serum and also has a film-forming polymer effect.

Side effects

Side effects of using retinol may include: redness, irritation, burning, itching, dry skin, flaking and peeling of the skin, increased sensitivity to the sun, and skin cancer.

Structure and conformation

Retinyl propionate is closest in molecular size to pure retinoic acid with just three additional carbons. Vitamin A palmitate has an additional 16 carbons, making it too large to reach the dermis effectively.

References

[1] Wang Q, et al. The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging. Journal of Cosmetic Dermatology, 2023; 22: 2040-2049.
[2] Yang Y, et al. Hydrophobically modified inulin based nanoemulsions for enhanced stability and transdermal delivery of retinyl propionate. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2022; 653: 129883.

Retinyl propionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Retinyl propionate Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Retinyl propionate manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Retinyl propionate 7069-42-3
Price
US $99.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-14
Hebei Kingfiner Technology Development Co.Ltd
Product
RETINYL PROPIONATE 7069-42-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500000kg
Release date
2024-05-22
Henan Fengda Chemical Co., Ltd
Product
Retinyl propionate 7069-42-3
Price
US $32.00-1.40/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-07

7069-42-3, Retinyl propionateRelated Search:


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  • VITAMIN A PROPIONATE
  • Retinol,propanoate
  • ALL TRANS-RETINOL PROPIONATE
  • VITAMIN-A-PROPIONATE, ~2500 U/MG*
  • VITAMIN-A-PROPIONATE 2500 U MG 98+%
  • Retinylpropionat
  • Propanoic acid (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexene-1-yl)-2,4,6,8-nonatetrenyl ester
  • Retinol propionate
  • Einecs 230-363-2
  • Propionic acid, retinol ester
  • 15-Retinol Propanoate
  • Retinyl Propionate (Stabilized with BHT) 90%
  • RETINYL PROPIOTE
  • (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl propionate
  • Retinol, 15-propanoate
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenyl]propanoate
  • RETINYL PROPIONATE USP/EP/BP
  • 7069-42-3 C23H34O2 RETINYL PROPIONATE
  • Retinyl Propionate/Vitamin A Propionate
  • 7069-42-3
  • supplement
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Retinoids